Rchr
J-GLOBAL ID：200901004534197270   Update date: Oct. 05, 2024

Yoshida Yukiko

ヨシダ ユキコ | Yoshida Yukiko
Affiliation and department：
Tokyo Metropolitan Institute of Medical Science Laboratory of Protein Metabolism

About Tokyo Metropolitan Institute of Medical Science Laboratory of Protein Metabolism


Job title： Laboratory Head
Homepage URL  (1)： https://www.igakuken.or.jp/pro-meta/
Research field  (2)： Applied biochemistry ,  Molecular biology
Research keywords  (7)： Ubiquitin ,  タンパク質品質管理 ,  タンパク質分解 ,  糖鎖 ,  quality control ,  ubiquitin-proteasome ,  Sugar chain
Research theme for competitive and other funds  (21)：
  • 2024 - 2026 胚発生における小胞体関連分解基質の網羅的同定と寿命解析
  • 2020 - 2026 細胞質における糖鎖生物学-細胞恒常性維持の包括的理解を目指して
  • 2022 - 2025 Positive and negative regulation of the proteasome by the glycoprotein-type transcription factor Nrf1
  • 2018 - 2024 神経変性の原因となるタンパク質微粒子の形成と伝播機構
  • 2019 - 2022 細胞質の糖鎖除去不全が生体に異常を引き起こす分子機構の解明
Show all
Papers (53)：
  • Akinori Endo, Masayuki Komada, Yukiko Yoshida. Ubiquitin-mediated endosomal stress: A novel organelle stress of early endosomes that initiates cellular signaling pathways. BioEssays. 2024
  • Tadashi Satoh, Maho Yagi-Utsumi, Nozomi Ishii, Tsunehiro Mizushima, Hirokazu Yagi, Ryuichi Kato, Yuriko Tachida, Hiroaki Tateno, Ichiro Matsuo, Koichi Kato, et al. Structural basis of sugar recognition by SCFFBS2 ubiquitin ligase involved in NGLY1 deficiency. FEBS letters. 2024
  • Yukiko Yoshida, Tsuyoshi Takahashi, Nozomi Ishii, Ichiro Matsuo, Satoshi Takahashi, Haruka Inoue, Akinori Endo, Hikaru Tsuchiya, Meari Okada, Chikara Ando, et al. Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation. Molecular Cell. 2024. 84. 16. 3115-3127.e11
  • Haruhiko Fujihira, Keiko Sato, Yuji Nishiuchi, Takefumi Murase, Yuka Matsuda, Yukiko Yoshida, Takayuki Kamei, Tadashi Suzuki. ELISA-based highly sensitive assay system for the detection of endogenous NGLY1 activity. Biochemical and Biophysical Research Communications. 2024. 710. 149826-149826
  • Akinori Endo, Toshiaki Fukushima, Chikage Takahashi, Hikaru Tsuchiya, Fumiaki Ohtake, Sayaka Ono, Tony Ly, Yukiko Yoshida, Keiji Tanaka, Yasushi Saeki, et al. USP8 prevents aberrant NF-κB and Nrf2 activation by counteracting ubiquitin signals from endosomes. Journal of Cell Biology. 2024. 223. 3
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MISC (18)：
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Education (1)：
  • - 1996 The University of Tokyo
Professional career (2)：
  • 農学
  • 農学 (東京大学)
Work history (4)：
  • 2023/04 - 現在 Tokyo Metropolitan Institute of Medical Science Laboratory of Protein Metabolism Laboratory Head
  • 2009/04 - 2023/03 Tokyo Metropolitan Institute of Medical Science Ubiquitin project Researcher
  • 1998/01 - 2009/03 Tpkyo Metropolitan Institute of Medical Science
  • 1994/04 - 1997/12 RIKEN Molecular Glycobiology, Frontier Research Program Researcher
Awards (3)：
  • 2022 - JB reviewer award
  • 2004 - 農芸化学会奨励賞
  • 2003 - 東京都職員表彰
Association Membership(s) (1)：
農芸化学会 生化学会 分子生物学会 糖質学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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