Research theme for competitive and other funds (8):
2024 - 2027 細胞外小胞を応用した肥満糖尿病の新規治療戦略の開発
2021 - 2026 母児概日リズム同期と次世代疾患感受性の多層多元的代謝リズムパネルからの理解
2021 - 2024 腸管内分泌細胞の発生・発達に対する短鎖脂肪酸の意義の検討
2018 - 2021 Novel therapy for obesity and diabetes through intestinal bile acid metabolism
2015 - 2018 Novel therapy for metabolic diseases through intestinal environment by intestinal hormone
2012 - 2015 The therapy for metabolic disorder by immune-regulation of gut microbiome.
2009 - 2011 the hepatic immune therapy for metabolic disease
2007 - 2008 The role of immune system to non-alcoholic fatty liver disease
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Papers (125):
Takayuki Toshimitsu, Junichiro Irie. An update and overview of the various health-related benefits of probiotics: A focus on clinical trials demonstrating efficacy, tolerability and use in patients with impaired glucose tolerance and type 2 diabetes. Diabetes, Obesity and Metabolism. 2025
Na Yao, Kenichiro Kinouchi, Manami Katoh, Kousha Changizi Ashtiani, Sherif Abdelkarim, Hiroyuki Morimoto, Takuto Torimitsu, Takahide Kozuma, Akihide Iwahara, Shotaro Kosugi, et al. Maternal circadian rhythms during pregnancy dictate metabolic plasticity in offspring. Cell metabolism. 2025. 37. 2. 395-412
Hidenori Shimizu, Junki Miyamoto, Keiko Hisa, Ryuji Ohue-Kitano, Hiromi Takada, Mayu Yamano, Akari Nishida, Daiki Sasahara, Yuki Masujima, Keita Watanabe, et al. Sucrose-preferring gut microbes prevent host obesity by producing exopolysaccharides. Nature communications. 2025. 16. 1. 1145-1145
Shiro Otake, Shotaro Chubachi, Junki Miyamoto, Yuri Haneishi, Tetsuya Arai, Hideto Izuka, Takashi Shimada, Kaori Sakurai, Shinichi Okuzumi, Hiroki Kabata, et al. Impact of smoking on gut microbiota and short-chain fatty acids in human and mice: Implications for COPD. Mucosal Immunology. 2024
2024/04 - 現在 Kansai Medical University School of Medicine Department of Internal Medicine Clinical Professor
2021/06 - 2024/03 Keio University School of Medicine Associate Professor
2013/10 - 2021/05 Keio University School of Medicine
Association Membership(s) (7):
日本臨床栄養学会
, JAPAN SOCIETY FOR THE STUDY OF OBESITY
, THE JAPAN ENDOCRINE SOCIETY
, THE JAPAN DIABETES SOCIETY
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
, 日本抗加齢医学会
, 日本肥満症治療学会