Rchr
J-GLOBAL ID:200901009179469800
Update date: Apr. 15, 2025 Yoshiji Hitoshi
ヨシジ ヒトシ | Yoshiji Hitoshi
Affiliation and department: Job title:
Lecturer
Other affiliations (1): Homepage URL (1): http://www.naramed-u.ac.jp/~3int/ Research field (1):
Gastroenterology
Research keywords (10):
portal hypertension
, liver cirrhosis
, 血管新生
, NAFLD
, 肝線維化
, 肝癌
, NASH
, hepatocellular carcinoma
, liver fibrosis
, Angiogenesis
Research theme for competitive and other funds (21): - 2024 - 2026 Pathophysiological analysis and therapeutic development based on vWF-ADAMTS13 regulation for poor prognostic factors in liver cirrhosis
- 2022 - 2025 血液凝固制御因子ADAMTS13による急性肝不全新規治療法とバイオマーカーの開発
- 2021 - 2024 Novel Liver Cirrhosis Treatment by Drug Repositioning and Leaky Gut Control
- 2021 - 2024 歯周病と慢性肝疾患病態の関連解明-新たな肝疾患進展予防施策の探索
- 2021 - 2023 Development research of novel pathophysiology and therapy for hepatorenal syndrome in cirrhosis-Thrombotic microangiopathy and recombinant ADAMTS13 therapy-
- 2017 - 2020 Development of therapeutic method to suppress liver disease progression by drug repositioning
- 2017 - 2020 Therapeutic effect of Equol on gut microbiome - mediated NASH progression
- 2016 - 2020 Drug repositioning を用いた多面的アプローチによる肝疾患進展抑制治療法の開発
- 2015 - 2018 Identification of novel treatment and biomarkers based on pharmacokinetics in patients with hepatocellular carcinoma
- 2014 - 2017 Development of new therapeutic approaches against chronic liver diseases with combination of hepatic progenitor cells and clinical available agents
- 2014 - 2017 Establishment of new treatment targeting lifestyle diseases and coagulation fibrinolytic system related to the development of NASH
- 2014 - 2016 肝前駆細胞と既存薬剤を用いた肝疾患進展予防法の開発
- 2011 - 2013 慢性肝疾患進展制御法の確立:効果予測に基づく個別化医療
- 2011 - 2013 Gut-liver axis mediated by endotoxin and innate immunity
- 2008 - 2010 Crosstalk of renin-angiotensin system in the chronic liver diseases and therapeutic applications
- 2007 - 2009 マクロファージと肝障害:Toll-like受容体制御による新規治療の探索
- 2005 - 2007 Establishment of order-made therapy for liver fibrosis and hepatocellular carcinoma via angiogenesis suppression
- 2005 - 2006 Role of radixin in cholestasis
- 2002 - 2004 Immunogene therapy for hepatocellular carcinoma : combination with local gene therapy
- 2002 - 2003 Mechanistic Investigation and future clinical application of anti-angiogenic theraphy in hepatacellular carcinoma
- 1998 - 2000 In vivo gene therapy for hepatocellular carcinoma and colorectal carcinoma using suicide genes and cytokine genes
Show all
Papers (572): -
Atsushi Tanaka, Masanori Abe, Tadashi Namisaki, Shinji Shimoda, Mikio Zeniya, Akio Ido, Hitoshi Yoshiji, Hiromasa Ohira, Kenichi Harada, Yuko Kakuda, et al. A placebo-controlled Phase 2 trial of E6011, anti-human fractalkine monoclonal antibody, in primary biliary cholangitis. JOURNAL OF TRANSLATIONAL AUTOIMMUNITY. 2025. 10
-
Yukihisa Fujinaga, Tadashi Namisaki, Yuki Tsuji, Akihiko Shibamoto, Takahiro Kubo, Aritoshi Koizumi, Takuya Matsuda, Takashi Inoue, Satoshi Iwai, Fumimasa Tomooka, et al. Fibrosis stage is an independent predictor of liver-related complications in primary biliary cholangitis. Hepatology Research. 2025
-
Hiroaki Takaya, Tadashi Namisaki, Yusuke Komeda, Hiroki Kinoshita, Naoki Nishimura, Yuki Tsuji, Shinya Sato, Norihisa Nishimura, Ko Saito, Shigeyuki Aizawa, et al. Low Intrahepatic Distant Recurrence Rate Following RFA Using Linear Mode in Patients With Hepatocellular Carcinoma. JGH OPEN. 2025. 9. 4
-
Hiroaki Takaya, Tadashi Namisaki, Yusuke Komeda, Hiroki Kinoshita, Naoki Nishimura, Yuki Tsuji, Shinya Sato, Norihisa Nishimura, Ko Saito, Shigeyuki Aizawa, et al. Low Intrahepatic Distant Recurrence Rate Following RFA Using Linear Mode in Patients With Hepatocellular Carcinoma. JGH open : an open access journal of gastroenterology and hepatology. 2025. 9. 4. e70145
-
Fumimasa Tomooka, Koh Kitagawa, Akira Mitoro, Yukihisa Fujinaga, Norihisa Nishimura, Tadashi Namisaki, Takemi Akahane, Kosuke Kaji, Shohei Asada, Shinya Sato, et al. Unilateral drainage and chemotherapy prolong the patency of a plastic stent placed above the sphincter of Oddi in patients with malignant hilar biliary obstruction. DEN open. 2025. 5. 1. e404
more... MISC (976): -
Norihisa Nishimura, Kosuke Kaji, Shinya Sato, Tadashi Namisaki, Hitoshi Yoshiji. TOFOGLIFLOZIN AMELIORATES PORTAL HYPERTENSION ALONG WITH LIVER FIBROSIS PROGRESSION BY INHIBITION OF SINUSOIDAL CAPILLARIZATION IN RATS WITH LIVER CIRRHOSIS. HEPATOLOGY. 2024. 80. S1625-S1625
-
Nagisa Hara, Atsushi Hiraoka, Masato Nakai, Makoto Shiraki, Tadashi Namisaki, Hisamitsu Miyaaki, Takuro Hisanaga, Hirokazu Takahashi, Hideko Ohama, Fujimasa Tada, et al. CLINICAL IMPACT OF HARM REDUCTION IN PATIENTS WITH CHRONIC LIVER DISEASE AND ALCOHOL USE DISORDER BY BRIEF INTERVENTION IN A HEPATOLOGY OUTPATIENT UNIT. HEPATOLOGY. 2024. 80. S1106-S1106
-
Kosuke Kaji, Norihisa Nishimura, Shinya Sato, Tadashi Namisaki, Hitoshi Yoshiji. GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST, SEMAGLUTIDE PREVENTS LIVER CIRRHOSIS-INDUCED SKELETAL MUSCLE ATROPHY IN DIABETIC MICE. HEPATOLOGY. 2024. 80. S1603-S1604
-
Shinya Sato, Hiroaki Takaya, Norihisa Nishimura, Kosuke Kaji, Tadashi Namisaki, Takemi Akahane, Hitoshi Yoshiji. DIABETES IS A RISK FACTOR FOR SARCOPENIA OF PATIENTS WITH METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS-DRIVEN CIRRHOSIS. HEPATOLOGY. 2024. 80. S451-S452
-
Tadashi Namisaki, Shinya Sato, Kosuke Kaji, Norihisa Nishimura, Hitoshi Yoshiji. PROGNOSTIC SIGNIFICANCE OF SKELETAL MUSCLE MASS IN PATIENTS WITH ALCOHOLIC CIRRHOSIS. HEPATOLOGY. 2024. 80. S1110-S1110
more... Patents (8): Books (1): - 肝がん・肝硬変に対する栄養療法の新時代
アークメディア 2012 ISBN:9784875831600
Education (2): - - 1993 Nara Medical University
- - 1993 Nara Medical University Graduate School, Division of Medicine
Professional career (1): - (BLANK) (Nara Medical University)
Work history (14): - 2015/07 - 現在 奈良県立医大 消化器代謝内科 主任教授
- 2015 - 現在 Nara Medical University Department of Gastroenterology Chairman and Full Professor
- 2012 - 現在 奈良県立医大 准教授
- 2012 - 2015 Nara Medical University Department of Gastroenterology Associate Professor
- 2007 - 2012 Nara Medical University Department of Gastroenterology Lecturer
- 2007 - - 奈良県立医大 講師
- 2001 - - 奈良県立医大 助手
- 2001 - - Nara Medical University, Assistant Professor
- 1997 - 2000 奈良県立医大 研究生
- 1997 - 2000 Nara Medical University, Research Fellow.
- 1994 - 1997 米国立癌研究所 (NCI/NIH)客員研究員
- 1994 - 1997 National Cancer Institute, USA, Visiting Fellow
- 1993 - 1994 奈良県立医大 研究生
- 1993 - 1994 Nara Medical University, Research Fellow.
Show all
Committee career (10): - - 現在 肝臓学会・糖尿病学会合同「肝と糖尿病・代謝研究会」委員
- 門脈圧亢進症学会理事
- 消化器内視鏡学会社団評議員
- 次世代再生医療肝再生審査部WG座長
- 日本医療安全審査機構 事例審査部会長
- 日本内科学会理事
- 癌転移学会理事
- Founding member of ILCA (International Liver Cancer Association)
- 日本消化器病学会財団評議員
- 肝臓学会評議員・理事
Show all
Awards (7): Association Membership(s) (10):
NYAS (New York Academy of Science)
, AACR (American Association of Cancer Research)
, 日本消化器内視鏡学会
, 日本肝臓学会
, アメリカ癌学会
, 日本癌学会
, 日本消化器病学会
, 日本内科学会
, 欧州肝臓学会
, American Association of the study of liver diseases
Return to Previous Page