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J-GLOBAL ID：200901010646699227   Update date: Nov. 16, 2024

Suzuki Hiroaki

スズキ ヒロアキ | Suzuki Hiroaki
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Affiliation and department：
Tokyo Medical University

About Tokyo Medical University


Research field  (2)： Pharmacology ,  Neuroscience - general
Research keywords  (2)： 神経科学 ,  Neuroscience
Research theme for competitive and other funds  (8)：
  • 2024 - 2027 Paraspeckle形成異常に着目した新規ALS治療戦略の確立
  • 2021 - 2024 TDP-43発現亢進を標的とした筋萎縮性側索硬化症の新たな治療戦略の構築
  • 2018 - 2021 リボソーム機能異常に着目したALS/FTLDの新規発症メカニズムの解明
  • 2013 - 2016 Elucidation of molecular pathomechanism of TDP-43 and FUS-linked ALS
  • 2010 - 2013 小胞体ストレスを介した運動神経細胞変性機構の解析
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Papers (24)：
  • Hiroaki Suzuki, Masaaki Matsuoka. Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA. Journal of neurochemistry. 2021. 158. 3. 753-765
  • Ichie Hara, Hiroaki Suzuki, Shinya Kusakari, Masaaki Matsuoka. [Practical training of pharmacokinetics with an web-based simulation application]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 2020. 155. 1. 51-55
  • Hiroaki Suzuki, Yoshio Shibagaki, Seisuke Hattori, Masaaki Matsuoka. C9-ALS/FTD-linked proline-arginine dipeptide repeat protein associates with paraspeckle components and increases paraspeckle formation. Cell death & disease. 2019. 10. 10. 746-746
  • Hiroaki Suzuki, Yoshio Shibagaki, Seisuke Hattori, Masaaki Matsuoka. The proline-arginine repeat protein linked to C9-ALS/FTD causes neuronal toxicity by inhibiting the DEAD-box RNA helicase-mediated ribosome biogenesis. Cell death & disease. 2018. 9. 10. 975-975
  • Hiroaki Suzuki, Masaaki Matsuoka. hnRNPA1 autoregulates its own mRNA expression to remain non-cytotoxic. Molecular and cellular biochemistry. 2017. 427. 1-2. 123-131
ｍore...
MISC (1)：
  • Hiroaki Suzuki. Physiological and pathological roles of TMEM106B: a novel component of amyloid fibrils identified by cryo-EM analysis. Journal of Clinical and Experimental Medicine (IGAKU NO AYUMI). 2022. 283. 13. 1138-1143
Professional career (1)：
  • 博士(医学) (慶應義塾大学)
Committee career (1)：
  • 2018/04 - 現在 日本薬理学会 学術評議員
Association Membership(s) (2)：
日本神経科学学会 ,  日本薬理学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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