Rchr
J-GLOBAL ID:200901010963920362   Update date: Sep. 13, 2024

Asai Daisuke

アサイ ダイスケ | Asai Daisuke
Affiliation and department:
Job title: Associate Professor
Other affiliations (3):
Homepage URL  (1): https://www.shoyaku.ac.jp/
Research field  (5): Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - analytical and physicochemistry ,  Molecular biochemistry ,  Biomaterials ,  Biomedical engineering
Research keywords  (8): Molecular cellular biology ,  Biological chemistry ,  Microbiology ,  Antimicrobial ,  Peptide science ,  Genetic engineering ,  Drug delivery system (DDS) ,  Biomaterial science
Research theme for competitive and other funds  (16):
  • 2024 - 2027 Development of a depot formulation that senses the bacterial infection environment and releases antimicrobial peptide drugs
  • 2020 - 2023 Resolving the unresolved antiviral mechanism of sulfated oligosaccharides
  • 2020 - 2023 Development of antimicrobial: Challenge by an artificial multi-functional bio-polymer
  • 2018 - 2021 Ultra-sensitive detection method of membrane antigens and its application to cancer companion diagnosis
  • 2017 - 2020 Development of molecular bases of next generation vaccine: Approach from antigen depot delivery system
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Papers (73):
  • Terada, K, Asai, D (Co-first author), Kang, JH, Mori, T, Katayama, Y. Activated tyrosine kinase c-Src-responsive artificial gene carrier: in vitro and in vivo evaluation. ChemistrySelect. 2024. 9. 1. e202303331
  • Kang, JH, Asai, D, Toita, R. Bisphenol A (BPA) and cardiovascular or cardiometabolic diseases. J. Xenobiot. 2023. 13. 4. 775-810
  • Shimotori, Y, Ogawa, N, Mamada, S, Miyakoshi, T, Masuda, H, Kitago, S, Shima, T, Asai, D, Kanamoto, T. Synthesis, odour characteristics, and antimicrobial activity of optically active (Z)-7-decen-4-olide and its derivatives. J. Oleo Sci. 2023. 72. 11. 1037-1048
  • Battulga, T, Dagaerbieke, A, Bai, C, Asai, D, Koshikawa, T, Takemura, H, Miyazaki, K, Yoshida, T. Electrostatic interaction between sulfated polysaccharides and oligopeptides from viral envelope glycoproteins using surface plasmon resonance. Carbohydr. Res. 2023. 528. 108815
  • Mingxue, B, Asai, D, Koshikawa, T, Takemura, H, Miyazaki, K, Yoshida, T. Synthesis and cytotoxic mechanism of sulfated alkyl oligosaccharides having potent anti-HIV activity. J. Fiber Sci. Technol. 2023. 79. 5. 101-111
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MISC (88):
  • 林桃花, 河村橘花, 千阪太聖, 藤生朱音, 梶川瑞穂, 金本大成, 淺井大輔. Design and preparation of infection-sensing peptide depot for Staphylococcus aureus. 日本薬学会年会要旨集(Web). 2024. 144th
  • 藤生朱音, 千阪太聖, 林桃花, 梶川瑞穂, 金本大成, 淺井大輔. Development of sustained release antimicrobial peptide drug responding to Psuedomonas aeruginosa-delived proteases. 日本薬学会年会要旨集(Web). 2024. 144th
  • Sakagami, H, Fukuchi, K, Asai, D, Kanamoto, T, Koshikawa, T, Takemura, H, Inomata, M, Aimi, H, Kikkawa, Y. Rapid virus inactivation by lignosulfonate. New Food Industry. 2022. 64. 2. 106-110
  • Sakagami, H, Fukuchi, K, Asai, D, Terakubo, S, Takemura, H, Horiuchi, M, Fujisawa, T, Suguro, M, Toeda, K, Yasui, T, et al. Rapid virus inactivation by alkaline extract of leaves of Sasa sp. New Food Industry. 2020. 62. 11. 785-790
  • Shi, H, Fukuchi, K, Asai, D, Terakubo, S, Takemura, H, Sakagami, H. Quantification of antitumor, antiviral and neuroprotective activity of twenty Kampo preparations. New Food Industry. 2020. 62. 8. 599-607
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Patents (6):
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Education (1):
  • - 2003 Kyushu University Graduate School of Sciences Department of Chemistry
Professional career (1):
  • Ph.D. (Kyushu University)
Work history (8):
  • 2020/09 - 現在 Showa Pharmaceutical University Laboratory of Microbiology, Faculty of Pharmaceutical Sciences Associate Professor
  • 2017/12 - 2020/08 St.Marianna University School of Medicine Department of Microbiology, Faculty of Medicine Junior Associate Professor
  • 2014/01 - 2018/03 National Institute of Infectious Diseases Department of Bacteriology II Project Researcher (concurrent)
  • 2006/04 - 2017/11 St. Marianna University School of Medicine Department of Microbiology, Faculty of Medicine Assistant Professor
  • 2009/08 - 2011/07 Duke University Department of Biomedical Engineering, Visiting Scholar; under Prof. Ashutosh Chilkoti (concurrent)
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Committee career (1):
  • The Japan Sosiety of Drug Delivery System; Councilor
Awards (4):
  • 2013 - 神奈川県感染症医学会 第72回神奈川県感染症医学会例会学術奨励賞 次世代医用材料の開発:薬物徐放のための生体吸収性注射ゲル
  • 2009 - 公益財団法人国際科学技術財団 2009年研究助成 疾患細胞選択的な遺伝子発現制御技術の創出と治療への応用
  • 2000 - 公益財団法人日本科学協会 笹川科学研究助成 核受容体コンホメーション法による環境ホルモン作用の評価
  • 1999 - 日本分析化学会 九州分析化学ポスター賞 内分泌撹乱物質(環境ホルモン)の女性ホルモン受容体結合性の解析
Association Membership(s) (7):
The Pharmaceutical Society of Japan ,  American Chemical Society ,  The Japanese Society for Biomaterials ,  The Japanese Association for Infectious Diseases ,  The Japanese Society for Virology ,  The Japanese Society of Drug Delivery System ,  The Japanese Biochemical Society
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