Gojo Satoshi

ゴジョウサトシ | Gojo Satoshi

Affiliation and department：
Job title： Professor

Research field (6)： Cardiovascular surgery , Genomics , Experimental pathology , Cell biology , Medical biochemistry , Molecular biology

Research theme for competitive and other funds (38)：

2024 - 2029 Promotion and Multifaceted Development of Clinical Application of Pulmonary Artery Augmentation Using Tissue Engineered Vascular Grafts for Pediatric Heart Diseases
2024 - 2027 Development of short-time decellularization procedure for tissue engineered vascular grafts allotransplantation
2022 - 2025 Development of a vascular prothesis regenerated in the patient's body using a decellularized xenogeneic cell-free device
2022 - 2025 Attempt to use skin tissue killed by high-pressure treatment technology as autologous regenerative vascular grafts
2022 - 2025 Development of Mitochondrial Disease Therapy by Mitochondrial DNA Replacement in Hematopoietic Stem Cells

2020 - 2025 A multifaceted study aiming at expanding the clinical application of autologous in vivo-tissue engineered vascular grafts

2021 - 2024 Construction of Multiple Sample Analysis System Using FRET System and Search for Inhibitors of Virus Polymerization Proteins

2021 - 2024 Development of an Optimal Chemical Processing for Allogeneic In Vivo Tissue Engineered Vascular Grafts

2019 - 2024 Pulmonary artery enlargement for congenital heart disease using connective tissue membrane using in vivo tissue engineering

2020 - 2023 Development of allogeneic in vivo-tissue engineered vascular graft preparation completed in the operating room without using special facilities

2019 - 2022 高圧処理化自家皮膚組織の”自己体内再生型”血管補填材料としての応用

2019 - 2021 Neutralizing antibody producing B cell deletion by CAR technology in Lysosomal diseases

2018 - 2021 RNA metabolism during cellular transition

2018 - 2021 Development of an optimal treatment method for using biomaterials as cardiovascular prostheses

2017 - 2021 Development of vascular grafts for auto implantation rapidly formed in patients using xenogeneic decellularized connective tissue tubules as scaffolds

2016 - 2021 Development of cardiovascular tissue using bio 3D printer, stem cell technology, and elucidation of cellular dynamics in tissue

2016 - 2020 Development of xenogeneic decellularized biotubes for off-the-shelf applications

2016 - 2019 Diversified deployment of "self-regenerating" connective tissue vascular grafts "Biotubes" for clinical applications.

2015 - 2019 New rehabilitation approach for cancer patients with skeletal metastases

2016 - 2018 Analysis of Non-coding RNA Y1 during iPS reprogramming

2015 - 2018 R&D of an axial flow blood pump for pediatric/partial assist use

2014 - 2017 An examination of mutation-specific precipitation factors for ventricular tachyarrhythmias in concealed inherited arrhythmia syndromes

2014 - 2017 Development of Isolated Mitochondria Transplantation

2015 - 2016 バイオ3Dプリンターを用いた尿管創生に向けた基礎的研究

2015 - 2016 Three-dimensional culture of reprogrammed brown adipocytes

2013 - 2016 Whole Heart Engineering with Decellularization and in vivo Incubation

2012 - 2016 Bone microenvironment affects cancer progression via mesenchymal stromal cells

2012 - 2015 Somatic cell to CMs by miRNA

2011 - 2013 Clinical Application of Echocardiographic Blood Flow Visualization System

2010 - 2012 慢性虚血性心疾患に対する在宅体外式カウンターパルセーション治療の有効性の検討

2010 - 2012 Regenerative medicine for heart failure in large animal models

2009 - 2011 Construction of the heart rehabilitation system by the assisted artificial heart which aimed at the cardiac functional recovery of serious heart failure

2005 - 2006 Development of Cell Transplantation System Using A Closed Culture for Heart Diseases

2002 - 2003 Differentiation induction of adult somatic stem cells into cardiomyocytes

2002 - 2003 移植臓器へのトリプトファン代謝酵素遺伝子導入による免疫学的寛容誘導

2000 - 2001 Gene Therapy for the Recovery from Left Ventricular Assist System

1999 - 2000 NEW INDEX FOR RIGHT VENTRICULAR FUNCTION USING 3D RECONSTRUCTION OF DISANCES BETWEEN SONOCRYSTALS IMPLANTED IN RIGHTVENTRICLE AND ITS APPLICATION ON RIGHT HEART FAILUREAFTER CARDIAC TRANSPLANTATION

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Papers (122)：

Takahiro Tsukimura, Daisuke Kami, Tomoko Shiga, Tadayasu Togawa, Satoshi Gojo, Hitoshi Sakuraba. Use of a mouse-human chimeric anti-α-galactosidase A monoclonal antibody as a reference for measuring serum antidrug antibody titers in patients with Fabry disease. Molecular Genetics and Metabolism. 2025. 144. 1. 109000-109000
Hiroki Kawano, Yuko Kawano, Chen Yu, Mark W LaMere, Matthew J McArthur, Michael W Becker, Scott W Ballinger, Satoshi Gojo, Roman A Eliseev, Laura M Calvi. Mitochondrial Transfer to Host Cells from Ex Vivo Expanded Donor Hematopoietic Stem Cells. Cells. 2023. 12. 11
Yosuke Suzuki, Daisuke Kami, Toshihiko Taya, Arata Sano, Takehiro Ogata, Satoaki Matoba, Satoshi Gojo. ZLN005 improves the survival of polymicrobial sepsis by increasing the bacterial killing via inducing lysosomal acidification and biogenesis in phagocytes. Frontiers in immunology. 2023. 14. 1089905-1089905
Daisuke Kami, Toshimasa Ishizaki, Toshihiko Taya, Akira Katoh, Hiroyuki Kouji, Satoshi Gojo. A novel mRNA decay inhibitor abolishes pathophysiological cellular transition. Cell death discovery. 2022. 8. 1. 278-278
Akira Shikuma, Daisuke Kami, Ryotaro Maeda, Yosuke Suzuki, Arata Sano, Toshihiko Taya, Takehiro Ogata, Anne Konkel, Satoaki Matoba, Wolf-Hagen Schunck, et al. Amelioration of Endotoxemia by a Synthetic Analog of Omega-3 Epoxyeicosanoids. Frontiers in Immunology. 2022. 13

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MISC (18)：

Gondai T, Yamanami M, Kanda K, Inoue T, Kawajiri H, Watanabe T, Kami D, Gojo S, Yaku H. IMPROVEMENT OF THE SIMPLER AND SHORTER DECELLULARIZATION PROCEDURE OF IN VIVO TISSUE ENGINEERED VASCULAR GRAFT USED FOR ALLOGENEIC TRANSPLANTATION. International J Artif. Org. 2022. 45. 9. 786-787
神田圭一, 山南将志, 井上知也, 渡辺太治, 坂井修, 上大介, 五條理志, 夜久均. 患者体内で作成する自家結合組織代用血管臨床開始後の応用拡大に向けた取り組みについて. 人工臓器. 2019. 48. 2. S-204
神田圭一, 山南将志, 井上知也, 渡辺太治, 坂井修, 上大介, 五條理志, 夜久均. 希少疾病に対する人工臓器研究・開発の実用化、事業化に向けての取り組み生体内組織工学による代用血管開発への取り組みとよろず相談所での面談. 人工臓器. 2019. 48. 2. S-71
山南将志, 神田圭一, 森本和樹, 井上知也, 渡辺太治, 坂井修, 上大介, 五條理志, 夜久均. 脱細胞化同種結合組織膜の血管移植片への応用. 人工臓器. 2019. 48. 1. 41-41
井上知也, 神田圭一, 山南将志, 渡辺太治, 坂井修, 上大介, 五條理志, 夜久均. エタノール・グルタールアルデヒド処理による生体内組織工学代用血管の物理特性変化. 日本心臓血管外科学会学術総会抄録集. 2019. 49回. [PP-240]

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