Rchr
J-GLOBAL ID:200901012337989310
Update date: Feb. 25, 2025 Matsumoto Mitsuyo
マツモト ミツヨ | Matsumoto Mitsuyo
Affiliation and department: Research field (2):
Molecular biology
, Tumor biology
Research keywords (4):
微小環境
, 転写因子
, がん
, Environmental and Biological Chemistry
Research theme for competitive and other funds (8): - 2022 - 2026 転写因子BACH1と鉄による膵臓癌上皮間葉転換と幹細胞性の促進機構の解明
- 2020 - 2025 Development of anti-cancer strategy by exploiting BACH1 addiction
- 2019 - 2022 上皮間葉移行とフェロトーシス感受性により規定されるRAS変異癌の悪性化と脆弱性
- 2017 - 2019 Identification of the mechanism by which SAM synthesis inhibition induces erythroblast maturation
- 2016 - 2019 The effect of BACH1 on malignant transformation of tumor
- 2013 - 2016 Methods rewriting epigenome as the target of methyonine adenosyltransferase II
- 2010 - 2012 The investigation of function of repressor Bach1 in microenvironment of the tumor and the application to a mouse model for cancer stem cell transplantation.
- 2007 - 2009 Estrogen signaling ability in human endometrial cancer and breastcancer through the cancer-stromal interaction.
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Papers (51): -
Miki Watanabe-Matsui, Shun Kadoya, Kei Segawa, Hiroki Shima, Tadashi Nakagawa, Yuko Nagasawa, Shuichiro Hayashi, Mitsuyo Matsumoto, Mariko Ikeda, Akihiko Muto, et al. Heme regulates protein interactions and phosphorylation of BACH2 intrinsically disordered region in humoral response. iScience. 2025. 28. 1. 111529-111529
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Kazuma Nakajima, Hironari Nishizawa, Guan Chen, Shunichi Tsuge, Mie Yamanaka, Machi Kiyohara, Riko Irikura, Mitsuyo Matsumoto, Kozo Tanaka, Rei Narikawa, et al. Intracellular biliverdin dynamics during ferroptosis. Journal of biochemistry. 2024
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Takeshi Kurasawa, Akihiko Muto, Mitsuyo Matsumoto, Kyoko Ochiai, Kazutaka Murayama, Kazuhiko Igarashi. Absolute quantification of BACH1 and BACH2 transcription factors in B and plasma cells reveals their dynamic changes and unique roles. The Journal of Biochemistry. 2024. 176. 6. 449-459
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Hironari Nishizawa, Mitsuyo Matsumoto, Mie Yamanaka, Riko Irikura, Kazuma Nakajima, Keisuke Tada, Yoshiaki Nakayama, Morichika Konishi, Nobuyuki Itoh, Ryo Funayama, et al. BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion. Cell reports. 2024. 43. 7. 114403-114403
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Liang Liu, Mitsuyo Matsumoto, Miki Watanabe-Matsui, Tadashi Nakagawa, Yuko Nagasawa, Jingyao Pang, Bert K K Callens, Akihiko Muto, Kyoko Ochiai, Hirotaka Takekawa, et al. TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22. International journal of molecular sciences. 2024. 25. 8
more... MISC (73): -
Intracellular iron metabolism by the transcription factor BACH1 and iron-deficient cell death in head and neck cancer. 日本癌学会学術総会抄録集(Web). 2024. 83rd
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BACH1 and TBK1 synergistically promote epithelial-mesenchymal transition via iron. 日本癌学会学術総会抄録集(Web). 2024. 83rd
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五十嵐和彦, 西澤弘成, 中村和樹, 松本光代. BACH1遺伝子ネットワークによる鉄流通と抗老化フェロトーシスシグナルの制御. 日本分子生物学会年会プログラム・要旨集(Web). 2024. 47th
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Construction and Evaluation of Cancer Cell Selective Drug Delivery System: III: Development pancreatic cancer of a selective drug delivery system to suppress the malignant progression. 日本化学会春季年会講演予稿集(Web). 2024. 104th
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堀内結翔, 石渡望, 藤田一寿, 西嶋政樹, 三瓶悠, 荒木保幸, 松本光代, 松本光代, 山吉麻子, 五十嵐和彦, et al. Construction of Chimeric Artificial Nucleic Acids (CANA) toward Pancreatic Cancer Treatments by Inhibition of Transcription Factor BACH1: III: Establishment of Molecular Design Strategy Based on In Vitro Analysis. 日本化学会春季年会講演予稿集(Web). 2024. 104th
more... Books (1): - Biosynthesis and Action of Estrogen in Gynecological Cancers
Research Signpost, India 2007
Professional career (1): Work history (5): - 2024/01 - 現在 東北大学多元物質科学研究所 助教
- 2014 - Tohoku University Graduate School of Medicine
- 2012 - Tohoku University Tohoku Medical Megabank Organization
- 2010 - 東北大学大学院医学系研究科 助教
- 2008 - がん集学的治療財団 若手研究員
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