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J-GLOBAL ID：200901013425403500 Update date: Mar. 31, 2025

Sako Yasuhito

サコヤスヒト | Sako Yasuhito

Affiliation and department：

Research field (3)： Environmental impact assessment , Infectious disease , Parasitology

Research keywords (5)： molecular biology , laboratory medicine , infectious diseases , parasitology , Parasitology

Research theme for competitive and other funds (40)：

2024 - 2027 Infection dynamics of the Schistosoma japonicum using a high-precision environmental analysis approach.
2024 - 2027 寄生虫症の迅速で高精度な網羅的種鑑別診断法の開発研究
2024 - 2027 メコン住血吸虫の撲滅に向けた多面的な融合対策プログラム作成と数理モデルによる感染リスク分析による「最後の一押し!」
2023 - 2026 国内に蔓延する寄生虫症、輸入寄生虫症の対策に資する研究開発
2022 - 2025 アジアの住血吸虫症撲滅を目指した革新的ポイント・オブ・ケア検査法ならびに環境汚染監視ツールの開発

2021 - 2024 Elucidating transmission dynamics for soil-transmitted helminths based on environmental DNA analysis

2020 - 2023 Development of an innovative differential diagnosis method for diphyllobothriasis and taeniasis

2015 - 2018 Studies on proteinases of Echinococcus multilocularis larva for their survival in the host and search for inhibitors

2015 - 2018 Epidemiological survey of human taeniasis/cysticercosis and animal cysticercosis and development of comprehensive detection method for soil-transmitted helminths.

2015 - 2018 Development of the detection method for animal cysticercosis and the investigation of the genetic factors for host specificity

2014 - 2016 有鉤条虫の比較ゲノム解析に基づく組織指向性の解明および遊離型DNA検査法の開発

2012 - 2015 Development of the quick diagnostic method for identifying Taenia asiatica and Taenia saginata for food safety and analysis of the gene causing the host specificity.

2012 - 2015 Molecular evolution and co-evolution in Taeniid cestode infections in the world

2012 - 2015 中国で蔓延している人獣共通寄生虫症(嚢虫症)の迅速・簡便な検査法の開発

2012 - 2014 LAMP法によるエキノコックス条虫の迅速検査法の開発および感染源対策への応用

2010 - 2012 多包虫症に関する分子、免疫、伝搬生態学的研究

2010 - 2011 難治性寄生虫病に関する遺伝子診断法の開発

2009 - 2011 Development of diagnostic methods for domestic animals infected with larval taeniid cestodes and application to risk management.

2009 - 2011 Speciation of Taeniid cestodes (Echinococcus spp. and Taenia spp.) in the world and co-evolution of the host-parasite relationship

2009 - 2010 アジア・アフリカで流行している人畜共通寄生虫病研究拠点形成(II)

2007 - 2010 北海道特有の地方病(特にエキノコックス症等)に関する総合研究及び臨床応用

2007 - 2009 アジア・アフリカで流行している人畜共通寄生虫病研究拠点形成

2007 - 2008 In situ localization of cysteine proteinase of Taenia solium cysticercus

2007 - 2008 エキノコックス症における寄生虫の発育分化と宿主免疫応答の動的解析

2006 - 2008 Molecular epidemiological survey and risk evaluation of livestock animals for control of taeniasis and cycticercosi s.

2005 - 2008 Speciation, pathogenicity and evolution of Echinococcus and Taenia tapeworms in Asia

2006 - 2007 エキノコックス症化学療法剤の標的分子候補としてのシステインプロテアーゼの解析

2003 - 2004 Severe Combined Immunodeficient(SCID) Mice As Animal Models for Human Echinococcosis

2000 - 2002 Immunodiagnosis for echinococcosis: international standardization, early diagnosis and evaluation of prognosis

2000 - 2001 分子生物学的アプローチによる難治性寄生虫感染症の血清診断法の開発

1999 - 2000 SERO-AND MOLECULAR-EPIDEMIOLOGICAL STUDY ON ECHINOCOCCOSIS AND CYSTICERCOSIS IN ASIA (2000)

1998 - 1999 MOLECULAR- AND IMMUNO-DIAGNOSIS FOR EMERGING/RE-EMERGING INFECTIOUS DISEASES, ECHINOCOCCOSIS AND CYSTICERCOSIS (1999)

1998 - 1999 SEVERE COMBINED IMMUNODEFICIENT (SCID) MICE AS ANIMAL MODELS FOR HUMAN CYSTICERCOSIS AND ECHINOCOCCOSIS (1999)

寄生虫感染症の血清診断法の開発

Development of Serodiagnosis of Parasite Infection

条虫DNA検出に基づく鑑別検査法の開発

有鉤嚢虫症血清検査法の開発

エキノコックス症血清検査法の開発

多包虫蛋白質分解酵素の解析

条虫-宿主の分子間クロストークの解明

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Papers (121)：

Dewi Masyithah Darlan, Hemma Yulfi, Sunna Vyatra Hutagalung, Merina Pangabean, Yunilda Andriyani, Irma Sepala Sari Siregar, Inke Nadia Diniyanti Lubis, Toni Wandra, Ivan Elisabeth Purba, Hiroshi Yamasaki, et al. A new focus of Taenia asiatica taeniasis in North Sumatra, Indonesia: Molecular confirmation and prevalence. Parasitology international. 2025. 105. 102996-102996
Mark June Revolteado, Marcello Otake Sato, Joseph Valencia, Mario Jiz, Eleonor Cervantes, Ralph Aniceto, Marianette Inobaya, Darren Gray, Catherine A Gordon, Pengfei Cai, et al. Seasonality and dynamics of schistosomiasis in the environment: usefulness of environmental DNA (eDNA) surveillance system at a community level for risk mapping schistosomiasis in Ekiran Village, Leyte, Philippines. mSphere. 2025. e0106124
Emmanuel John Tabilin, Darren J Gray, Mario A Jiz, Mary Lorraine Mationg, Marianette Inobaya, Eleonor Avenido-Cervantes, Megumi Sato, Marcello Otake Sato, Yasuhito Sako, Yi Mu, et al. Schistosomiasis in the Philippines: A Comprehensive Review of Epidemiology and Current Control. Tropical medicine and infectious disease. 2025. 10. 2
Emmanuel John Tabilin, Catherine A Gordon, Yi Mu, Mario Jiz, Marianette Inobaya, Eleonor Avenido-Cervantes, Darren Gray, Mary Lorraine Mationg, Donald P McManus, Thomas G Egwang, et al. Development of a latex microsphere-based lateral flow immunoassay for the diagnosis of schistosomiasis japonica. PLoS neglected tropical diseases. 2024. 18. 12. e0012742
Hiroshi Yamasaki, Hiromu Sugiyama, Yasuyuki Morishima, Yasuhito Sako. Molecular identification of Spirometra infections in companion animals and wildlife in Japan. The Journal of veterinary medical science. 2024. 86. 4. 409-412

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MISC (15)：

A. Ito, Y. Sako, T. Yanagida, M. Nakao, M. Okamoto. Lethal cestode zoonoses, cysticercosis and echinococcoses in Asia and the World. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 2013. 42. S4-S4
Akira Ito, Minoru Nakao, Yasuhito Sako. Echinococcosis: serological detection of patients and molecular identification of parasites. FUTURE MICROBIOLOGY. 2007. 2. 4. 439-449
Hiroshi Yamasaki, Kazuhiro Nakaya, Minoru Nakao, Yasuhito Sako, Akira Ito. Significance of Molecular Diagnosis using Histopathological Specimens in Cestode Zoonoses. Tropical Medicine and Health. 2007. 35. 4. 307-321
T Ikejima, ZX Piao, Y Sako, MO Sato, S Bao, R Si, F Yu, CL Zhang, M Nakao, H Yamasaki, et al. Evaluation of clinical and serological data from Taenia solium cysticercosis patients in eastern Inner Mongolia Autonomous Region, China. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE. 2005. 99. 8. 625-630
Paron Dekumyoy, Jitra Waikagul, Sirivan Vanijanonta, Malinee Thairungroj, Minoru Nakao, Yasuhito Sako, Sonoyo Watanabe, Akira Ito. Cysticercosis: IgG-ELISA evaluations of peak1 antigen and <30 kDa antigen of delipidized extract of Taenia solium metacestodes. Southeast Asian Journal of Tropical Medicine and Public Health. 2004. 35. 1. 1-9

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Patents (1)：

嚢虫症診断用抗原の精製方法(日本)

Books (10)：

近年話題になっている新興・再興感染症・One Healthとしての感染症:エキノコックス症
北海道医師会 2025
コンパクト微生物学(寄生虫)
南江堂 2021
シンプル微生物学(原虫学・蠕虫学)
南江堂 2018
エキノコックス症(単包条虫症、多包条虫症)
医薬ジャーナル社 2016
有鉤嚢虫症の免疫検査抗原の簡便な精製法
三恵社 2014

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Lectures and oral presentations (31)：

Community Level Application of eDNA Surveillance System:Assessing & Mapping the Temporality of Schistosomiasis in Ekiran, Leyte, Philippines
(2025)
多包虫症の新規検査法の標的としての宿主血中循環セルフリーDNAの評価
(第94回寄生虫学会大会 2025)
Soil eDNA opening new insights in O.h.quadrasi distribution and S. japonicum environmental presence in a community level
(2025)
Seasonality of schistosomiasis infection risk and the dynamics of environmental DNA detection
(21st International Congress for Tropical Medicine and Malaria (ICTMM2024) 2024)
多包虫由来物質がヒトの肝細胞に及ぼす影響の解明
(第93回日本寄生虫学会大会)

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Education (5)：

- 1999 Hokkaido University Graduate School, Division of Veterinary Medicine
- 1999 Hokkaido University
- 1999 Hokkaido University Graduate School, Division of Veterinary Medicine
- 1995 Hokkaido University Faculty of Veterinary Medicine Veterinary Medicine
- 1995 Hokkaido University Faculty of Veterinary Medicine

Professional career (2)：

博士(獣医学) (北海道大学)
博士(医学) (旭川医科大学)

Awards (1)：

2006/05 - 日本寄生虫学会第15回日本寄生虫学会奨励賞

Association Membership(s) (7)：

日本獣医寄生虫学会 , 日本熱帯医学会 , 日本臨床寄生虫学会 , 日本臨床寄生虫学会 , 日本熱帯医学会 , 日本獣医学会 , 日本寄生虫学会

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