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J-GLOBAL ID：200901014780305931 Update date: Sep. 19, 2024

HIRAKU Yusuke

ヒラクユウスケ | HIRAKU Yusuke

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Affiliation and department：
Job title： Professor

Research field (3)： Hygiene and public health (non-laboratory) , Hygiene and public health (laboratory) , Healthcare management, medical sociology

Research keywords (2)：衛生学 , Hygiene

Research theme for competitive and other funds (10)：

2023 - 2027 加熱式たばこの次世代影響:生体試料のマルチオミックス解析に基づく分子疫学研究
2020 - 2023 加熱式たばこによる低出生体重のリスクを評価する分子疫学研究
2018 - 2021 粒子状物質による健康影響におけるDAMPの役割の解明とリスク評価法の開発
2017 - 2020 喫煙に起因する低体重出生のリスクを予測するマイクロRNAの探索と役割の解明
感染・炎症による発がん機構の解析

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Papers (9)：

Li Y, Li M, Ahmed K, Yang J, Song L, Cui ZG, Hiraku Y. Mechanistic Study of Macranthoside B Effects on Apoptotic Cell Death in Human Cervical Adenocarcinoma Cells. Folia Biol (Praha). 2023. 68. 5-6. 189-200
平工雄介. 産業保健における学術研究の役割と今後の課題 ~化学物質による健康障害を例に~. 産業医学ジャーナル. 2022. 45. 5. 72-73
Sawa S, Hashizume K, Abe T, Kusaka Y, Fukazawa Y, Hiraku Y, Hagihara A. Pathway linking physical activity, sleep duration, and breakfast consumption with the physical/psychosocial health of schoolchildren. J Child Health Care. J Child Health Care. 2021. 25. 1. 5-17
Mizutani H, Shiga C, Imai M, Ikemura K, Kitamura Y, Ohta K, Miyazawa D, Sakanashi M, Tahira T, Maeda T, et al. Idarubicin, an anthracycline, induces oxidative DNA damage in the presence of copper (II). Anticancer Res. 2020. 40. 10. 5399-5404
Sawa S, Sekine M, Yamada M, Fukazawa Y, Hiraku Y. Social and family factors as determinants of exercise habits in Japanese elementary school children: a cross-sectional study from the Super Shokuiku School Project. Environ Health Prev Med. 2020. 25. 1. 54-54

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MISC (23)：

Yu-Lin Li, De-Jun Zhou, Zheng-Guo Cui, Lu Sun, Qian-Wen Feng, Shahbaz Ahmad Zakki, Yusuke Hiraku, Cheng-Ai Wu, Hidekuni Inadera. The molecular mechanism of a novel derivative of BTO-956 induced apoptosis in human myelomonocytic lymphoma cells. Apoptosis. 2021. 26. 3. 219-231
S Oikawa, Y Hiraku, T Fujiwara, Saito, I, S Kawanishi. Site-specific hydroxylation at polyguanosine in double-stranded DNA by nickel(II) in the presence of SH compounds: Comparison with singlet oxygen-induced DNA damage. CHEMICAL RESEARCH IN TOXICOLOGY. 2002. 15. 8. 1017-1022
S Homma-Takeda, Y Hiraku, Y Ohkuma, S Oikawa, M Murata, K Ogawa, T Iwamuro, S Li, GF Sun, Y Kumagai, et al. 2,4,6-trinitrotoluene-induced reproductive toxicity via oxidative DNA damage by its metabolite. FREE RADICAL RESEARCH. 2002. 36. 5. 555-566
Catechol and hydroquinone have different redox properties for their differential DNA-damaging activity (共著) . Chem. Res. Toxicol. 2002. 15, 76-82
Metabolism of carcinogenic urethane to nitric oxide is involved in oxidative DNA damage (共著). Free Radic.Biol. Med. 2002. 33(5), 703-714

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Books (1)：

図解腫瘍薬学
南山堂 2020

Lectures and oral presentations (18)：

細胞内分子動態のイメージング解析に基づくダイオキシン標的ニューロンの同定
(第94回日本衛生学会学術総会 2024)
オルト-トルイジン代謝物による膀胱上皮細胞におけるニトロ化DNA損傷
(第94回日本衛生学会学術総会 2024)
タウリンは老化促進モデルマウス脳のベータ-アミロイドとリン酸化タウの沈着を抑制する
(第94回日本衛生学会学術総会 2024)
新型コロナウイルス感染症罹患後症状に対し休復職支援を行った4例、
(第66回日本産業衛生学会北陸甲信越地方会総会 2023)
環境因子による発がんとDNA損傷:これまでの研究の歩み
(日本衛生学会若手の会夏の集い 2023)

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Education (4)：

- 1998 Kyoto University
- 1998 Kyoto University Graduate School, Division of Medicine
- 1994 Kyoto University Faculty of Medicine
- 1994 Kyoto University Faculty of Medicine

Professional career (1)：

M.D. Ph.D. (Kyoto University)

Work history (4)：

2006 - 現在 Mie University Graduate School of Medicine
2000 - 現在 Research Associate, Mie University School of Medicine
2005 - 2006 Mie University Graduate School of Medicine
2000 - 2005 Mie University Faculty of Medicine

Association Membership(s) (14)：

日本光医学・光生物学会 , 日本酸化ストレス学会 , 日本生化学会 , 日本癌学会 , 日本産業衛生学会 , 日本衛生学会 , 日本公衆衛生学会 , 北陸公衆衛生学会 , 日本DOHaD学会 , 分子予防環境医学研究会 , 日本環境変異原学会 , 日本内分泌撹乱化学物質学会(環境ホルモン学会) , 環境ホルモン学会 , 日本NO学会

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