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J-GLOBAL ID：200901015202338998 Update date: Apr. 12, 2025

Uraguchi Shimpei

ウラグチシンペイ | Uraguchi Shimpei

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Affiliation and department：
Job title： Senior assistant professor
Homepage URL (1)： http://www.pharm.kitasato-u.ac.jp/kouei/

Research field (2)： Plant nutrition, soil science , Environmental load reduction/restoration technology

Research keywords (6)：分子育種 , 栄養輸送 , 金属蓄積 , 植物 , Metal accumulation , Plant

Research theme for competitive and other funds (7)：

2024 - 2027 有害金属に対する根の「積極的な伸長停止戦略」とNAC型転写因子の役割の解析
2023 - 2025 Verifying the hypothesis of chromatin platform construction by boron in plants
2021 - 2024 植物の根端メリステムに対する有害金属毒性としてのDNA損傷の検証
2018 - 2021 Molecular analysis of toxic metal detoxification in the root apical meristem
2016 - 2018 Molecular breeding for controlling long-distance transport of toxic and nutritional elements in plants

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Papers (68)：

Yasukazu Takanezawa, Kazuma Sakai, Ryosuke Nakamura, Yuka Ohshiro, Shimpei Uraguchi, Masako Kiyono. The predominant role of p62/SQSTM1 over NBR1 in methylmercury-induced cytotoxicity and cellular defense. Biochemical and Biophysical Research Communications. 2025
Shimpei Uraguchi, Masakazu Sato, Chihiro Hagai, Momoko Hirakawa, Kotomi Ogawa, Miyu Odagiri, Haruka Sato, Ayaka Ohmori, Yuka Ohshiro, Ryosuke Nakamura, et al. Phenylmercury stress induces root tip swelling through auxin homeostasis disruption. Plant Molecular Biology. 2025
Midori Tabara, Shimpei Uraguchi, Masako Kiyono, Izumi Watanabe, Atsushi Takeda, Hideki Takahashi, Toshiyuki Fukuhara. A resilient mutualistic interaction between cucumber mosaic virus and its natural host to adapt to an excess zinc environment and drought stress. Journal of plant research. 2024
Ryosuke Nakamura, Takashi Iwai, Yasukazu Takanezawa, Tatsuya Shirahata, Naruki Konishi, Yuka Ohshiro, Shimpei Uraguchi, Mitsuo Tanabe, Yoshinori Kobayashi, Kenji Sakamoto, et al. Oleanolic acid-3-glucoside, a synthetic oleanane-type saponin, ameliorates methylmercury-induced dysfunction of synaptic transmission in mice. Toxicology. 2024. 506. 153867-153867
Shimpei Uraguchi, Yuka Ohshiro, Kaede Abe, Yuta Tsuchiya, Ryosuke Nakamura, Yasukazu Takanezawa, Masako Kiyono. Root cell-type specific expressions of bacterial mercury transporter MerC and plant SNARE SYP121 fusion protein differentially affect cadmium accumulation patterns of Arabidopsis. SOIL SCIENCE AND PLANT NUTRITION. 2023

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MISC (146)：

大橋悠暉, 高根沢康一, 酒井和真, 中村亮介, 大城有香, 浦口晋平, 清野正子. Autophgy response to toxic metal exposure in SH-SY5Y neuroblastoma cells. 衛生薬学・環境トキシコロジー講演要旨集. 2023. 2023
高根沢康一, 柏野結, 中村亮介, 大城有香, 浦口晋平, 清野正子. Effect of autophagy on methylmercury-induced lipid droplet formation and adipokine expression in 3T3-L1 cells. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
佐藤正和, 浦口晋平, 萬代麻衣, 大城有香, 中村亮介, 高根沢康一, 清野正子. 亜ヒ酸とカドミウム毒性に対するシロイヌナズナ根端分裂組織の応答の特異性. 日本土壌肥料学会講演要旨集(Web). 2023. 69
浦口晋平, 山村有加, 菅谷翔, 佐藤正和, 大城有香, 中村亮介, 高根沢康一, 清野正子. 根端分裂組織のカドミウム・亜ヒ酸応答におけるNAC型転写因子ANAC044とANAC085の機能分化の可能性. 日本土壌肥料学会講演要旨集(Web). 2023. 69
土屋佑太, 浦口晋平, 月岡輝璃, 西田翔, 大城有香, 中村亮介, 高根沢康一, 清野正子. 微生物由来の金属輸送体MerC多重発現シロイヌナズナの確立の試み. 日本土壌肥料学会講演要旨集(Web). 2023. 69

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Lectures and oral presentations (20)：

Organ accumulation of gadolinium contrast agents in mice
(日本薬学会年会要旨集(Web) 2021)
Role of cysteine residues in mercury transport by the mercury transporter MerT
(日本薬学会年会要旨集(Web) 2021)
p62/SQSTM1 attenuates MeHg-induced endoplasmic reticulum stress
(日本薬学会年会要旨集(Web) 2021)
Establishment of quantitative PCR-based Arabidopsis DNA-damage assay
(日本植物生理学会年会(Web) 2021)
根端分裂組織の有害元素応答におけるSOG1,ANAC044,ANAC085の役割
(日本土壌肥料学会講演要旨集(Web) 2021)

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Education (3)：

- 2007 Tokyo University of Agriculture and Technology
- 2004 Tokyo University of Agriculture and Technology
- 2002 Tokyo University of Agriculture and Technology Faculty of Agriculture Department of Environmental and Natural Resource Sciences

Professional career (1)：

博士(農学) (東京農工大学)

Work history (7)：

2025/04 - 現在 Chiba University Plant Nutrition Lab Associate professor
2015/04 - 現在 Kitasato University School of Pharmaceutical Sciences
2025/04 - 2026/03 北里大学薬学部公衆衛生学教室特任准教授(クロスアポイントメント)
2013/04 - 2015/03 JSPS Postdoctoral Fellow for Abroad University of Bayreuth, Department of Plant Physiology
2010/04 - 2013/03 JSPS Postdoctoral Fellow (PD) Graduate School of Agricultural and Life Sciences

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Committee career (4)：

2024/04 - 現在日本土壌肥料学会和文誌「日本土壌肥料学雑誌」常任編集委員(植物栄養分野)
2021/05 - 現在 Frontiers in Plant Science Associate Editor
2008/06 - 現在日本トランスポーター研究会幹事
2019/09 - 2021/05 Frontiers in Plant Science Review Editor

Association Membership(s) (5)：

日本土壌肥料学会 , 日本植物生理学会 , 日本農芸化学会 , 日本トランスポーター研究会 , American Society of Plant Physiologist

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