2014 - 2018 Study on effects of modified mTOR activities under hypoxia and nutrient starvation on radiation sensitivity of cancer cells.
2014 - 2017 NSAIDs diclofenac, indomethacin, and meloxicam highly upregulate expression of ICAM-1 and COX-2 induced by X-irradiation in human endothelial cells
2011 - 2013 Radiosensitization of radioresistant cancer stem cells by inhibition of ATM
2000 - 2002 Inhibition of DNA-PK activity by phosphorothioate oligonucleotides
2001 - 2001 DNA依存性プロテインキナーゼを利用した放射線感受性予測と放射線増感
1998 - 1999 Study to control radiation lung damages.
1997 - 1998 Effect of a phosphatidylinositol 3-kinase inhibitor wortmannin on radiation and bleomycin sensitivities.
1996 - 1996 アンチセンスKup70/80DNAを用いた放射線遺伝子治療
1996 - 1996 皮膚における紫外線誘発突然変異
1996 - 1996 アンチセンスATM遺伝子治療による放射線増感効果
1995 - 1995 ヒト腫瘍の放射線感受性因子としてのATDC遺伝子発現の関与
1992 - 1993 A search of methods to enhance the capacity to resist against radiation-induced acute injuries.
放射線腫瘍学
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Papers (94):
Yusuke Urushihara, Takuma Hashimoto, Yohei Fujishima, Yoshio Hosoi. AMPK/FOXO3a Pathway Increases Activity and/or Expression of ATM, DNA-PKcs, Src, EGFR, PDK1, and SOD2 and Induces Radioresistance under Nutrient Starvation. International Journal of Molecular Sciences. 2023. 24. 16. 12828-12828
Masaki Fujisawa, Yoshihiro Haga, Masahiro Sota, Mitsuya Abe, Yuji Kaga, Yohei Inaba, Masatoshi Suzuki, Taiichiro Meguro, Yoshio Hosoi, Koichi Chida. Evaluation of Lens Doses among Medical Staff Involved in Nuclear Medicine: Current Eye Radiation Exposure among Nuclear-Medicine Staff. Applied Sciences. 2023. 13. 16. 9182-9182
Hidetoshi Satoh, Shintaro Ochi, Kosuke Mizuno, Yutaka Saga, Shohei Ujita, Miyu Toyoda, Yuichi Nishiyama, Kasumi Tada, Yosuke Matsushita, Yuichi Deguchi, et al. Design, synthesis and biological evaluation of 2-pyrrolone derivatives as radioprotectors. Bioorganic & Medicinal Chemistry. 2022. 67. 116764-116764
Takuma Hashimoto, Yusuke Urushihara, Yasuhiko Murata, Yohei Fujishima, Yoshio Hosoi. AMPK increases expression of ATM through transcriptional factor Sp1 and induces radioresistance under severe hypoxia in glioblastoma cell lines. Biochemical and biophysical research communications. 2022. 590. 82-88
Akinori Morita, Shintaro Ochi, Hidetoshi Satoh, Shohei Ujita, Yosuke Matsushita, Kasumi Tada, Mihiro Toyoda, Yuichi Nishiyama, Kosuke Mizuno, Yuichi Deguchi, et al. A Novel RNA Synthesis Inhibitor, STK160830, Has Negligible DNA-Intercalating Activity for Triggering A p53 Response, and Can Inhibit p53-Dependent Apoptosis. Life (Basel, Switzerland). 2021. 11. 10
A. K. Putra, K. Tanimoto, E. Hiyama, M. Nishiyama, Y. Hosoi, K. Hiyama. EXPLORATION OF THE GENES ASSOCIATED WITH CELLULAR IMMORTALIZATION IN LUNG CANCER. RESPIROLOGY. 2011. 16. 151-151
2013/04 - 現在 Tohoku University International Research Institute of Disaster Science
Association Membership(s) (5):
放射線腫瘍学会生物部会
, Japanese Association for Radiation Accident/Disaster Medicine
, THE JAPANESE RADIATION RESEARCH SOCIETY
, JAPANESE SOCIETY FOR RADIATION ONCOLOGY
, JAPAN RADIOLOGICAL SOCIETY