Research theme for competitive and other funds (9):
2022 - 2025 Elucidation of pathogenesis of interactable lung diseases associated with dysregulated lipid metabolism
2020 - 2023 複合的オミクス解析を用いて探る、肺胞微石症の分子病態と新規治療法の開発
2019 - 2022 The quality of lipid component of pulmonary surfactant in lung diseases
2016 - 2019 Elucidating the mechanism of construction of intratumor heterogeneity by tumor-associated glycan
2013 - 2016 Studies of pulmonary surfactant proteins on new aspects of host defense functions: anti-tumor activity and defensive activity against disease development.
2013 - 2016 Regulation of tumor microenvironment by tumor-associated sialyl-Tn antigen
2010 - 2012 Analysis of Nucleotide sugar: Association with pathogenesis of COPD in Leukocyte
2008 - 2009 The Metabolome Analysis: Association with pathogenesis of COPD in Leukocyte
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Papers (38):
Tetsuya Hirabayashi, Mai Kawaguchi, Sayaka Harada, Misa Mouri, Rina Takamiya, Yoshimi Miki, Hiroyasu Sato, Yoshitaka Taketomi, Kohei Yokoyama, Tetsuyuki Kobayashi, et al. Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups. Cell reports. 2023. 42. 2. 111940-111940
Makoto Murakami, Rina Takamiya, Yoshimi Miki, Nao Sugimoto, Yuki Nagasaki, Toshiko Suzuki-Yamamoto, Yoshitaka Taketomi. Segregated functions of two cytosolic phospholipase A2 isoforms (cPLA2α and cPLA2ε) in lipid mediator generation. Biochemical pharmacology. 2022. 203. 115176-115176
Luyiyun Liang, Rina Takamiya, Yoshimi Miki, Kanako Heike, Yoshitaka Taketomi, Nao Sugimoto, Midori Yamaguchi, Hiroshi Shitara, Yasumasa Nishito, Tetsuyuki Kobayashi, et al. Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti-inflammatory lipid N-acylethanolamine. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022. 36. 5. e22301
2011/09 - 5th SFRR-Asia, 8th ASMRM, and 11th J-mit Young Investigator Award Regulation of monocyte function by tumor associated sialyl-Tn antigen through ROS production
2010/06 - The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide Travel Award High mobility group A1 protein mediates human nitric oxide synthase 2 gene expression.