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J-GLOBAL ID：200901017245867806   Update date: Feb. 12, 2025

yanagi shigeru

yanagi shigeru
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Affiliation and department：
Gakushuin University Faculty of Science Department of Life Science

About Gakushuin University Faculty of Science Department of Life Science


Other affiliations (1)：
  • Tokyo University of Pharmacy and Life Sciences
Homepage URL  (1)： http://www.ls.toyaku.ac.jp/Life-Science/lmb-8/
Research field  (6)： Medical biochemistry ,  Pathobiochemistry ,  Cell biology ,  Functional biochemistry ,  Neuroscience - general ,  Molecular biology
Research keywords  (33)： MITOL ,  ユビキチン化 ,  ユビキチンリガーゼ ,  ミトコンドリア ,  小胞体ストレス ,  シグナル伝達 ,  活性酸素種 ,  脳神経 ,  CRAG ,  CAMDI ,  CRAM ,  Syk ,  ポリグルタミン病 ,  GTPase活性 ,  GTP結合蛋白質 ,  脳神経疾患 ,  CD45 ,  p72syk ,  Lyn ,  チロシンキナ-ゼ ,  セマフォリン ,  Axon Pruning ,  Filopodia ,  血小板 ,  PI 3 kinase ,  蛋白質 ,  細胞増殖 ,  細胞移動 ,  インタ-ロイキン2 ,  チロシンホスファタ-ゼ ,  血管内皮細胞 ,  包括脳ネットワーク ,  統合脳・統合脳
Papers (100)：
  • Isshin Shiiba, Naoki Ito, Hijiri Oshio, Yuto Ishikawa, Takahiro Nagao, Hiroki Shimura, Kyu-Wan Oh, Eiki Takasaki, Fuya Yamaguchi, Ryoan Konagaya, et al. ER-mitochondria contacts mediate lipid radical transfer via RMDN3/PTPIP51 phosphorylation to reduce mitochondrial oxidative stress. Nature communications. 2025. 16. 1. 1508-1508
  • Motoi Tanabe, Yuga Saito, Ayaka Takasaki, Keita Nakano, Shunta Yamamoto, Chikako Suzuki, Nao Kawamura, Aki Hattori, Mami Oikawa, Shun Nagashima, et al. Role of immature choroid plexus in the pathology of model mice and human iPSC-derived organoids with autism spectrum disorder. Cell reports. 2024. 44. 1. 115133-115133
  • Hiroki Shimura, Sota Yamamoto, Isshin Shiiba, Mami Oikawa, Shohei Uchinomiya, Akio Ojida, Shigeru Yanagi, Hisae Kadowaki, Hideki Nishitoh, Toshifumi Fukuda, et al. Etomoxir suppresses the expression of PPARgamma2 and inhibits the thermogenic gene induction of brown adipocytes through pathways other than β-oxidation inhibition. Journal of biochemistry. 2024
  • Wenjuan Ma, Shah Adil Ishtiyaq Ahmad, Michihiro Hashimoto, Ahad Khalilnezhad, Miho Kataoka, Yuichiro Arima, Yosuke Tanaka, Shigeru Yanagi, Terumasa Umemoto, Toshio Suda. MITOL deficiency triggers hematopoietic stem cell apoptosis via ER stress response. The EMBO Journal. 2024. 43. 3. 339-361
  • Shun Nagashima, Naoki Ito, Isshin Shiiba, Hiroki Shimura, Shigeru Yanagi. Ubiquitin-mediated mitochondrial regulation by MITOL/MARCHF5 at a glance. The Journal of Biochemistry. 2022. 173. 1. 1-11
ｍore...
MISC (31)：
ｍore...
Books (5)：
  • ミトコンドリア疾患治療の新時代 : オルガネラ動態を紐解き異常ミトコンドリアの標的分子を狙う!
    羊土社 2023 ISBN:9784758104098
  • ミトコンドリアダイナミクス : 機能研究から疾患・老化まで
    エヌ・ティー・エス 2021 ISBN:9784860437466
  • ミトコンドリアと疾患・老化 : 細胞内代謝プラントとしての役割を知り, ミトコンドリアを標的とした創薬に挑む
    羊土社 2019 ISBN:9784758103800
  • 「特集」ミトコンドリアのヒト疾患学 : Common Diseaseに応じて変化する代謝・品質管理と病態制御メカニズム
    羊土社 2012 ISBN:9784758100847
  • 未来の治療に向かって : 生命医科学の挑戦
    東京化学同人 2010 ISBN:9784807912889
Professional career (1)：
  • 博士(医学) (神戸大学)
Work history (10)：
  • 2020 - 現在 Gakushuin University Faculty of Science Department of Life Science
  • 2020 - 現在 Tokyo University of Pharmacy and Life Sciences
  • 2020/04 - 2021/03 Tokyo University of Pharmacy and Life Sciences School of Life Science
  • 2005 - 2020 Tokyo University of Pharmacy and Life Sciences School of Life Science
  • 2002 - 2006 科学技術振興事業団 戦略的創造研究推進事業 さきがけ研究21 研究員(併任)
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Awards (1)：
  • 2004 - 日本生化学会 奨励賞
Association Membership(s) (6)：
THE JAPANESE CANCER ASSOCIATION ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE JAPANESE SOCIETY OF MITOCHONDRIAL RESEARCH AND MEDICINE ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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