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J-GLOBAL ID：200901019119070288   Update date: Feb. 07, 2024

TAKAKO SHOSAKU

シヨウサク タカコ | TAKAKO SHOSAKU
Affiliation and department：
Hokuriku University Faculty of Health and Medical Sciences

About Hokuriku University Faculty of Health and Medical Sciences


Job title： Professor
Homepage URL  (1)： http://yoneda-lab.w3.kanazawa-u.ac.jp/index.html
Research field  (3)： Clinical pharmacy ,  Physiology ,  Neuroscience - general
Research keywords  (5)： motor learning ,  thalamic reticular nucleus ,  hippocampal neuron ,  endocannabinoid ,  Physiology in General Neuro and Musculer Physiology
Research theme for competitive and other funds  (23)：
  • 2019 - 2023 Basic research for rehabilitation: a focus on roles of basal ganglia and cerebellum in behavioral flexibility
  • 2019 - 2022 Examination of the thalamic reticular nucleus dysfunction hypothesis of schizophrenia
  • 2017 - 2020 嗜好食品による抗老化と認知機能促進の分子基盤及び機能的形態学的機序の解明
  • 2016 - 2018 リハビリテーション技術確立のための運動学習における行動柔軟性に関する基礎研究
  • 2013 - 2017 シナプスにおける逆行性シグナルが生後発達期の機能的神経回路形成に果たす役割の解明
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Papers (84)：
  • Takako Ohno-Shosaku, Mitsugu Yoneda, Takashi Maejima, Mohan Wang, Yui Kikuchi, Kaito Onodera, Yuji Kanazawa, Chitoshi Takayama, Michihiro Mieda. Action sequence learning is impaired in genetically modified mice with the suppressed GABAergic transmission from the thalamic reticular nucleus to the thalamus. Neuroscience. 2023
  • Tetsuo Ota, Yui Kikuchi, Ikumi Amiya, Takako Ohno-Shosaku, Yasuharu Koike, Mitsugu Yoneda. Evaluation of motor learning in predictable loading task using a force sense presentation device. Experimental Brain Research. 2022. 240. 12. 3305-3314
  • Yui Kikuchi, Mitsugu Yoneda, Kyoko Nishikawa, Tsukika Noda, Honoka Hasegawa, Tomoaki Fujisaku, Takako Ohno-Shosaku. Effects of environmental enrichment on exploratory behavior, win-stay and lose-shift performance, motor sequence learning, and reversal learning during the three-lever operant task in mice. Behavioural brain research. 2022. 429. 113904-113904
  • Shoji Tanaka, Naotoshi Sugimoto, Takako Ohno-Shosaku, Sachiko Madokoro, Pleiades Tiharu Inaoka, Toshiaki Yamazaki. Effects of long-term treatment with dietary theobromine on rat skeletal muscles. Molecular biology reports. 2022. 49. 5. 3965-3973
  • Hayate Tanigami, Mitsugu Yoneda, Yuki Tabata, Ryosuke Echigo, Yui Kikuchi, Maya Yamazaki, Yasushi Kishimoto, Kenji Sakimura, Masanobu Kano, Takako Ohno-Shosaku. Endocannabinoid Signaling from 2-Arachidonoylglycerol to CB1 Cannabinoid Receptor Facilitates Reward-based Learning of Motor Sequence. Neuroscience. 2019. 421. 1-16
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MISC (31)：
  • Naotoshi Sugimoto, Masanori Katakura, Kentaro Matsuzaki, Takako Ohno-Shosaku, Akihiro Yachie, Osamu Shido. Theobromine, the primary methylxanthine found in Theobroma cacao, can pass through the blood-brain barrier in mice. FASEB JOURNAL. 2016. 30
  • Ryousuke Echigo, Naotoshi Sugimoto, Akihiro Yachie, Takako Ohno-Shosaku. Cannabinoids prevent TLR2-induced inflammation via CB1 receptor in human glioblastoma cells. NEUROSCIENCE RESEARCH. 2011. 71. E197-E197
  • Yuto Sugawara, Chiho Muranishi, Keisuke Nagasawa, Takako Ohno-Shosaku. N-desmethylclozapine, a metabolite of the antipsychotic clozapine, modulates excitatory and inhibitory signals oppositely by acting on M1 muscarinic and GABA(A) receptors in hippocampal neurons. NEUROSCIENCE RESEARCH. 2011. 71. E298-E299
  • Ryoko Watanabe, Mitsugu Yoneda, Yui Kikuchi, Takako Ohno-Shosaku. Comparison of the performance on three-lever operant task between control and Parkinson's model rats. NEUROSCIENCE RESEARCH. 2011. 71. E140-E140
  • Yuki Hashimotodani, Takako Ohno-Shosaku, Asami Tanimura, Masanobu Kano. Molecular mechanisms for the induction of retrograde endocannabinoid signaling. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2010. 60. S47-S47
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Lectures and oral presentations  (25)：
  • 3 レバー・オペラント課題における学習効率と行動柔軟性:カンナビノイド系とテオブロミン
    (第12回日本作業療法研究学会学術大会 2018)
  • The performance of aged mice in 1-lever, 3-lever, and reverse 3-lever operant task
    (2018)
  • The relationship between prediction-based feedforward motor control during loading task and motor learning during lever pressing task
    (2018)
  • 運動学習および行動柔軟性に影響をおよぼす因子:カンナビノイド系とテオブロミン
    (第95回日本生理学会大会 2018)
  • 3レバーオペラント課題における2-AG合成酵素DGLα欠損マウスの適応行動の障害
    (39回 日本生物学的精神医学会・第47回 日本神経精神薬理学会 合同年会 2017)
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Education (3)：
  • 1981 - 1985 Kyoto University Graduate School, Division of Medicine
  • 1979 - 1981 Osaka University
  • 1975 - 1979 Kanazawa University
Professional career (2)：
  • 医学博士 (京都大学)
  • 医科学修士 (大阪大学)
Work history (7)：
  • 2023/04 - 現在 Hokuriku University Faculty of Health and Medical Sciences Professor
  • 2005/04 - 2022/03 Kanazawa University Faculty of Health Sciences
  • 1996/12 - 2005/03 Kanazawa University Graduate School of Medical Science
  • 1994/07 - 1996/11 Kanazawa University Faculty of Medicine
  • 1991/04 - 1994/06 Kanazawa University Faculty of Medicine
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Committee career (2)：
  • 2007 - -: Physiol. Soc. Japan
  • 2007 - 日本生理学会 常任幹事
Association Membership(s) (2)：
The Japan Neuroscience Society ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN
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