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J-GLOBAL ID：200901020449262203 Update date: Nov. 22, 2024

Sato Ken

サトウケン | Sato Ken

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://traffic.dept.med.gunma-u.ac.jp/

Research field (3)： Molecular biology , Developmental biology , Cell biology

Research keywords (8)： Membrane Traffic , Fertilization , Organelle , 発生 , 膜 , 輸送 , タンパク質 , protein transport membrane development

Research theme for competitive and other funds (18)：

2020 - 2025 Analysis of sperm-oocyte membrane fusion regulator in animal fertilization
2019 - 2024 動物発生における細胞膜分解の分子機構とその生理機能
2017 - 2020 低分子量GTPase Rabとその新規GDP/GTP交換因子ファミリーの機能解明
2017 - 2019 巨大リポタンパク質粒子の生合成・分泌機構
2014 - 2017 受精卵における細胞内膜系リモデリングの時空間的制御機構の解明

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Papers (88)：

Yuhkoh Satouh, Takaki Tatebe, Isei Tanida, Junji Yamaguchi, Yasuo Uchiyama, Ken Sato. Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition. bioRxiv. 2024
Taeko Sasaki, Yasuharu Kushida, Takuya Norizuki, Hidetaka Kosako, Ken Sato, Miyuki Sato. ALLO-1- and IKKE-1-dependent positive feedback mechanism promotes the initiation of paternal mitochondrial autophagy. Nature Communications. 2024. 15. 1
Ichiro Kawasaki, Kenta Sugiura, Taeko Sasaki, Noriyuki Matsuda, Miyuki Sato, Ken Sato. MARC-3, a membrane-associated ubiquitin ligase, is required for fast polyspermy block in Caenorhabditis elegans. Nature Communications. 2024. 15. 1
Yuhkoh Satouh, Emiko Suzuki, Keisuke Sasaki, Ken Sato. Improved mRNA electroporation into immature oocytes to examine protein dynamics during development. 2023
Ikuko Maejima, Taichi Hara, Satoshi Tsukamoto, Hiroyuki Koizumi, Takeshi Kawauchi, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, Inoya Isobe, Kazuo Emoto, et al. RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution. Communications Biology. 2023. 6. 1

MISC (17)：

Books (4)：

Lectures and oral presentations (81)：

低分子量GTPase Rab35の神経発生における機能解析
(第43回日本分子生物学会 2020)
グリシントランスポーターであるGlyt1aは胚発生に伴いRab5/Rab7陽性エンドソームを介してエンドサイトーシスされ分解される
(第38回日本受精着床学会総会・学術講演会 2020)
初期胚発生におけるリソソーム分解系を介した細胞膜成分リモデリング機構
(第93回日本生化学会大会 2020)
膵β細胞において SFT-4/Surf4 は新生プロインスリンの小胞体からの輸送を制御する
(第93回日本内分泌学会学術総会 2020)
The mechanism underlying selective elimination of paternal mitochondria in C. elegans
(The 72nd Annual Meeting of the Japan Society for Cell Biology 2020)

Education (3)：

- 1997 The University of Tokyo Graduate School of Science Department of Biological Sciences, Ph. D.
- 1994 The University of Tokyo Graduate School of Science Department of Biological Sciences, Master of Sciences
- 1992 Kyushu University Faculty of Sciences Department of Biology

Professional career (1)：

Work history (10)：

2019/04 - 現在 Institute for Molecular and Cellular Regulation Director
2016/04 - 現在 Gunma University Institute for Molecular and Cellular Regulation
2010/02 - 現在 Gunma University Institute for Molecular and Cellular Regulation
2004/10 - 2010/01 Gunma University Institute for Molecular and Cellular Regulation
1998/04 - 2004/10 理化学研究所研究員

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Awards (3)：

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