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J-GLOBAL ID：200901022351326370 Update date: Apr. 04, 2025

Yasutoshi Tatsumi

タツミヤストシ | Yasutoshi Tatsumi

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Affiliation and department：
Job title： Senior Researcher
Homepage URL (1)： https://www.pref.chiba.lg.jp/gan/kenkyujo/shoni-nanchi.html

Research field (4)： Genomics , Cell biology , Molecular biology , Genetics

Research keywords (19)：小児がん , 神経芽腫 , 自然退縮 , 細胞死とがん , p53 , ミトコンドリア異常 , がんのマーカー , ゲノム解析 , 胃癌 , 骨肉腫 , 希少がん , 肉腫 , 難治がん , 膵癌 , マイクロ RNA , オルガノイド , 細胞周期 , RB/E2F , DNA複製

Research theme for competitive and other funds (11)：

2023 - 2026 神経芽腫の悪性化と自然退縮メカニズムの解明
2021 - 2024 胃がんに関連したARID2遺伝子の新規SNP機能解析及びその臨床応用
2020 - 2023 神経芽腫の自然退縮におけるミトコンドリア恒常性の意義とその破綻による悪性化機構
2018 - 2021 Analysis of gastrointestinal cancer risk-related function SNP and its clinical application
2017 - 2021 Genomic analysis for detecting therapeutic targets in clear cell sarcoma

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Papers (24)：

Tatsuya Masuda, Takayoshi Watanabe, Yasutoshi Tatsumi, Jason Lin, Kazuhiro Okumura, Toshinori Ozaki, Hiroshi Sugiyama, Yasuhiko Kamikubo. Cancer Accumulation and Anticancer Activity of "CROX (Cluster Regulation of RUNX)" PIP in HER2-Positive Gastric Cancer Evaluated by Chicken Egg Cancer Model. Cancer medicine. 2025. 14. 7. e70845
Yasutoshi Tatsumi, Tatsuya Masuda, Takayoshi Watanabe, Rohmad Utomo, Ummi Zulfin, Edy Meiyanto, Toshinori Ozaki, Yusuke Suenaga, Yasuhiko Kamikubo. Antitumor effect of curcumin analog on osteosarcoma through the inhibition of p300-mediated histone acetylation. Oncology Reports. 2025. 53. 4. 1-11
Hideki Ikeda, Katsushige Kawase, Tatsuya Nishi, Tomofumi Watanabe, Keizo Takenaga, Takashi Inozume, Takamasa Ishino, Sho Aki, Jason Lin, Shusuke Kawashima, et al. Immune evasion through mitochondrial transfer in the tumour microenvironment. Nature. 2025. 638. 8049. 225-236
Daisuke Hoshi, Emiri Kita, Yoshiaki Maru, Hiroyuki Kogashi, Yuki Nakamura, Yasutoshi Tatsumi, Osamu Shimozato, Kazuyoshi Nakamura, Kentaro Sudo, Akiko Tsujimoto, et al. Derivation of Pancreatic Acinar Cell Carcinoma Cell Line HS-1 as a Patient-derived Tumor Organoid. Cancer Science. 2023. 114. 3. 1165-1179
Yosuke Iwatate, Hajime Yokota, Isamu Hoshino, Fumitaka Ishige, Naoki Kuwayama, Makiko Itami, Yasukuni Mori, Satoshi Chiba, Hidehito Arimitsu, Hiroo Yanagibashi, et al. Transcriptomic analysis reveals high ITGB1 expression as a predictor for poor prognosis of pancreatic cancer. PLOS ONE. 2022. 17. 6. e0268630-e0268630

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MISC (5)：

Takayoshi Watanabe, Tatsuya Masuda, Yasutoshi Tatsumi, Utomo Rohmad, Hiroshi Sugiyama, Meiyanto Edy, Yasuhiko Kamikubo. Evaluation of anti-cancer activity of the inhibitors against RUNX and p300 based on the CAM model. CANCER SCIENCE. 2025. 116. 874-874
Takayoshi Watanabe, Tatsuya Masuda, Yasutoshi Tatsumi, Utomo Rohmad, Zulfin Ummi, Meiyanto Edy, Yoshitaka Hippo, Hiroshi Sugiyama, Yasuhiko Kamikubo. The use of Chorioallantoic membrane from fertilized chicken eggs as an anticancer drug evaluation system. CANCER SCIENCE. 2024. 115. 179-179
巽康年, 増田達哉, 渡部隆義, UTOMO Rohmad Y., UTOMO Rohmad Y., ZULFIN Ummi M., ZULFIN Ummi M., MEIYANTO Edy, 末永雄介, 筆宝義隆, et al. Anti-tumor effect on osteosarcoma cells by curcumin analogs accompanied by histone acetylation inhibition. 日本癌学会学術総会抄録集(Web). 2023. 82nd
増田達哉, 増田達哉, 巽康年, 渡部隆義, 尾崎俊文, 中谷一真, ZULFIN Ummi, 末永雄介, 筆宝義隆, 杉山弘, et al. ”CROX (Cluster Regulation of RUNX)” strategy against MYCN-amplified neuroblastoma through p53-mediated apoptosis. 日本癌学会学術総会抄録集(Web). 2023. 82nd
Nakamura Yohko, Tatsumi Yasutoshi, Okumura Kazuhiro, Takatori Atsushi, Maru Yoshiaki, Yokoi Sana, Ohira Miki, Nabeya Yoshihiro, Fukasawa Satoshi, Katayama Jin, et al. Analysis of non-synonymous genetic variations associated with cancer risk by a prospective cohort study. CANCER SCIENCE. 2018. 109. 767

Work history (12)：

2024/04 - 現在千葉県がんセンター研究所がん治療開発グループ・小児難治がん研究室上席研究員
2023/04 - 2024/03 金沢大学がん進展制御研究所
2022/10 - 2024/03 千葉県がんセンター研究所発がん研究グループ・発がん制御研究部上席研究員
2022/04 - 2022/09 Chiba cancer Center Research Institute
2020/04 - 2022/03 千葉県がんセンター研究所がん予防センター・腫瘍ゲノム研究室上席研究員

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Association Membership(s) (3)：

日本分子生物学会 , 日本癌学会 , 日本がん分子標的治療学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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