Rchr
J-GLOBAL ID：200901022712598044   Update date: Aug. 23, 2024

Ishimura Akihiko

イシムラ アキヒコ | Ishimura Akihiko
Affiliation and department：
Kanazawa University Cancer Research Institute, Cancer Research Institute

About Kanazawa University Cancer Research Institute, Cancer Research Institute


Homepage URL  (1)： http://www.kanazawa-u.ac.jp/~ganken/Genomics/index.html
Research field  (2)： Tumor biology ,  Developmental biology
Research keywords  (4)： 分子生物学 ,  細胞生物学 ,  発生生物学 ,  がん遺伝学
Research theme for competitive and other funds  (7)：
  • 2022 - 2025 Screening of epigenetic regulators relating to drug resistance in EGFR-mutated lung cancer
  • 2019 - 2022 CRISPR/Cas9 screening of epigenetic factors relating to cancer malignancy
  • 2013 - 2016 A novel role of Jmjd5, a candidate cancer-related gene, during mouse embryogenesis
  • 2011 - 2012 Functional analysis of Jmjd5, a candidate cancer-related geneidentified by retroviral insertional mutagenesis
  • 2009 - 2010 Functional analysis of Jmjd5, a candidate tumor suppressor gene, for angiogenesis, hematopoiesis and tumorigenesis.
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Papers (31)：
  • Gerelsuren Batbayar, Akihiko Ishimura, Hanbing Lyu, Sasithorn Wanna-Udom, Makiko Meguro-Horike, Minoru Terashima, Shin-Ichi Horike, Takahisa Takino, Takeshi Suzuki. ASH2L, a COMPASS core subunit, is involved in the cell invasion and migration of triple-negative breast cancer cells through the epigenetic control of histone H3 lysine 4 methylation. Biochemical and biophysical research communications. 2023. 669. 19-29
  • Abdalla Ahmed, Jibran Nehal Syed, Lijun Chi, Yaxu Wang, Carmina Perez-Romero, Dorothy Lee, Etri Kocaqi, Amalia Caballero, Jielin Yang, Quetzalcoatl Escalante-Covarrubias, et al. KDM8 epigenetically controls cardiac metabolism to prevent initiation of dilated cardiomyopathy. Nature cardiovascular research. 2023. 2. 2. 174-191
  • Kusuma Suphakhong, Minoru Terashima, Sasithorn Wanna-Udom, Risa Takatsuka, Akihiko Ishimura, Takahisa Takino, Takeshi Suzuki. m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial-mesenchymal transition of lung cancer cells. The Journal of biological chemistry. 2022. 298. 11. 102554-102554
  • Sasithorn Wanna-Udom, Minoru Terashima, Kusuma Suphakhong, Akihiko Ishimura, Takahisa Takino, Takeshi Suzuki. KDM2B is involved in the epigenetic regulation of TGF-β-induced epithelial-mesenchymal transition in lung and pancreatic cancer cell lines. Journal of Biological Chemistry. 2021. 296. 100213-100213
  • Rong Wang, Tadaaki Yamada, Kenji Kita, Hirokazu Taniguchi, Sachiko Arai, Koji Fukuda, Minoru Terashima, Akihiko Ishimura, Akihiro Nishiyama, Azusa Tanimoto, et al. Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer. Nature communications. 2020. 11. 1. 4607-4607
ｍore...
MISC (1)：
  • Takeshi Suzuki, Minoru Terashima, Shoichiro Tange, Akihiko Ishimura. Roles of histone methyl-modifying enzymes in development and progression of cancer. CANCER SCIENCE. 2013. 104. 7. 795-800
Education (4)：
  • - 2001 Niigata University
  • - 2001 Niigata University Graduate School, Division of Science and Technology
  • - 1996 Niigata University Faculty of Science Department of Biology
  • - 1996 Niigata University Faculty of Science
Professional career (2)：
  • Master of Science (Niigata University)
  • PhD (Science) (Niigata University)
Work history (2)：
  • 2007 - -: - 金沢大学 助教
  • 2007 - -: -, Kanazawa Univ., Assistant Profesor
Association Membership(s) (4)：
日本分子生物学会 ,  日本癌学会 ,  The Molecular Biology Society of Japan ,  The Japanese Cancer Association
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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