Adachi Takahiro

安達貴弘 | Adachi Takahiro

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://tadachiimm.wixsite.com/my-site

Research field (4)： Cell biology , Molecular biology , Food sciences , Immunology

Research keywords (10)：腸管センシング , brain-gut axisis , calcium , signaling , food , nerve , gut , imaging , 免疫学 , Immunology

Research theme for competitive and other funds (22)：

2022 - 2025 舌下免疫で誘導される制御性T細胞の組織間移動によるI型アレルギー抑制機序の解明
2019 - 2022 Neurophysical approach in beneficial physiological changes induced by the specific taste through the axes of digestive tract, brain and peripheral tissues
2016 - 2019 Elucidation of mechanisms underlying multi-organ cooperative regulation by analyzing immune cells migrated from gut to whole body and their functional molecules
2015 - 2018 Visualizatiion of immune responses by 5D intravital imaging
2012 - 2016 maintenance and activation mechanisms of memory B cells

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Papers (77)：

平田悠, 野村和弘, 加藤大輔, 橘吉寿, 内山奏, 細岡哲也, 原雄二, 安達貴弘, 柴崎貢志, 和氣弘明, et al. 不動化における筋量制御のメカニズム. 日本臨床分子医学会学術総会プログラム・抄録集. 2023. 58回. 56-56
Yui Takeuchi, Moe Fukunaga, Shun Iwatani, Kazuhiko Miyanaga, Takahiro Adachi, Naoyuki Yamamoto. Release of an anti-anxiety peptide in casein hydrolysate with Aspergillus oryzae protease. Food & function. 2022. 13. 20. 10449-10460
Yu Hirata, Kazuhiro Nomura, Daisuke Kato, Yoshihisa Tachibana, Takahiro Niikura, Kana Uchiyama, Tetsuya Hosooka, Tomoaki Fukui, Keisuke Oe, Ryosuke Kuroda, et al. A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy. The Journal of clinical investigation. 2022. 132. 10. 1-13
Peng Gao, Takahiro Adachi, Shinsaku Okai, Naoki Morita, Daisuke Kitamura, Reiko Shinkura. Integrin CD11b provides a new marker of pre-germinal center IgA+ B cells in murine Peyer's patches. International immunology. 2022. 34. 5. 249-262
Kunihiko Kotake, Toshihiko Kumazawa, Kiminori Nakamura, Yu Shimizu, Tokiyoshi Ayabe, Takahiro Adachi. Ingestion of miso regulates immunological robustness in mice. PLOS ONE. 2022. 17. 1. e0261680-e0261680

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MISC (212)：

永石宇司, 井上忠彦, 伏見萌音, 山田大貴, 岡本隆一, 安達貴弘. 腸管IgAの最先端~明らかになりつつあるIgAによる腸管微生物叢制御機構とその重要性~IgAによる回腸免疫恒常性の維持. 消化器病学サイエンス. 2023. 7. 2
中島綾香, 安田光佑, 鈴木健吾, 安達貴弘. Immunomodulatory functions of Euglena gracilis and its component paramylon. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
佐藤文孝, 城玲央奈, 森口幸太, グエンコン・タン, エフマドイジャーズ, 尾村誠一, 朴雅美, 安達貴弘, 角田郁生. IgA抗体欠損は実験的自己免疫性脳脊髄炎を軽減させる. Neuroimmunology. 2023. 28. 1
安達貴弘. IgAと回腸炎. 臨床免疫・アレルギー科. 2022. 78. 2. 206-211
平田悠, 野村和弘, 加藤大輔, 橘吉寿, 新倉隆宏, 内山奏, 細岡哲也, 福井友章, 大江啓介, 黒田良祐, et al. KLF15を介した筋萎縮の分子機構の解明. 糖尿病. 2022. 65. Suppl.1. S-122

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Patents (4)：

Books (5)：

生体イメージングによる食シグナルおよび未病・病態の解析
2020
B細胞内のカルシウム伝達機構第5回 B細胞カルシウムシグナル. 炎症と免疫. 24(1)
2016
フローサイトメトリー自由自在
細胞工学 2004
Allergenic proteins in rice. Postharvest biochemistry of plant food materials in tropic 共著
Japan Scientific Society Press 1994
蛋白質生産菌Bacillus brevis47細胞壁蛋白質遺伝子の発現調節
[出版者不明] 1990

Lectures and oral presentations (34)：

生体イメージングによる免疫応答および腸管センシングの可視化解析
(JAFI 2022 2022)
腸管バリア機能を中心としたPrecision Healthのための食の体系的な評価 ~腸管バリア機能を高める食品とその機序~
(JAFI 2022 2022)
Precision Healthのための食の体系的な免疫評価システムの構築
(日本食品免疫学会第17回学術大会 2021)
IgA deficiency causes spontaneous enteritis
(The 48th Annual Meeting of The Japanese Society for Immunology 2019)
Elucidation of recognition mechanism of dorsal root ganglion for food factors
(The international conference on food factors(ICoFF2019) 2019)

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Works (2)：

B細胞抗原受容体シグナル伝達機構
1997 -
Signaling of B cell antiger receptor
1997 -

Education (3)：

- 1990 Nagoya University Graduate School, Division of Agriculture
- 1985 Nagoya University School of Agricultural Sciences
- 1985 Nagoya University Faculty of Agriculture

Professional career (1)：

Ph.D (Nagoya University)

Work history (10)：

2021/04/01 - 現在 Tokyo Medical and Dental University Medical Research Institute Associate Professor
2014/04/01 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Life Science and Technology Life Science and Technology Immunology Associate Professor
2007/04 - 現在 Tokyo Medical and Dental University Medical Research Institute
1993/04/01 - 2021/03/31 Tokyo Medical and Dental University Medical Research Institute Pathophysiology Immunology Associate Professor
2012/04/01 - 2016/02/29 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Immunology Associate Professor

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Committee career (2)：

2014 - 現在日本免疫学会 “免疫ふしぎ未来”実行委員
2014 - 2015 日本学術振興会特別研究員等審査会専門委員および国際事業委員会書面審査員

Awards (4)：

2022/11 - Japanese Association for Food Immunology Award of Japanese Association for Food Immunology
2021/10 - Japanese Association for Food Immunology Poster Award
2013/10 - 日本食品免疫学会ポスター賞
1998 - 研究奨励賞持田記念医学薬学振興財団

Association Membership(s) (5)：

THE JAPANESE BIOCHEMICAL SOCIETY , THE JAPANESE SOCIETY FOR IMMUNOLOGY , 日本分子生物学会 , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , The Japanese society for Food immunology

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