Research field (2):
Experimental pathology
, Human pathology
Research keywords (3):
動脈硬化
, 実験病理学
, Experimental Pathology
Research theme for competitive and other funds (55):
2017 - 2020 Development of Forecasting Technology for Onset of Aortic Dissection using X-ray Phase-contrast Tomography and Vascular Ultrasonography
2014 - 2017 Studies on pathogenesis of failure of vascular integrity and fate in pathological vascular remodeling.
2014 - 2017 Expression and functional analyses of R-spondin-Lgr6 signaling pathway in lung cancer
2010 - 2012 Detection of the molecular target in intractable non-small cell lung cancer
2010 - 2012 Pathological studies on molecular basis of failure of vascular homeostasis and pathological vascular remodeling.
2007 - 2008 「脱リン酸化」の視点から見る腫瘍細胞機能修飾の分子病理に関する萌芽的研究
2007 - 2008 Elucidation of mechanism of the modification of intratumoral microenvironment in antitumor effect of intratumoral activated dendritic cell therapy
2007 - 2008 Moleculo-Pathological studies on intracellular cross-talk signal in angiogenic and lymphoangiogenic process
2007 - 2008 Moleculo-pathological Study on Vascular Remodeling in Japanese
2006 - 2007 Pathophysiological Mechanisms of Angiogenesis-Related Diseases
2005 - 2007 Newly Gene Therapy Targetting Inhibition of the Multi-drug Resistance Using Decoy System
2005 - 2006 新規受容体型PTPによる細胞機能変換の分子機構に関する萌芽的研究
2005 - 2006 血管内皮細胞におけるCaspr3の病理学的・生物学的特性に関する萌芽的研究
2005 - 2006 Isolation and identification of tissue stem cell for clinical application
2004 - 2006 Newly Gene Therapy Targeting Inhibition of the Tumor Angiogenesis Using Decoy System
2004 - 2006 Moleculo-pathological Study on the Homeostatic and Deregulated Mechanisms of Vascular Remodeling
2004 - 2005 Study in genetic factors in retinopathy of prematurity
2004 - 2005 Basic Research for Complex Molecular Mechanisms of the Process of the Functional Angiogenesis : toward the development of technologies controlling the molecular target of pathological angiogenesis.
2003 - 2005 おとり遺伝子を用いた血管新生抑制による新規の癌遺伝子治療法の開発と応用
2003 - 2004 病理標本におけるタンパク質発現動態からの分子病態解析の試み
2002 - 2004 新規遺伝子導入ベクターを用いた慢性関節リウマチの治療法の開発
2002 - 2004 Moleculo-Pathological studies on intracellular cross-talk signal in angiogenic process.
2002 - 2003 Newly Gene Therapy Targetting Inhibition of the Tumor Angiogenesis Using Decoy System
2002 - 2003 Hierarchical Regulation of Multiple Angiogenic Growth Factors During 'Functional' Angiogenesis In Vivo
2001 - 2003 Molecular Pathophysiological Study on Endothelial Function Occurring during Vascular Remodeling
2001 - 2002 PEDFによる血管新生阻害機構の分子病理学的解析と治療への応用
2001 - 2002 ESTABLISHMENT AND APPLIANCE OF NEWLY GENE THERAPY FOR DEGENERATIVE ARTHRITIS OF THE TEMPOROMANDIBULAR JOINT
2000 - 2002 Deveelopment of Novel Gene Theray Strategies Using Recombinant Sendai Virus.
2000 - 2001 Role of human cytomegalovirus infection and the expression of immediate early gene products (CMV-IE) in the pathogenesis of vascular lesion formations
1999 - 2001 Patho-physiological studies on cellular interaction in vascular injury and vascular remodeling
2000 - 2000 動脈硬化発生・進展における血管内皮細胞機能に関する分子病理学的研究
1999 - 2000 ディファレンシャルディスプレイを利用した病理標本の分子病態学的研究
1999 - 2000 Trial research for practical use of the reagent for gene expression control by Decoy oligo nucleotide.
1999 - 2000 Regulation of Vascular Remodeling by Gene Transfer and Its Clinical Application : Exploration of Novel Gene Transfer Vector and Gene Therapy for Atherosclerosis, Angiogenic Diseases and Organ Infarction
1999 - 2000 ESTABLISHMENT AND APPLIANCE OF NEWLY GENE THERAPY FOR DEGENERATIVE ARTHROSIS USING DECOY STRATEGY
1998 - 2000 Molecular pathobiological Study on Endothelial Function Ocurring during Vascular Remodeling
1999 - 1999 動脈硬化発生・進展における血管内皮細胞機構に関する分子病理学的研究
1998 - 1999 腫瘍増殖におけるメタロエンドペプチダーゼEP-24.16の分子病態学的解析
1998 - 1998 動脈硬化発生・進展における血管内皮細胞機能に関する分子病理学的研究
1997 - 1998 Molecular pathological studies on physiological function of VEGF in atherosclerotic Vessels
1997 - 1997 動脈硬化発生・進展における血管内皮細胞機能に関する分子病理学的研究
1996 - 1996 遺伝子導入ベクターの開発とin vivo応用
1996 - 1996 Endothelial Modulation of Vascular Remodeling
1995 - 1996 Molecular pathological studies on physiological function of VEGF in atherosclerotic Vessels
1995 - 1996 in situ immunocytochemical study of adhesion molecules expressed on endothelium in atherosclerosis-prone mouse
1994 - 1995 Molecular Pathology of Endothelial Function in the Regulation of Vascular Response to Injuries
1994 - 1994 肝ミクロゾームメタルプロテアーゼの特異的インヒビターの精製と構造解析
1993 - 1993 ビタミンK依存性凝固因子のプロセシングプロテアーゼの構造と機能解析
1992 - 1993 Molecular Pathological Study on Endothelial Regulation of Blood-Vascular Wall Interaction
1991 - 1993 Molecular Mechanism of Extrinsic Blood Coagulation Pathway
1991 - 1991 血管内血管新生における内皮細胞・平滑筋細胞相互反応に関する分子病理学的研究
肺腫瘍細胞の増殖制御に関する研究
血管新生に関する研究
Study on angiogenesis
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Papers (77):
Kazunori Nakagawa, Mitsuru Tanaka, Tae Hun Hahm, Huu-Nghi Nguyen, Toshiro Matsui, Yong-Xiang Chen, Yutaka Nakashima. Accumulation of Plasma-Derived Lipids in the Lipid Core and Necrotic Core of Human Atheroma: Imaging Mass Spectrometry and Histopathological Analyses. Arteriosclerosis, Thrombosis, and Vascular Biology. 2021
Koki Yokawa, Masato Hoshino, Naoto Yagi, Yutaka Nakashima, Kazunori Nakagawa, Yutaka Okita, Kenji Okada, Takuro Tsukube. Synchrotron Radiation-based X-ray phase-contrast imaging of the aortic walls in acute aortic dissection. JVS: Vascular Science. 2020. 1. 81-91