Nagata Koh-ichi

ナガタコウイチ | Nagata Koh-ichi

Affiliation and department：
Other affiliations (1)：

Homepage URL (1)： http://kaken.nii.ac.jp/ja/r/50252143

Research field (6)： Functional biochemistry , Medical biochemistry , Fetal medicine/Pediatrics , Pathobiochemistry , Cell biology , Neurosurgery

Research keywords (8)：分子細胞生物学 , 知的障害 , 小児てんかん , 自閉性障害 , 大脳皮質発生 , 細胞骨格 , シグナル伝達 , 神経細胞

Research theme for competitive and other funds (40)：

2022 - 2025 Pathophysiological mechanisms of epilepsies caused by KCNQ2 gene abnormalities
2019 - 2022 Pathophysiological mechanisms of neurodevelopmental disorders caused by abnormalities of cell cycle-regulatory genes
2021 - 2022 子宮内胎仔脳遺伝子導入法を用いた結節性硬化症モデルマウスの作出と評価
2020 - 2022 POGZ遺伝子異常を原因とする発達障害の病態メカニズム解析
2020 - 2022 遺伝子異常を原因とする発達障害におけるアストロサイトの病態意義の解明

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Papers (171)：

Masashi Nishikawa, Shin Hayashi, Atsushi Nakayama, Yosuke Nishio, Anna Shiraki, Hidenori Ito, Kouichi Maruyama, Yukako Muramatsu, Tomoo Ogi, Seiji Mizuno, et al. Pathophysiological significance of the p.E31G variant in RAC1 responsible for a neurodevelopmental disorder with microcephaly. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2024. 167520-167520
Tomoki Ishiguro, Mariko Noda, Masashi Nishikawa, Koh-ichi Nagata, Hidenori Ito. Variations associated with neurodevelopmental disorders affect ARF1 function and cortical development. The Journal of Biochemistry. 2024
Masashi Nishikawa, Koh-ichi Nagata, Hidenori Tabata. Live Imaging of Migrating Neurons and Glial Progenitors Visualized by in Utero Electroporation. Methods in Molecular Biology. 2024. 201-209
Nanako Hamada, Takuma Nishijo, Ikuko Iwamoto, Sagiv Shifman, Koh-ichi Nagata. Analyses of Conditional Knockout Mice for Pogz, a Gene Responsible for Neurodevelopmental Disorders in Excitatory and Inhibitory Neurons in the Brain. Cells. 2024. 13. 6. 540-540
Hidenori Tabata, Koh-ichi Nagata, Kazunori Nakajima. Time-lapse imaging of migrating neurons and glial progenitors in embryonic mouse brain slices. J. Vis. Exp. 2024. 205. e66631. 1-12

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MISC (43)：

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Lectures and oral presentations (16)：

Insights into the cell biology of autism through the identification and characterization of causal genes
(Symposium: Genes, Metabolites and Neural Circuits: Studying Causative Genetic Mutations to Reveal Mechanistic Pathways for Gut-Brain Nervous Development and Autism Spectrum Disorder, The 15th Meeting of the Asian-Pacific Society for Neurochemistry 2018)
Comprehensive analyses of causative genes for ASD with in utero electropolation technique
(International Symposium on Autism 2017 2017)
Comprehensive analyses of RBFOX1, a causative gene for neurodevelopmental and psychiatric diseases, in the brain development
(Symposium: Common molecular aspects of neurodevelopmental and psychiatric disorders. The 14th Meeting of the Asian-Pacific Society for Neurochemistry 2016)
Comprehensive approach to understand pathophysiological role of SIL1, a gene causing intellectual disability
(Symposium; Harnessing Human Genetics to Define the Biochemical Pathways involved in Brain Development: 25th Meeting of International Society for Neurochemistry 2015)
Comprehensive approach with an analytical battery to understand pathophysiological role of A2BP1/RBFOX1, a "hub" gene in the ASD gene transcriptome network
(Keystone Symposia on Molecular and Cellular Biology Pathways of Neurodevelopmental Disorders 2015)

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Education (2)：

Professional career (1)：

Work history (6)：

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Committee career (4)：

Awards (3)：

Association Membership(s) (7)：

米国神経化学会 , The Japanese Society Of Child Neurology , 米国細胞生物学会 , 国際神経化学会 , 日本神経化学会 , 日本臨床分子形態学会 , 日本生化学会

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