Research theme for competitive and other funds (15):
2022 - 2027 64Cu-ATSM局所治療:切除困難な膠芽腫への革新的術中RI治療への挑戦
2022 - 2025 放射性標識抗体を用いた膵がん超早期画像診断法の臨床試験に向けた製剤化研究
2022 - 2025 難治性胆管がんの代謝を利用した新規放射性治療薬開発
2019 - 2022 Development of imaging method for early pancreatic cancer by high-resolution PET using radiolabeled antibody
2016 - 2019 Personalized radiosensitized radioimmunotherapy for peritoneal dissemination
2013 - 2016 Development of a screening system to select the personalized anti-cancer drugs and diagnostic probes for PET monitoring
2012 - 2015 Basic research program for targeted radionuclide cancer therapy using alpha-particle radiation
2011 - 2012 Prediction of Targeted Therapy Outcome for Fatty Acid Synthase by Acetate PET
2009 - 2010 Study on internal-radiotherapy with ^<64>Cu-ATSM targeting cancer stem cell-rich regions in tumors.
2007 - 2008 Study on molecular imaging for tumor-specific acetate metabolism
2005 - 2006 演示実験に基づいた物理教育方法の開発
がん 放射線 生物学
がん細胞の低酸素代謝 腫瘍分子イメージング 放射線治療
Cancer Radiology Biology
Hypoxic metabolism of tumor cells
Show all
Papers (60):
Mitsuhiro Shinada, Masashi Takahashi, Chika Igarashi, Hiroki Matsumoto, Fukiko Hihara, Tomoko Tachibana, Masakazu Oikawa, Hisashi Suzuki, Ming-Rong Zhang, Tatsuya Higashi, et al. 64Cu2+ Complexes of Tripodal Amine Ligands' In Vivo Tumor and Liver Uptakes and Intracellular Cu Distribution in the Extrahepatic Bile Duct Carcinoma Cell Line TFK-1: A Basic Comparative Study. Pharmaceuticals (Basel, Switzerland). 2024. 17. 7
Mitsuhiro Shinada, Hisashi Suzuki, Masayuki Hanyu, Chika Igarashi, Hiroki Matsumoto, Masashi Takahashi, Fukiko Hihara, Tomoko Tachibana, Chizuru Sogawa, Ming-Rong Zhang, et al. Trace Metal Impurities Effects on the Formation of [64Cu]Cu-diacetyl-bis(N4-methylthiosemicarbazone) ([64Cu]Cu-ATSM). Pharmaceuticals (Basel, Switzerland). 2023. 17. 1. 10
Tomoko Tachibana, Tomoko Gowa Oyama, Yukie Yoshii, Fukiko Hihara, Chika Igarashi, Mitsuhiro Shinada, Hiroki Matsumoto, Tatsuya Higashi, Toshihiko Kishimoto, Mitsumasa Taguchi. An In Vivo Dual-Observation Method to Monitor Tumor Mass and Tumor-Surface Blood Vessels for Developing Anti-Angiogenesis Agents against Submillimeter Tumors. International Journal of Molecular Sciences. 2023. 24. 24. 17234-17234
Yukie Yoshii, Hiroki Matsumoto, Chika Igarashi, Tomoko Tachibana, Fukiko Hihara, Mitsuhiro Shinada, Atsuo Waki, Sei Yoshida, Kenichiro Naito, Kimiteru Ito, et al. Process to Remove the Size Variants Contained in the Antibody-Chelator Complex PCTA-NCAB001 for Radiolabeling with Copper-64. Pharmaceuticals (Basel, Switzerland). 2023. 16. 10. 1341
吉井幸恵, 檜原扶紀子, 松本博樹, 五十嵐千佳, 立花知子, 品田光洋, 張明栄, 大島聡人, 佐藤秀光, 成田善孝, et al. Evaluation of hypoxia-targeting radiopharmaceutical 64Cu-ATSM for PET monitoring with local therapy in high-grade glioma model. 日本脳腫瘍学会学術集会プログラム・抄録集. 2022. 40th
Diversity of carotenoids in the Prasinophyceae, primitive members of green plants.
Photosynthesis: Fundamental Aspects to Global Perspectives.Allen Press, Lawrence. 2005
Diversity of carotenoids in the Prasinophyceae, primitive members of green plants.
Photosynthesis: Fundamental Aspects to Global Perspectives.Allen Press, Lawrence. 2005
Lectures and oral presentations (100):
放射性金属錯体を用いた診断一体型治療薬開発
(日本薬学会第 144 年 会 2024)
Innovative visible cancer treatment using radiopharmaceuticals
(The 8th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science 2024)
64Cu-ATSM internal radiotherapy to treat colon cancer acquiring resistance to antiangiogenic therapy with bevacizumab
(The Society of Nuclear Medicine (SNM) annual meeting 2016 2016)
Cu-ATSMを用いた低酸素イメージングとその応用
(第75回日本医学放射線学会総会 2016)
Evaluation of simultaneous dual-isotope SPECT/PET/CT imaging with 99mTc and 64Cu by phantom study and its in vivo application
(2015 Pacifichem (The meeting of International Chemical Congress of Pacific Basin Societies) 2015)