Ohga Shouichi

オオガショウイチ | Ohga Shouichi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.med.kyushu-u.ac.jp/pediatr/

Research field (3)： Fetal medicine/Pediatrics , Hematology and oncology , Immunology

Research keywords (8)：免疫不全症 , 臨床免疫学 , 小児血液腫瘍学 , 小児血液免疫学 , Immunodeficiency , Clinical Immunology , Pediatric Hematology/Oncology(immunohematology) , Pediatric Hematology/Immunology

Research theme for competitive and other funds (30)：

2024 - 2025 小児期に発症する心筋炎の病因と心筋障害機構の解析
2022 - 2025 Study on the etiology and its molecular pathogenesis of pediatric-onset myocarditis
2018 - 2021 高機能データベースを用いた先天性心疾患患者のための包括的看護支援システムの構築
2017 - 2020 Neonatal and pediatric research on liver regenerative medicine using umbilical cord blood
2016 - 2020 Elucidation of the etiology and development of the novel therapy using stem cells from human exfoliated deciduous teeth for Hirschsprung's disease and its allied disorders

2015 - 2018 The investigation of pathophysiology and biomarkers in subacute sclerosing panencephalitis (SSPE)

2015 - 2017 Bronchial asthma induces excessive inflammation and virus replication in pandemic influenza infection.

2013 - 2016 Development of new therapies for intractable diseases in pediatric surgery using stem cells from human exfoliated deciduous teeth

2013 - 2016 Analysis of the factor of low immune responses to pneumococcal conjugate vaccine and Hemophilus influenzae type b conjugate vaccine in immunocompromised children

2012 - 2015 Study on the comprehensive treatment strategy of hemophagocytic syndrome

2011 - 2012 Liver regeneration using stem cells from hteeth (SHED) for congenital metabol

2009 - 2011 Research on the pathogenesis and treatment of Epstein-Barr virusassociated intractable diseases

2007 - 2008 Therapeutic strategy and biological characterization of Epstein-Barr virus (EBV) infected cells in chronic active EBV infection

2003 - 2004 Analysis of pathogenesis and pathophysiology of congenital bone marrow failure for the establishment of the treatment strategy

2002 - 2003 Analysis of the pathogenesis and identification of candidate genes in familial hemophagocytic lymphohistiocytosis

2001 - 2002 Analysis on the activated T-cells in lymphoproliferative diseases

1999 - 2000 T-cell analysis on chronic active Epstein-Barr virus (EBV) infection and EBV-associated lymphoproliferative diseases

1998 - 1999 Molecular and immmunological analyses of cytokines and γδT cells in intracellular infection of Salmonella

1996 - 1996 組織球増殖性疾患の病態解析と骨髄移植を含めた治療プロトコールに関する研究

1995 - 1995 化膿性髄膜炎の免疫学的解析:デキサメサゾン療法の有用性と炎症サイトカインの検討

1994 - 1994 悪性細網症とその類縁疾患における炎症性サイトカインの解析

1993 - 1993 炎症性サイトカインの生体防御機構における役割とその臨床的意義

1992 - 1992 炎症性サイトカインの感染防御機構における意義

EBウイルス関連疾患に関する研究

免疫不全症・免疫異常症の臨床的研究

造血不全症の診断と治療に関する研究

Study on Epstein-Barr virus associated lymphoproliferative disease

Study on Bone Marrow Failure Syndrome

Study on Clinical Roles of Inflammatory Cytokines

Study on Diagnosis and Treatment of Congenital Immunodeficiency

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Papers (614)：

Kentaro Nakashima, Takashi Imai, Akira Shiraishi, Ryoko Unose, Hironori Goto, Yusaku Nagatomo, Kanako Kojima-Ishii, Yuichi Mushimoto, Kei Nishiyama, Kenichiro Yamamura, et al. The immunoreactive signature of monocyte-derived dendritic cells from patients with Down syndrome. Clinical and experimental immunology. 2024. 217. 3. 291-299
Ryoji Taira, Satoshi Akamine, Sayaka Okuzono, Fumihiko Fujii, Eriko Hatai, Kousuke Yonemoto, Ryuichi Takemoto, Hiroki Kato, Keiji Masuda, Takahiro A. Kato, et al. Gnao1 is a molecular switch that regulates the Rho signaling pathway in differentiating neurons. Scientific Reports. 2024. 14. 1
Sayaka Okuzono, Fumihiko Fujii, Daiki Setoyama, Ryoji Taira, Yohei Shinmyo, Hiroki Kato, Keiji Masuda, Kousuke Yonemoto, Satoshi Akamine, Yuki Matsushita, et al. An N-terminal and ankyrin repeat domain interactome of Shank3 identifies the protein complex with the splicing regulator Nono in mice. Genes to Cells. 2024
Fumihiko Fujii, Hikaru Kanemasa, Sayaka Okuzono, Daiki Setoyama, Ryoji Taira, Kousuke Yonemoto, Yoshitomo Motomura, Hiroki Kato, Keiji Masuda, Takahiro A Kato, et al. ATP1A3 regulates protein synthesis for mitochondrial stability under heat stress. Disease models & mechanisms. 2024
畑井恵理子, チョン・ピンフィー, 安倍時子, 梶原健太, 藤井史彦, 園田有里, 栂尾理, 酒井康成, 才津浩智, 井上健, et al. 後天性眼振を示したHypomyelination of Early Myelinating Structureの2歳男児. 脳と発達. 2024. 56. Suppl. S191-S191

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MISC (344)：

田中惇史, 福岡将治, 豊村大亮, 長友雄作, 平田雄一郎, 本村良知, 永田弾, 賀来典之, 山村健一郎, 大賀正一. 冠攣縮性狭心症で発症したCOVID-19ワクチン後心筋炎の1例. 日本小児科学会雑誌. 2022. 126. 7. 1090-1090
岩屋友香, 西山慶, 本村良知, 岡部安博, 大賀正一. 小児移植腎尿路感染症に対する抗菌薬投与方法についての検討. 日本臨床腎移植学会プログラム・抄録集. 2022. 55回. 230-230
澤田貴彰, 城戸淳, 菅原敬信, 吉田真一郎, 石井加奈子, 井上貴仁, 遠藤文夫, 大賀正一, 廣瀬伸一, 中村公俊. 熊本県と福岡県におけるポンペ病の新生児スクリーニング. 日本マス・スクリーニング学会誌. 2021. 31. 2. 226-226
Yasunari Sakai, Sayaka Okuzono, Christian P. Schaaf, Shouichi Ohga. Translational pediatrics: clinical perspective for Phelan-McDermid syndrome and autism research. Pediatric Research. 2021
Shunsuke Yamamoto, Masataka Ishimura, Keisuke Taku, Yutaro Yada, Katsuhide Eguchi, Wakato Matsuoka, Akira Shiraishi, Hirosuke Inoue, Masayuki Ochiai, Shouichi Ohga. Postnatal Cytomegalovirus Infection-Associated Hemolytic Anemia in an Infant Born to a Lupus Mother. PEDIATRIC BLOOD & CANCER. 2020. 67

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Books (2)：

ab型T細胞レセプター欠損による複合免疫不全症
臨床免疫 2003
血液・リンパ節疾患再生不良性貧血
今日の治療指針第13版医学書院 2002

Education (2)：

- 1984 Yamaguchi University School of Medicine Faculty of Medicine
- 1984 Yamaguchi University Faculty of Medicine

Professional career (1)：

MD, PhD (Kyushu University)

Committee career (5)：

- 現在日本産婦人科・新生児血液学会評議員
- 現在日本小児血液がん学会評議員
- 現在日本血液学会代議員
- 現在日本小児科学会代議員
- 現在日本小児感染症学会評議員

Association Membership(s) (7)：

日本産婦人科・新生児血液学会 , 日本造血細胞移植学会 , 日本臨床免疫学会 , 日本小児感染症学会 , 日本小児血液がん学会 , 日本血液学会 , 日本小児科学会

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