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J-GLOBAL ID：200901026411925584 Update date: Mar. 24, 2025

Otsuki Takemi

オオツキタケミ | Otsuki Takemi

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Affiliation and department：
Job title：所長
Homepage URL (1)： https://ug-to.com/

Research field (3)： Hygiene and public health (non-laboratory) , Hygiene and public health (laboratory) , Healthcare management, medical sociology

Research keywords (11)： Health Promotion Housing , Tumor Immunity , Autoimmuine , Immune Tolerance , Environmental Substances , Asbestos , Silicates , Silica , myeloma , Human Myeloma Cell Line , Carcinogenesis

Research theme for competitive and other funds (35)：

2020 - 2023 Development of irregular X-chromosome inactivation-specific targeted therapy
2020 - 2022 環境物質誘発性自己免疫疾患発症のトリガーイベントの探索
2019 - 2022 トランスクリプトーム解析に基づく悪性中皮腫診断に寄与する免疫バイオマーカーの探索
2018 - 2021 Exploratory research for toxic machinery of titanate nanosheet leading to immunological influences
2017 - 2020 Immune cell polarization in autoimmune diseases caused by environmental particles

2016 - 2020 Analysis for mechanism involved in the suppressed immune response of CTL under exposure to asbestos

2016 - 2019 Comprehensive immunological-analyses for patients with malignant mesothelioma and diffuse pleural thickening

2015 - 2018 Immunotoxicity of titanate nanosheets

2015 - 2018 Effect of short-term and long-term exposure of asbestos on regulatory T cells

2013 - 2018 Classification and alternative methods for sensitizers

2013 - 2016 Analysis for the effect of silica particle exposure on immune system

2012 - 2015 Comprehensive analysis for immunological characteristics of tumor and autoimmune diseases related with mineral particles and fibers

2012 - 2015 Analysis of suppression of Th2-type immune responses through innate immunity by glyco-polymer bearing plant antigenic N-glycans

2010 - 2013 Protection against Asbestosis.

2009 - 2011 Construction of the experimental system about the immunity influence of an indoor disposition

2006 - 2011 環境免疫学

2006 - 2011 Environmental Immunology

2008 - 2010 Anaylisis of immunological alterations affecting asbestos-induced carcinogenesis

2007 - 2008 環境中物質の免疫影響スクリーニングシステム構築

2006 - 2007 ANALYSIS OF IMMUNOLOGICAL TARGET MOLECULES FOR MOLECULAR PREVENTION OF ASBESTOS-RELATED TUMOR FORMATIONIN CASES WHO EXPOSED ASBESTOS

2004 - 2005 Phenotypic and functional alteration of regulatory T cells in the peripheral blood of patients with silicosis

2004 - 2005 FALURE OF SELF TOLERANCE INDUCED BY ENVIRONMELAL SUBSTANCES : AUTOIMMUNE DYSREGULATION FOUND IN SILICOSIS PATIENIS AS A MODEL

2002 - 2003 EXPERIMENTAL STUDY ON ACTION MECHANISMS OF RESISTANCE TO HORMONAL THERAPY AND OVERCOMING THIS RESISTANCE IN BREAST CANCER

2002 - 2003 The elucidation of the radiation resistance in melanoma : the relationship between melanogenesis and Elkind recovery

2002 - 2003 EXTRACTION OF FACTORS RELATED TO THE ONCOGENESIS, PROGRESSION AND SENSITIVITY TO THE THERAPEUTIC AGENTS IN HUMAN MYELOMA CELLS AS IN VITRO MODEL

2001 - 2002 プロテインチップを用いた珪肺症患者における免疫学的病態の解析

2000 - 2001 Experimental Study on Overcoming Resistance to Hormonal Therapy in Breast Cancer

2000 - 2001 Risk factors analysis using HLA typing for preventive medicine of worker's immunological sensitivities against silica dust.

1999 - 2000 Analysis of HLA disease association among the patients patients with silicosis-To make a check list to prevent work-related diseases.

1997 - 1998 Research for immunodysregulation and acquisition of autoimmunity induced by silica compounds

1997 - 1998 Occupational exposure of toxic materials and development of autoimmune diseases

1991 - 1991 ヒト骨髄腫細胞株を用いた多発性骨髄腫における癌遺伝子の研究

1991 - 1991 わが国に特有な赤血球膜異常症,特に膜蛋白分画4,2の病態に関する遺伝生化学的研究

1990 - 1990 ヒト骨髄腫細胞株を用いた多発性骨髄腫の悪性化機構に関するc-myc発現の研究

1989 - 1989 二相液体培養法による遺伝性赤血球膜疾患赤芽球細胞膜の発生分化に関する生化学的研究

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Papers (425)：

Hirohiko Sueki, Kazuteru Noguchi, Bunki Natsumoto, Keishi Fujio, Yutaro Hayashi, Yuko Kaneko, Takahisa Gono, Kuninobu Wakabayashi, Haruka Ito, Takahiko Yoshimoto, et al. Predictive and diagnostic biomarkers for cytomegalovirus infection in patients with rheumatic musculoskeletal diseases treated by high-dose glucocorticoid therapy: multicentre, prospective cohort study. Clinical and experimental rheumatology. 2025
A trial of food pattern analysis and leftover food evaluation of side dishes in a school lunch central kitchens in Okayama Prefecture. 2023. 7. 1. 72-80
EunSeon Lee, Suni Lee, Yasuya Tashiro, Mari Ogihara, Hideaki Watanabe, Satoshi Ishibashi, Shigeki Nagata, Kana Miyo, Makoto Ohara, Takemi Otsuki, et al. Sequential screening of biomarkers in a case of drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms occurring with virus reactivation and autoimmune disease. The Journal of dermatology. 2022. 49. 7. e221-e223
西村泰光, 李順姫, 武井直子, 伊藤達男, 上月稔幸, 藤本伸一, 大槻剛巳. 主成分分析による悪性中皮腫のニボルマブ治療効果に関わる免疫動態の評価⇔. 日本衛生学雑誌. 2022. 77. Suppl. S204-S204
Suni Lee, Shoko Yamamoto, Yurika Shimizu, Bandaru Srinivas, Nagisa Sada, Naoko Kumagai-Takei, Tatsuo Ito, Yasumitsu Nishimura, Masayasu Kusaka, Kozo Urakami, et al. Construction of bioscore for detection of self-tolerance failure: From analysis of silicosis cases. Translational Autoimmunity. 2022. 347-356

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MISC (98)：

西村泰光, 李順姫, 武井直子, 松崎秀紀, 藤本伸一, 岸本卓巳, 大槻剛巳. 遺伝子発現量解析に基づく新規NK細胞機能指標の確立、悪性中皮腫患者における特徴. 日本衛生学雑誌. 2023. 78. Suppl. S187-S187
山内明, 山内明, 山内明, 西村泰光, 西村泰光, 西村泰光, 向井知之, 向井知之, 向井知之, 松本啓志, et al. Activity Report of Industry-Academia Collaboration and Intellectual Property Management Section, Kawasaki Medical School-the middle of 2020 fiscal year to the middle of 2021-. 川崎医学会誌一般教養篇. 2022. 47
武井直子, 西村泰光, 李順姫, 吉留敬, 伊藤達男, 大槻剛巳. ケモカインレセプターに注目した長期石綿曝露CD8+T細胞亜株の機能解析. 日本衛生学雑誌. 2021. 76. Suppl. S171-S171
李順姫, 山本祥子, 伊藤達男, 武井直子, 西村泰光, 大槻剛巳. 石綿長期曝露ヒト制御性T細胞モデル株におけるMMP-7発現亢進と抗腫瘍免疫減弱との関連. 日本衛生学雑誌. 2021. 76. Suppl. S172-S172
野口和照, 壷井和幸, 李順姫, 山本祥子, 青山裕美, 大槻剛巳, 松井聖. non-HIV IRIS症例におけるサイトカイン測定の意義についての検討. 日本臨床免疫学会総会プログラム・抄録集. 2020. 48回. 121-121

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Patents (4)：

Books (45)：

Environmental health
IntechOpen 2021 ISBN:9781839687204
Allergy and immunotoxicology in occupational health-the next step
Springer Nature Singapore 2020 ISBN:9789811547348
Allergy and Immunotoxicology in Occupational Health - The Next Step; (Series Title: Current Topics in Environmental Health and Preventive Medicine) (Otsuki T; Di Gioacchino M; Petrarca C. eds)
Springer 2020
Allergy and Immunotoxicology in Occupational Health - The Next Step; (Series Title: Current Topics in Environmental Health and Preventive Medicine) (Otsuki T; Di Gioacchino M; Petrarca C. eds)
Springer 2020
Asbestos-related Diseases / (Ed) Otsuki T
IntechOpen 2020

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Works (19)：

二〇二三年夏 - 八月の蜃気楼「岡山の文学」令和5年度岡山県文学選奨現代詩部門準佳作
大槻剛巳 2024 - 現在
二〇二三年夏 - 七月の泡に消える「岡山の文学」令和5年度岡山県文学選奨現代詩部門準佳作
2024 - 現在
二〇二三年夏 - 六月のバースデイ「岡山の文学」令和5年度岡山県文学選奨現代詩部門準佳作
大槻剛巳 2024 - 現在
Rainy Days ~ Dear Nancy
2021 - 現在
Rainy Days ~ Dear Nancy
Takemi Otsuki 2021 - 現在

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Education (3)：

1985 - 1989 Kawasaki Medical School Department of Medical Research
1986 - 1986 Hematology/Oncology, the Institute of Medical Science, the University of Tokyo
1975 - 1981 Kawasaki Medical School School of Medicine Department of Medicine

Professional career (1)：

(BLANK) (Kawasaki Medical School)

Work history (11)：

2021/04 - 現在新庄村国民健康保険内科診療所
2021/04 - 現在 Kawasaki Medical School
2003/04 - 2021/03 Kawasaki Medical School
1997/04 - 2003/03 Kawasaki Medical School
1996/04 - 1997/03 Kawasaki Medical School

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Committee career (63)：

2021/04 - 現在日本血液学会功労会員
1997/04 - 現在日本内科学会中国地方評議員
1991/04 - 現在日本血液学会専門医
1989/11 - 現在日本内科学会総合内科専門医
1985/12 - 現在日本内科学会認定内科医

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※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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