Research theme for competitive and other funds (21):
2020 - 2023 Identification of VWF-HBD in vascular growth and interaction with an inhibitory VEGF isoform
2017 - 2020 Therapeutic application of BOECs in von Willebrand disease
2016 - 2019 Novel mutation search of antithrombin resistance and its pathological analysis research by mouse model
2015 - 2018 ヒトiPSおよび新規遺伝子改変マウスを用いたネフローゼ症候群の病因解明
2013 - 2016 Animal models and hemostatic pathophysiology of acquired von Willebrand syndrome (AvWS)
2013 - 2016 Molecular elucidation of antithrombin resistance mechanism and development of thrombophilia model mouse.
2012 - 2015 RhoF promotes murine marginal zone B cell development
2010 - 2012 Separation of VWF domain function using gene-targeted mic
2010 - 2012 Gene analysis of a novel thrombotic risk factor; antithrombin-resistance.
2007 - 2008 Elucidation of Molecular basis of inherited and acquired protein S deficiency as a thrombosis risk factor
2007 - モノクローナル抗体によるTMA治療モデルの確立
2005 - 2006 Molecular mechanisms of thrombosis in mouse model induced by age and stress
2004 - 2005 Analysis on thrombotic tendency in obesity and diabetes by use of model mouse
2004 - 2005 Fatal thrombosis of antithrombin deficient mice is rescued differently in the heart and liver by intercrossing with low tissue factor mice
2004 - 2005 Elucidation of molecular basis of May-Hegglin anomaly and its related disordes
2003 - 2004 Molecular mechanisms of thrombosis in mouse model induced by age and stress
2002 - 2003 The physiological role of the interaction of VWF-GPIb : Amino acid residues of the platelet GPIb to bind VWF and the generation of knock-in mice mutated at Lys599 to A1a.
2001 - 2002 Antithrombin deficiency in mice results in embryonic lethality and thrombotic tendency.
2000 - 2001 Identification of the regulatory elements of human von Willebrand factor for binding to platelet GPlb.
2000 - 2001 Identification of the amino acid residues of the platelet GPIbα essential for the von Willebrand factor binding by the clustered charged-to-alanine scanning mutagenesis
Fumie Nakashima, Takahiro Shibata, Kohei Kamiya, Jun Yoshitake, Ryosuke Kikuchi, Tadashi Matsushita, Isao Ishii, Juan A. Giménez-Bastida, Claus Schneider, Koji Uchida. Structural and functional insights into S-thiolation of human serum albumins. Scientific Reports. 2018. 8. 1. 932
Hattori Hikaru, Ishikawa Yuichi, Kawashima Naomi, Akashi Akimi, Yamaguchi Yohei, Harada Yasuhiko, Hirano Daiki, Adachi Yoshiya, Miyao Kotaro, Ushijima Yoko, et al. Identification of the novel deletion-type PML-RARA mutation associated with the retinoic acid resistance in acute promyelocytic leukemia. PLOS ONE. 2018. 13. 10. e0204850
- 1992 Nagoya University Graduate School, Division of Medicine First Department of Internal Medicine
Professional career (1):
Doctor of Medicine (Nagoya University)
Work history (4):
2010/03/01 - 現在 Nagoya University Nagoya University Hospital Department of Blood Transfusion Service Professor
2005/04/01 - 2010/02/28 Nagoya University Hospital
2005/02/01 - 2010/02/28 Nagoya University Nagoya University Hospital Hematology Lecturer
1999/04/01 - 2005/03/31 Nagoya University Hospital
Committee career (3):
2010/04/01 - 現在 N/A
2010/04/01 - 現在 情報連携統括本部会議 委員
2010/04/01 - 現在 男女共同参画専門委員会 委員
Awards (1):
1994/11 - 日本血栓止血学会 日本血栓止血学会 第1回学術奨励賞
Association Membership(s) (9):
American Society for Biochemistry and Molecular Biology
, 日本臨床検査自動化学会
, International Society in Thrombosis and Hemostasis
, American Association of Blood Banks
, American Society of Hematolohy
, 日本検査血液学会
, 日本臨床検査医学会
, 日本血栓止血学会
, 日本輸血・細胞治療学会