Rchr
J-GLOBAL ID：200901027840386655   Update date: Sep. 13, 2024

Yuan Bo

エン パク | Yuan Bo
Affiliation and department：
Josai University Faculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences

About Josai University Faculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences


Research field  (3)： Tumor biology ,  Clinical pharmacy ,  Pharmaceuticals - health and biochemistry
Research keywords  (9)： 薬物トランスポーター ,  抗がん剤 ,  がん ,  天然物由来物質 ,  薬物併用効果 ,  医療系薬学 ,  生物系薬学 ,  Cell Biology ,  Biopharmaceutics
Research theme for competitive and other funds  (13)：
  • 2024 - 2027 認知機能障害に対する新規クルクミン誘導体の予防・改善効果に関する基礎研究
  • 2024 - 2027 抗ネクロトーシス作用を持ち合わせた安全性が高い抗酸化化合物の探索と脳保作用の検討
  • 2024 - 2027 RXRを分子標的としたジヒドロピリミジン誘導体の抗悪性腫瘍薬への基礎的研究
  • 2024 - 2027 Fundamental research of antitumor activity of darinaparsin, a novel organic arsenical, against leukemic cells
  • 2021 - 2024 Fundamental research of antidepressant-like effect of a novel curcumin derivative CUD003 in mice
Show all
Papers (81)：
  • Takashi Asano, Meiyan Xuan, Naohiro Iwata, Jun Takayama, Kousuke Hayashi, Yosuke Kato, Toshiya Aoyama, Hiroshi Sugo, Hirokazu Matsuzaki, Bo Yuan, et al. Involvement of the Restoration of Cerebral Blood Flow and Maintenance of eNOS Expression in the Prophylactic Protective Effect of the Novel Ferulic Acid Derivative FAD012 against Ischemia/Reperfusion Injuries in Rats. International Journal of Molecular Sciences. 2023. 24. 11. 9663-9663
  • Bo Yuan, Hidetomo Kikuchi, Jingmei Li, Atsushi Kawabata, Kozo Yao, Norio Takagi, Mari Okazaki. Cytotoxic Effects of Darinaparsin, a Novel Organic Arsenical, against Human Leukemia Cells. International Journal of Molecular Sciences. 2023. 24. 3. 2282-2282
  • Bo Yuan, Jingmei Li, Shin-Ich Miyashita, Hidetomo Kikuchi, Meiyan Xuan, Hirokazu Matsuzaki, Naohiro Iwata, Shinya Kamiuchi, Katsuyoshi Sunaga, Takeshi Sakamoto, et al. Enhanced Cytotoxic Effects of Arenite in Combination with Active Bufadienolide Compounds against Human Glioblastoma Cell Line U-87. Molecules. 2022. 27. 19. 6577-6577
  • 渡口 由姫, 菊地 秀与, 西村 良夫, 袁 博, 新井 理絵, 久保 貴紀, 長 秀連, 須永 克佳. ヒト急性前骨髄球性白血病細胞株NB4に対する2-methylthio dihydropyrimidine誘導体の細胞毒性. 日本薬学会年会要旨集. 2022. 142年会. 26PO5-06S
  • Yoshio Nishimura, Hidetomo Kikuchi, Takanori Kubo, Rie Arai, Yuki Toguchi, Bo Yuan, Katsuyoshi Sunaga, Hidetsura Cho. Synthesis of 4,4-Disubstituted 3,4-Dihydropyrimidin-2(1H)-ones and -thiones, the Corresponding Products of Biginelli Reaction Using Ketone, and Their Antiproliferative Effect on HL-60 Cells. Chemical and Pharmaceutical Bulletin. 2022. 70. 2. 111-119
ｍore...
MISC (56)：
  • 渡口 由姫, 菊地 秀与, 西村 良夫, 袁 博, 新井 理絵, 久保 貴紀, 長 秀連, 須永 克佳. ヒト急性前骨髄球性白血病細胞株NB4に対する2-methylthio dihydropyrimidine誘導体の細胞毒性. 日本薬学会年会要旨集. 2022. 142年会. 26PO5-06S
  • 菊地 秀与, 渡口 由姫, 西村 良夫, 袁 博, 新井 理絵, 久保 貴紀, 長 秀連, 須永 克佳. ヒト白血病細胞株NB4およびHL-60に対する2-thioxo-dihydropyrimidine誘導体の細胞毒性. 日本薬学会年会要旨集. 2022. 142年会. 26PO5-07
  • 青山隼也, XUAN Meiyan, 野木麻理奈, 高山淳, 坂本武史, 松崎広和, YUAN Bo, 岡崎真理. Cytoprotective effect of a ferulic acid derivative FAD012 against oxidative stress injury in RBMVE cells. 日本薬学会年会要旨集(Web). 2022. 142nd
  • XUAN Meiyan, 小笠原晃輔, 鈴木涼介, 石黒直人, 小川健太, 高山淳, 坂本武史, 松崎広和, YUAN Bo, 岡崎真理. Cytoprotective effect of a ferulic acid derivative FAD041 against oxidative stress injury in Neuro-2a cells. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 高山淳, XUAN Meiyan, 小山貴大, 大塚夏希, 松崎広和, BO Yuan, 岡崎真理, 坂本武史. Anti-inflammatory activity and docking simulation with target protein of curcumin derivative CUD003. 日本薬学会年会要旨集(Web). 2022. 142nd
ｍore...
Lectures and oral presentations  (3)：
  • Basic research and history of clinical application of arsenic compounds
    (2023)
  • 微量元素研究領域の最前線:生理機能の解明と創薬研究 ヒ素化合物の臨床応用および抗腫瘍活性メカニズム
    (Biomedical Research on Trace Elements 2021)
  • 元素の力で切り拓く次世代の低分子創薬〜重水素から高周期元素まで ヒ素化合物の抗腫瘍活性およびその新規臨床応用の可能性(Anti-tumor activity of arsenic compounds and its potential novel application in clincs)
    (日本薬学会年会要旨集 2021)
Education (2)：
  • 1998 - 2000 Tokyo University of Pharmacy and Life Sciences Department of Pharmaceutical Sciences, Graduate School of Pharmacy Pharmacy
  • 1988 - 1993 ShenYang Pharmaceutical University School of Pharmacy Pharmacy
Professional career (1)：
  • Ph.D.
Work history (7)：
  • 2022/10 - 現在 Josai University Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences Department of Pharmaceutical Professor
  • 2019/04 - 2022/09 School of Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University Laboratory of Pharmacology Associate professor
  • 2013/04 - 2019/03 Tokyo University of Pharmacy and Life Sciences Department of Applied Biochemistry, School of Pharmacy Assistant professor
  • 2009/04 - 2013/03 Tokyo University of Pharmacy and Life Sciences Department of Clinical Molecular Genetics, School of Pharmacy Assistant professor
  • 2009/07 - 2010/08 University of California, San Francisco (UCSF) Department of Bioengineering and Therapeutic Sciences Visiting assistant professor
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Awards (3)：
  • 2012/03 - Tokyo University of Pharmacy and Life Sciences Nakako Yoshida Memorial Award Cytocidal effects of arsenite on human-derived normal and malignant cells, and its pharmacokinetics in APL patients
  • 1999 - Iwaki Scholarship Foundation Scholarship from Iwaki Scholarship Foundation
  • 1998 - Scholarship of Independent Administrative Institution Japan Student Services Organization Scholarships for International Students in Japan
Association Membership(s) (4)：
Specialty Committee of Hematology of World Federation of Chinese Medicine Societies Council Member & Vice Secretary General ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  The Japanese Pharmacological Society
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