Rchr
J-GLOBAL ID：200901029777143383   Update date: May. 01, 2024

Sugimura Haruhiko

スギムラ ハルヒコ | Sugimura Haruhiko
Affiliation and department：
Sasaki Foundation Sasaki Institute

About Sasaki Foundation Sasaki Institute


Job title： Director
Homepage URL  (1)： http://www.sasaki-institute.org
Research field  (2)： Experimental pathology ,  Human pathology
Research keywords  (16)： immune and metabolic check point ,  genome medicine ,  FISH ,  chromosomal instability ,  lung cancer ,  genetic polymorphism ,  adductome ,  DNA adduct ,  gastric cancer ,  実験腫瘍学 ,  分子疫学 ,  腫瘍病理学 ,  分子病理学 ,  Experimental Oncology ,  Molecular Epidemiology ,  Molecular Pathology
Research theme for competitive and other funds  (47)：
  • 2023 - 2027 Gene-environment interactions inducing spatial expansion of mutant clones in human normal tissues
  • 2022 - 2027 Understanding a mechanism of an onset of colorectal cancer by colibactin and finding compounds inhibiting colibactin biosynthetic enzymes
  • 2018 - 2021 LIX1L蛋白質発現癌細胞でのRNA翻訳伸長反応制御による標的治療薬開発研究
  • 2016 - 2018 RNA modifications of human tumors
  • 2014 - 2018 Involvement of Akt/mTOR in lung cancer and design of novel therapy targeting them
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Papers (262)：
  • Augustin Nzitakera, Jean Bosco Surwumwe, Ella Larissa Ndoricyimpaye, Schifra Uwamungu, Delphine Uwamariya, Felix Manirakiza, Marie Claire Ndayisaba, Gervais Ntakirutimana, Benoit Seminega, Vincent Dusabejambo, et al. The spectrum of TP53 mutations in Rwandan patients with gastric cancer. Genes and environment : the official journal of the Japanese Environmental Mutagen Society. 2024. 46. 1. 8-8
  • De Hu, Hidetaka Yamada, Katsuhiro Yoshimura, Tsutomu Ohta, Kazuo Tsuchiya, Yusuke Inoue, Kazuhito Funai, Takafumi Suda, Yuji Iwashita, Takuya Watanabe, et al. High Expression of Fas-Associated Factor 1 Indicates a Poor Prognosis in Non-Small-Cell Lung Cancer. Current oncology (Toronto, Ont.). 2023. 30. 11. 9484-9500
  • 金子 雅直, 中島 光子, 杉浦 喜一, 石田 夏樹, 田村 智, 谷 伸也, 山出 美穂子, 濱屋 寧, 大澤 恵, 立田 協太, et al. 大腸髄様癌はMLH1欠損かつBRAFV600E変異陽性の特徴を有する. 日本消化器病学会雑誌. 2023. 120. 臨増大会. A801-A801
  • Masanao Kaneko, Mitsuko Nakashima, Kiichi Sugiura, Natsuki Ishida, Satoshi Tamura, Shinya Tani, Mihoko Yamade, Yasushi Hamaya, Satoshi Osawa, Kyota Tatsuta, et al. Both MLH1 deficiency and BRAFV600E mutation are a unique characteristic of colorectal medullary carcinoma: An observational study. Medicine. 2023. 102. 38. e35022
  • Naotaka Izuo, Hajime Miyanishi, Daisuke Nishizawa, Takuma Fujii, Junko Hasegawa, Naomi Sato, Fumihiko Tanioka, Haruhiko Sugimura, Kazutaka Ikeda, Atsumi Nitta. DNA methylation status of SHATI/NAT8L promoter in the blood of cigarette smokers. Neuropsychopharmacology Reports. 2023
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MISC (792)：
  • 斎藤彩香, 五十嵐久喜, 北山康彦, 石川励, 山田英孝, 椙村春彦. Archives of formalin-fixed, paraffin-embedded (FFPE) tissues: Genetic analysis of 50-year-old FFPE tissue blocks. 医学検査. 2023. 72. 2
  • ンジタケーラ オギシテ, マニラキザ フェリックス, 石川励, 夏目宏子, 岩下雄二, 山田英孝, 椙村春彦, 新村和也. TP53 mutation spectrum of Rwandan gastric cancer differ from the one of Japan, China and Eastern Europe. 日本癌学会学術総会抄録集(Web). 2023. 82nd
  • 金子雅直, 中島光子, 杉浦喜一, 石田夏樹, 田村智, 谷伸也, 山出美穂子, 濱屋寧, 大澤恵, 立田協太, et al. 大腸髄様癌はMLH1欠損かつBRAFV600E変異陽性の特徴を有する. 日本消化器病学会雑誌(Web). 2023. 120
  • FELIX Manirakiza, 山田英孝, 岩下雄二, 石野佳子, TAO Hong, 椙村春彦. Novel TP53 frameshift mutations in Romanian colorectal cancers. 大腸癌研究会プログラム・抄録集. 2022. 96th
  • 奥田亜弥, 橋本志野, 田村和朗, 田村和朗, 小嶋志之, 山田英孝, 岩泉守哉, 椙村春彦. 遺伝性びまん性胃がん(Hereditary Diffuse Gastric Cancer:HDGC)の1例. 日本遺伝性腫瘍学会学術集会プログラム・抄録集. 2022. 28th
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Patents (13)：
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Books (3)：
  • ライフサイエンス 顕微鏡学ハンドブック
    朝倉書店 2017
  • Cancer and Inflammation Mechanisms
    Wiley 2014
  • Tumors of the central nervous system
    Springer Science+Business Media 2011
Lectures and oral presentations  (7)：
  • 質量分析によるDNA付加体の網羅的同定法の開発
    (2018 がん予防学術大会 2018)
  • Identification of gastric cancer-related DNA adducts by DNA adductome analysis
    (2017 EMGS Annual Meeting, Raleigh, NC 2017)
  • Individual susceptibility of gastric cancer, a perspective from molecular epidemiology
    (89th Annual Meeting of the Japanese Gastric Cancer Association 2017)
  • Updates of immunotherapyof lung cancer
    (International conference of update of cancer prevention and research, Lucknow, India 2017)
  • 日本の遺伝性胃がんの現状
    (日本癌学会 2016)
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Education (2)：
  • 1982 - 1986 The University of Tokyo
  • 1976 - 1982 The University of Tokyo Faculty of Medicine
Professional career (1)：
  • (BLANK)
Work history (9)：
  • 2023/06 - 現在 National University Corporation Hamamatsu University School of Medicine Professor Emeritus
  • 2022/05 - 現在 Sasaki Institute, Sasaki Foundation Director
  • 1995/11 - 2023/03 Hamamatsu University School of Medicine The First Department of Pathology (Department of Tumor Pathology) Professor
  • 2020/04 - 2022/03 Hamamatsu University School of Medicine
  • 1991/03 - 1995/11 Hamamatsu University School of Medicine The First Department of Pathology
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Committee career (10)：
  • 2019/04 - 現在 The Japanese Society of Hereditary Tumors Counciler
  • 2017/10 - 現在 日本家族性腫瘍学会 家族性腫瘍専門医
  • 2017/01 - 現在 日本胃癌学会 代議員
  • 2016/01 - 現在 日本胃癌学会 胃癌取り扱い規約 委員 15版
  • 2017 - 2019/06 日本がん疫学・分子疫学研究会 代表幹事
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Awards (1)：
  • 2015/04 - 日本病理学会 日本病理学賞 ヒトがんの個体感受性
Association Membership(s) (8)：
日本遺伝性腫瘍学会 ,  日本胃癌学会 ,  日本がん疫学・分子疫学研究会 ,  日本消化器病学会 ,  American Association for Cancer Research ,  日本癌学会 ,  日本肝臓学会 ,  日本病理学会
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