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J-GLOBAL ID:200901030070743706   Update date: Apr. 14, 2025

Imanishi Miki

イマニシ ミキ | Imanishi Miki
Affiliation and department:
Homepage URL  (1): http://www.scl.kyoto-u.ac.jp/~bfdc/index.html
Research field  (1): Pharmaceuticals - chemistry and drug development
Research keywords  (2): 生体機能化学 ,  biofunctional chemistry
Research theme for competitive and other funds  (19):
  • 2022 - 2025 Site-specific and high efficient epitranscriptomic manipulation based on the enzymatic activity
  • 2021 - 2024 Elucidation of the mechanism for dimensional response genome
  • 2021 - 2024 Biological function of non-canonical nucleic acids
  • 2021 - 2023 配列・環境依存的エピトランスクリプトーム制御法の開発と体内時計制御への展開
  • 2019 - 2022 Control of RNA modification aimed at antivirus activities
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Papers (83):
  • Tamaki Endoh, Yiwei Ling, Shujiro Okuda, Miki Imanishi. Identification of Endogenous Sequences Interacting with METTL3/METTL14 RNA Methyltransferase. ChemBioChem. 2025
  • Kenko Otonari, Yuri Asami, Kosuke Ogata, Yasushi Ishihama, Shiroh Futaki, Miki Imanishi. Highly sequence-specific, timing-controllable m6A demethylation by modulating RNA-binding affinity of m6A erasers. Chemical Communications. 2025
  • Kazuya Yamanaka, Yoshihisa Inoue, Miki Imanishi, Junko Ohkanda. Functional evaluation of an electrophilic focused library to identify a covalent inhibitor against intrinsically disordered circadian clock transcription factors. Bioorganic & medicinal chemistry letters. 2024. 98. 129588-129588
  • Kamui Tanaka, Akiyo Suda, Motonari Uesugi, Shiroh Futaki, Miki Imanishi. Xanthine derivatives inhibit FTO in an L-ascorbic acid-dependent manner. Chemical communications (Cambridge, England). 2023. 59. 72. 10809-10812
  • Shigeru Negi, Miki Imanishi, Mami Hamori, Yuka Kawahara-Nakagawa, Wataru Nomura, Kanae Kishi, Nobuhito Shibata, Yukio Sugiura. The past, present, and future of artificial zinc finger proteins: design strategies and chemical and biological applications. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2023. 28. 3. 249-261
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MISC (52):
more...
Lectures and oral presentations  (87):
  • Development of a simple detection method of RNA modification and its application
    (2024)
  • 配列・タイミング依存的なRNA修飾操作法の開発
    (日本薬学会第144年会 2024)
  • RNA脱メチル化酵素FTOの阻害剤探索及びFTOの補酵素としてのL-アスコルビン酸の役割
    (日本薬学会第144年会 2024)
  • RNAメチル化の人為的制御
    (第40回メディシナルケミストリーシンポジウム 2023)
  • 核酸構造の多元機能とエピトランスクリプトームとの 接点を知る
    (第13回CSJ化学フェスタ2023 2023)
more...
Education (5):
  • - 2002 Kyoto University
  • - 1999 Kyoto University
  • - 1999 Kyoto University Graduate School, Division of Pharmaceutical Sciences
  • - 1997 Kyoto University Faculty of Pharmaceutical Sciences
  • - 1997 Kyoto University Faculty of Pharmaceutical Science
Professional career (1):
  • Doctor of Pharmaceutical Science (Kyoto University)
Awards (4):
  • 2023/05 - 日本女性科学者の会 第28回日本女性科学者の会奨励賞 RNAメチル化の酵素化学的検出法の開発と選択的制御への展開
  • 2013/04 - 平成25年度文部科学大臣表彰若手科学者賞 細胞機能を制御する人工DNA結合タンパク質デザインの研究
  • 2012/03 - 日本薬学会 平成24年度日本薬学会奨励賞 人工DNA結合タンパク質のデザインと細胞機能制御への展開
  • 2011/12 - 京都大学化学研究所 第16回京大化研奨励賞 細胞時計のリセットを誘起する人工転写因子の創製
Association Membership(s) (4):
日本薬学会 ,  RNA Society ,  日本時間生物学会 ,  日本生化学会
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