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J-GLOBAL ID：200901033762535827 Update date: Apr. 18, 2025

OGRA Yasumitsu

オグラヤスミツ | OGRA Yasumitsu

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Affiliation and department：
Job title： Professor
Other affiliations (1)：

Chiba University

Homepage URL (1)： http://www.p.chiba-u.jp/lab/yobou/index.html

Research field (5)： Pharmaceuticals - health and biochemistry , Forensic medicine , Analytical chemistry , Environmental effects of chemicals , Pharmaceuticals - analytical and physicochemistry

Research keywords (2)：生体微量元素 biometals スペシエーション speciation 銅 copper セレン selenium ミネラル mineral 栄養補助食品 supplements ICP-MS ICP-MS キャピラリーHPLC capillary HPLC 質量分析 mass spectrometry , biometals speciation copper selenium mineral supplements ICP-MS capillary HPLC mass spectrometry

Research theme for competitive and other funds (30)：

2024 - 2027 Establishment of necrochemistry and its application to legal medicine, forensic toxicology and public health
2024 - 2027 Modification of detoxification of environmental toxicants by gut micro flora
2022 - 2024 Exploration of metabolomics associated with disaster-related death: Analysis of metabolome with hypothermia
2021 - 2024 Toxicological significance of metal biogenic nanoparticles
2019 - 2024 Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular System

2019 - 2024 Development of advanced speciation for the matabolism of biometals

2019 - 2022 Research on the development and application of metallomics methods in the field of environmental medicine

2018 - 2021 Molecular mechanisms underlying the formation of bioorganometallic bond for metal toxicology

2018 - 2020 Mechanism underlying the generation of reactive cyanogen species

2017 - 2020 Synthesis and biological evaluation of selenoneine, naturally occurring selenium containing compound

2016 - 2019 tissue distribution and toxic mechanism of indium nano particles

2016 - 2019 Speciation and toxicological study of antimony in the environmental water in eastern and mid-southern China

2015 - 2018 Elucidation of the metabolism and toxicity mechanism of arsenolipids by analytical chemistry techniques

2015 - 2017 Verification of the structure of selenophosphate

2014 - 2017 Metallome analysis with cellular differentiation

2012 - 2014 Development of novel on-site analysis of urinary selenometabolites

2011 - 2014 Organotin-induced GluR2 decrease and its in vivo neuronal effects

2011 - 2014 Elucidation of Selenium Metabolism in mammalian cells by speciation

2011 - 2014 Tissue indium distribution after intratracheal instillation

2011 - 2012 Chemical speciation of blood selenium in a population with high intake of mercury

2007 - 2009 Mechanisms underlying circulation of selenium in Biosphere

2004 - 2007 Metallomics of bio-trace elements : Copper, selenium and arsenic

2004 - 2006 生体微量元素のナノスペシエーションの開発とメタロミクスにおける応用

2002 - 2003 尿中の主セレン代謝産物セレノシュガーの生成機構と生物学的意義

2001 - 2002 重金属の細胞内移動に着目したメタロチオネインの核内移行の機構

2000 - 2001 Mechanisms Underlying the Metabolic Pathway of Selenium and the Interactions between Selenium and Other Elements

1998 - 1999 細胞内における銅および亜鉛の輸送機構の解明

1997 - 1999 Mechanism underlying the selective removal of copper accumulating in the liver of LEC rats and development of the therapy for Wilson disease

1996 - Biological and Toxicological Roles of Heavy Metals and Metalloids

1996 - 重金属および類金属の生物学的および毒性学的機能の解明

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Papers (224)：

Keita Muro, Arisa Yamasaki, Maki Matsumoto, Yu-Ki Tanaka, Yasumitsu Ogra, Toru Fujiwara, Akira Yoshinari, Junpei Takano. The polar-localized borate exporter BOR1 facilitates boron transport in tapetal cells to the developing pollen grains. Plant physiology. 2025
Makiko Iwase, Yu-Ki Tanaka, Yasunori Fukumoto, Noriyuki Suzuki, Yasumitsu Ogra. Laser Ablation Coupled with LC-ICP-MS for Local Speciation of Trace Elements in Tissues. Analytical chemistry. 2025. 97. 9. 5306-5312
Yasunori Fukumoto, Enhui Li, Yu-Ki Tanaka, Noriyuki Suzuki, Yasumitsu Ogra. Evaluation of Metal Accumulation in Escherichia coli Expressing SPL2 by Single-Cell Inductively Coupled Plasma Mass Spectrometry. International journal of molecular sciences. 2025. 26. 5
Yu-Ki Tanaka, Kemmu Matsuhashi, Yasumitsu Ogra. Analytical techniques for arsenic speciation. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2025
Yu-ki Tanaka, Hinano Katayama, Risako Iida, Yasumitsu Ogra. Quantitative elemental analysis of human leukemia K562 single cells by inductively coupled plasma mass spectrometry in combination with a microdroplet generator. Journal of Analytical Atomic Spectrometry. 2025

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MISC (64)：

福田彩乃, 山岸由和, 永澤明佳, 永澤明佳, 小椋康光, 小椋康光. Mechanism of cold stress response in human hepatocarcinoma cells (HepG2). 衛生薬学・環境トキシコロジー講演要旨集. 2024. 2024
山岸由和, 井上博之, 永澤明佳, 永澤明佳, 岩瀬博太郎, 小椋康光, 小椋康光. Post-mortem degradation of flunitrazepam in blood. 衛生薬学・環境トキシコロジー講演要旨集. 2024. 2024
片山愛美, 永澤明佳, 岩瀬博太郎, 小椋康光. Determination of Acylcarnitines as a Biomarker of Insulin Poisoning by LC-QTOF/MS. 衛生薬学・環境トキシコロジー講演要旨集. 2024. 2024
永澤明佳, 永澤明佳, 千葉文子, 千葉文子, 鳥光優, 鳥光優, 山岸由和, 猪口剛, 猪口剛, 槇野陽介, et al. Investigation of postmortem fatal concentration of escitalopram. 日本薬学会年会要旨集(Web). 2024. 144th
山岸由和, 永澤明佳, 永澤明佳, 岩瀬博太郎, 小椋康光, 小椋康光. Development of toxicological biomarkers originating from human serum albumin for organophosphorus pesticides. 日本薬学会年会要旨集(Web). 2024. 144th

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Patents (10)：

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Books (4)：

病の錬金術化学物質はなぜ毒になりうるのか (ニュートン新書)
ニュートンプレス 2024 ISBN:4315528447
衛生薬学(改訂第2版): 基礎・予防・臨床
南江堂 2018 ISBN:452440354X
Metallomics : recent analytical techniques and applications
Springer 2017 ISBN:9784431564614
衛生薬学: 基礎・予防・臨床
南江堂 2016 ISBN:4524403175

Works (1)：

Speciation of Selenium in Biological and Food Samples

Education (2)：

- 1996 Graduate School of Pharmaceutical Sciences, Chiba University
- 1991 Tokyo University of Pharmacy and Life Sciences School of Pharmacy

Professional career (1)：

Ph. D.(Pharmaceutical Sciences) (Chiba University)

Work history (7)：

2025/03 - 現在国立医薬品食品衛生研究所食品部客員研究員
2024/04 - 現在 Chiba University Graduate School of Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences Dean
2023/10 - 現在 Science Council of Japan Associate Member
2016/04 - 現在 Chiba Univesity Graduate School of Pharmaceutical Sciences Professor
2023/04 - 2024/03 Chiba University Graduate School of Medical and Pharmaceutical Sciences Dean

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Awards (10)：

2024/09 - 日本微量元素学会学会賞
2023/07 - The Japanese Society of Toxicology JSOT Award
2016/09 - 日本薬学会環境・衛生部会学術賞
2016/06 - 日本毒性学会日化協LRI賞
2014/03 - 日本薬学会学術振興賞

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Association Membership(s) (12)：

日本質量分析学会 , JAPANESE ASSOCIATION OF FORENSIC TOXICOLOGY , Japanese Society of Food Chemistry , Royal Society of Chemistry , THE JAPANESE SOCIETY OF TOXICOLOGY , LECラット研究会 , 日本微量元素学会 , 日本癌学会 , 日本生化学会 , 日本薬学会 , 日仏薬学会 , Society of Toxicology

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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