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J-GLOBAL ID:200901037294728499   Update date: Apr. 10, 2025

Sasaki Nobuya

ササキ ノブヤ | Sasaki Nobuya
Affiliation and department:
Job title: Professor
Other affiliations (1):
  • 35-1, Higashi-23, Towada, Aomori 034-0021 Japan
Research field  (10): Laboratory animal science ,  Veterinary medicine ,  Zoological sciences ,  Philosophy and ethics ,  Pathobiochemistry ,  Nephrology ,  Tumor biology ,  Metabolism and endocrinology ,  Genetics ,  Genomics
Research keywords  (12): Laboratory Animal Science ,  Laboratory Animal Medicine ,  Veterinary Ethics and Animal Welfare ,  The 3Rs ,  Alternative Methods for Experimental Animals ,  Anesthesia for laboratory animals ,  Nephrology ,  Medical Genetics ,  Genome Science ,  Animal Breeding and Genetics ,  Infectious Disease of Laboratory Animals ,  Animal Behavior
Research theme for competitive and other funds  (1):
  • https://nrid.nii.ac.jp/ja/nrid/1000020302614/
Papers (126):
  • Masaki Watanabe, Hayato R. Takimoto, Kazuki Hashimoto, Yuki Ishii, Nobuya Sasaki. Effectively simplified ADR-induced CKD mouse model: Retro-orbital vein injection vs. Tail-vein injection. Animal Models and Experimental Medicine. 2025. 8. 3. 568-572
  • Hayato Sasaki, Kazuki Otake, Kazuki Takeda, Eiki Takahashi, Jumpei Yasuda, Shizukaze Matsuda, Masaki Watanabe, Ayumu Kawasaki, Kosuke Otani, Muneyoshi Okada, et al. Protective function of the voltage-gated potassium channel Kv11.3 in a mouse model of cardiac ischemia/reperfusion injury. PLOS One. 2025
  • Koki Hiura & Masaki Watanabe (co-first author), Naoki Hirose, Kenta Nakano, Tadashi Okamura, Hayato Sasaki, Nobuya Sasaki. The mitotic spindle positioning (MISP) facilitates colorectal cancer progression by forming a complex with Opa interacting protein 5 (OIP5) and activating the JAK2-STAT3 signaling pathway. International Journal of Molecular Sciences. 2024. 25. 5. 3061
  • Masaki Watanabe, Kazuki Hashimoto, Yuki Ishii, Hayato R. Takimoto, Yuko Nikaido, Nobuya Sasaki. Assessment of thiamyral sodium as a euthanasia drug in mice. The Journal of Veterinary Medical Science. 2024. 86. 5. 480-484
  • Masaki Watanabe, Nobuya Sasaki. Mechanisms and future research perspectives on mitochondrial diseases associated with IARS gene mutations. Genes. 2024. 15. 7. 894
more...
MISC (3):
  • Masaki Watanabe, Nobuya Sasaki. What we learned through the development of a chronic kidney disease model mouse. OBELISK. 2025. 30. 1. 3-9
  • Hayato Sasaki, Nobuya Sasaki. Inducible mast cell-deficient mouse models. Clinical Immunology and Allergology. 2022. 77. 3. 389-396
  • Hiroshi Yamazeo, Nobuya Sasaki, Ichiro Miyoshi. The management of care and use of laboratory animals and its recent topics during COVID-19 crisis. Laboratory Animal and Environment. 2021. 58. 29. 81-92
Patents (5):
  • Prevention or treatment of tubulointerstitial disorders
  • Novel insulin-deficient mice
  • Proximal tubular epithelial cell lines and their use
  • Methods for sequencing
  • Test kit for infection by mouse hepatitis virus and Sendai virus using the polypeptide
Books (14):
  • Infectious Diseases of Animals, 5th ed.
    Kindai Shuppan Co., Ltd. 2025 ISBN:9784874023037
  • Animal Welfare Studies, enlarged edition
    2024 ISBN:9784812223215
  • Ethograms of Animals in Captivity
    Asakura Shoten 2024 ISBN:9784254450323
  • Laboratory Animal Anaesthesia and Analgesia (Paul Flecknell), 5th Edition
    2023 ISBN:9784910513164
  • AVMA Guidelines for the Euthanasia of Animals: 2020 Edition.
    ADTHREE 2022 ISBN:9784910513072
more...
Lectures and oral presentations  (292):
  • Development of a Model Mouse for Pediatric Mitochondrial Disease with IARS Abnormality: Its Association with Weak Calf Syndrome
    (The Molecular Biology Society of Japan 2024)
  • Development and characterization of a novel FVB-PrkdcR2140C mouse for adriamycin-induced nephropathy.
    (The 167th Annual Meeting of the Japanese Society of Veterinary Science, 2024)
  • Enhancement of LPS-induced apoptosis in the thymus of a mouse model of bovine IARS abnormality.
    (The 167th Annual Meeting of the Japanese Society of Veterinary Science 2024)
  • Mitotic Spindle Positioning (MISP) Facilitates Colorectal Cancer Progression by Forming a Complex with Opa Interacting Protein 5 (OIP5) and Activating the JAK2-STAT3 Signaling Pathway
    (The 167th Annual Meeting of the Japanese Society of Veterinary Science 2024)
  • Identification of a novel podocyte damage protective factor and analysis of its protective mechanism of action
    (The 167th Annual Meeting of the Japanese Society of Veterinary Science 2024)
more...
Education (2):
  • - 1997 Hokkaido University (Ph.D. of Medicine) Graduate School of Medicine
  • - 1992 Hokkaido University (Bachelor of Veterinary Medicine) School of Veterinary Medicine
Work history (8):
  • 2013 - 現在 School of Veterinary Medicine, Kitasato University Laboratory of Laboratory Animal Science and Medicine Professor
  • 2006 - 2013 Faculty of veterinary medicine, Hokkaido university Laboratory Animal Facility (AAALAC Accredited) Chief Veterinary
  • 2003 - 2013 Hokkaido University Laboratory of Laboratory Animal Science and Medicine Associate Professor
  • 2001 - 2003 University of California San Diego, Ludwig Cancer Research, Visiting Fellow
  • 1998 - 2001 The University of Tokyo Faculty of Pharmaceutical Sciences Assistant professor
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Committee career (27):
  • 2025 - 現在 獣医系大学間獣医学教育支援機構 vetCBT問題精選分科会委員
  • 2025 - 現在 Japanese Society for Alternatives to Animal Experiments Delegate
  • 2023 - 現在 The Japanese Society of Veterinary Science Executive director
  • 2023 - 現在 The Japanese Association for Laboratory Animal Medicine Chairman of the Board of Education
  • 2022 - 現在 The Japanese Association for Laboratory Animal Science Executive Director
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Awards (12):
  • 2025 - 日本実験動物学会 Experimental Animals 優秀論文賞
  • 2024 - The Japanese Society of Veterinary Science JALAM Maejima Award The mitotic spindle positioning (MISP) facilitates colorectal cancer progression by forming a complex with Opa interacting protein 5 (OIP5) and activating the JAK2-STAT3 signaling pathway.
  • 2024 - Japanese Association for Laboratory Animal Science Incentive Award Development of ADR nephropathy model and podocyte disorder model mice using TRECK method.
  • 2023 - The Japanese Society of Veterinary Science JALAM Maejima Award Pathophysiological analysis of IARS abnormality model mice
  • 2020 - Japanese Association for Laboratory Animal Medicine JALAS Maejima Award Analysis of novel nephropathy exacerbating factors in renal proximal tubular epithelial cells.
Show all
Association Membership(s) (10):
The Japanese Society of Nephrology ,  The Japanese Association of Laboratory Animal Medicine ,  The Japanese Society of Veterinary Science ,  The Japanese Society for Laboratory Animal Science ,  The Japanese Cancer Society ,  The Japanese College of Laboratory Animal Medicine ,  The Japanese Society for Animal Behaviour and Management ,  The Japanese Society for Alternatives to Animal Experiments. ,  The Japanese Association of Veterinary Nephrology and Urology ,  International Society of Nephrology
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