Sasaki Nobuya

• 35-1, Higashi-23, Towada, Aomori 034-0021 Japan

• https://nrid.nii.ac.jp/ja/nrid/1000020302614/

• Koki Hiura & Masaki Watanabe (co-first author), Naoki Hirose, Kenta Nakano, Tadashi Okamura, Hayato Sasaki, Nobuya Sasaki. The mitotic spindle positioning (MISP) facilitates colorectal cancer progression by forming a complex with Opa interacting protein 5 (OIP5) and activating the JAK2-STAT3 signaling pathway. International Journal of Molecular Sciences. 2024. 25. 5. 3061
• Masaki Watanabe, Kazuki Hashimoto, Yuki Ishii, Hayato R. Takimoto, Yuko Nikaido, Nobuya Sasaki. Assessment of thiamyral sodium as a euthanasia drug in mice. The Journal of Veterinary Medical Science. 2024. 86. 5. 480-484
• Masaki Watanabe, Nobuya Sasaki. Mechanisms and future research perspectives on mitochondrial diseases associated with IARS gene mutations. Genes. 2024. 15. 7. 894
• Shuji Shimada, Kyosuke Tanimoto, Hayato Sasaki, Takumi Taga, Takeru Sasaki, Tomomi Imagawa, Nobuya Sasaki. Automated scoring of glomerular injury in TNS2-deficient nephropathy. Experimental Animals doi: 10.1538/expanim.24-0001. 2024
• Kenta Onuma, Masaki Watanabe, Nobuya Sasaki. The grimace scale: a useful tool for assessing pain in laboratory animals. Experimental Animals. 2024. 73. 3. 234-245

ｍore...

• Hayato Sasaki, Nobuya Sasaki. Inducible mast cell-deficient mouse models. Clinical Immunology and Allergology. 2022. 77. 3. 389-396
• Hiroshi Yamazeo, Nobuya Sasaki, Ichiro Miyoshi. The management of care and use of laboratory animals and its recent topics during COVID-19 crisis. Laboratory Animal and Environment. 2021. 58. 29. 81-92

• Prevention or treatment of tubulointerstitial disorders
• Novel insulin-deficient mice
• Proximal tubular epithelial cell lines and their use
• Methods for sequencing
• Test kit for infection by mouse hepatitis virus and Sendai virus using the polypeptide

• Animal Welfare Studies, enlarged edition
  2024 ISBN:9784812223215
• Ethograms of Animals in Captivity
  Asakura Shoten 2024 ISBN:9784254450323
• Laboratory Animal Anaesthesia and Analgesia (Paul Flecknell), 5th Edition
  2023 ISBN:9784910513164
• AVMA Guidelines for the Euthanasia of Animals: 2020 Edition.
  ADTHREE 2022 ISBN:9784910513072
• Animal Welfare
  Syouwado 2022 ISBN:9784812221082

ｍore...

• Development of a Model Mouse for Pediatric Mitochondrial Disease with IARS Abnormality: Its Association with Weak Calf Syndrome
  (The Molecular Biology Society of Japan 2024)
• Development and characterization of a novel FVB-PrkdcR2140C mouse for adriamycin-induced nephropathy.
  (The 167th Annual Meeting of the Japanese Society of Veterinary Science, 2024)
• Enhancement of LPS-induced apoptosis in the thymus of a mouse model of bovine IARS abnormality.
  (The 167th Annual Meeting of the Japanese Society of Veterinary Science 2024)
• Mitotic Spindle Positioning (MISP) Facilitates Colorectal Cancer Progression by Forming a Complex with Opa Interacting Protein 5 (OIP5) and Activating the JAK2-STAT3 Signaling Pathway
  (The 167th Annual Meeting of the Japanese Society of Veterinary Science 2024)
• Identification of a novel podocyte damage protective factor and analysis of its protective mechanism of action
  (The 167th Annual Meeting of the Japanese Society of Veterinary Science 2024)

ｍore...

• - 1997 Hokkaido University (Ph.D. of Medicine) Graduate School of Medicine
• - 1992 Hokkaido University (Bachelor of Veterinary Medicine) School of Veterinary Medicine

• 2013 - 現在 School of Veterinary Medicine, Kitasato University Laboratory of Laboratory Animal Science and Medicine Professor
• 2006 - 2013 Faculty of veterinary medicine, Hokkaido university Laboratory Animal Facility (AAALAC Accredited) Chief Veterinary
• 2003 - 2013 Hokkaido University Laboratory of Laboratory Animal Science and Medicine Associate Professor
• 2001 - 2003 University of California San Diego, Ludwig Cancer Research, Visiting Fellow
• 1998 - 2001 The University of Tokyo Faculty of Pharmaceutical Sciences Assistant professor
1997 - 1998 JST Basic Research program, Postdoctoral Researcher
1995 - 1997 JSPS Research Fellowship for Young Scientists
1993 - 1994 Institute of Physical and Chemical Research, Research associate

• 2023 - 現在 The Japanese Society of Veterinary Science Executive director
• 2023 - 現在 The Japanese Association for Laboratory Animal Medicine Chairman of the Board of Education
• 2022 - 現在 The Japanese Association for Laboratory Animal Science Executive Director
• 2022 - 現在 The Japanese Association for Laboratory Animal Science Chair of the committee for the examination of articles of incorporation, rules and regulations, and legal provisions
• 2021 - 現在 The Japanese Association of Establishments for Veterinary Education Committee for the Improvement of Veterinary Education
2021 - 現在 The Japan University Accreditation Association Veterinary Education Evaluation Committee
2021 - 現在 The Japanese Society of Veterinary Science Chairman of the Pathological Veterinary Specialty Group
2020 - 現在 The Japanese College of Laboratory Animal Medicine Accreditation Committee
2020 - 現在 The Japanese Association for Laboratory Animal Medicine President
2015 - 現在 Tohoku Society for Laboratory Animals Auditor
2011 - 現在 Japanese Association for Laboratory Animal Medicine Executive Director
2008 - 現在 The Japanese Association for Laboratory Animal Science Board of Education
2005 - 現在 The Japanese Society of Veterinary Science Councilor
2005 - 現在 Japanese Society for Laboratory Animal Science Councilor
2021 - 2023 The Japanese Society of Veterinary Science Executive Directorctor
2019 - 2021 The Japanese College of Laboratory Animal Medicine Chairman of the Certification Examination Review Committee
2019 - 2021 The Japanese College of Laboratory Animal Medicine Academic committee
2019 - 2021 Japanese Society of Laboratory Animal Medicine Executive Director
2017 - 2021 The Japanese Association of Establishments for Veterinary Education Committee for the Study of Alternative Animal Methods
2017 - 2019 The Japanese Association for Laboratory Animal Medicine Chairman of the Maeshima Award Selection Committe
2017 - 2019 Japanese Society for Laboratory Animal Medicine Chairman of the Academic Assembly Committee
2016 - 2018 Ministry of Agriculture, Forestry and Fisheries Expert Member of the Veterinary Medical Council
2013 - 2015 The Japanese Association of Laboratory Animal Medicine Experimental Animal Regulations Review Committee
2010 - 2015 Japanese Association for Laboratory Animal Medicine Board of Medical Specialties Examiners
2015 - The Tohoku Society for Animal Experimentation Organizer
2010 - 2013 The Japanese Society for Laboratory Animal Science International Exchange Committee

• 2024 - The Japanese Society of Veterinary Science JALAM Maejima Award The mitotic spindle positioning (MISP) facilitates colorectal cancer progression by forming a complex with Opa interacting protein 5 (OIP5) and activating the JAK2-STAT3 signaling pathway.
• 2024 - Japanese Association for Laboratory Animal Science Incentive Award Development of ADR nephropathy model and podocyte disorder model mice using TRECK method.
• 2023 - The Japanese Society of Veterinary Science JALAM Maejima Award Pathophysiological analysis of IARS abnormality model mice
• 2020 - Japanese Association for Laboratory Animal Medicine JALAS Maejima Award Analysis of novel nephropathy exacerbating factors in renal proximal tubular epithelial cells.
• 2019 - Japan Society of Experimental Diabetes and Obesity Incentive award Congenic analysis of disease genes in a novel insulin-deficient diabetes model (ihs) mouse
2016 - The Japanese Society of Veterinary Science, JVMS Award 2016 : Functional validation of tensin2 SH2-PTB domain by CRISPR/Cas9-mediated genome editing.
2015 - Japanese Association for Laboratory Animal Science JALAS Maejima Award Search for tubulointerstitial injury resistance genes carried by C57BL/6J mice
2014 - Hokkaido Association for Laboratory Animal Research Hokkaido Association for Laboratory Animal Research Young Scientist Award A candidate gene for nephropathy resistance on chromosome 2 suppresses fibrosis of the renal interstitium.
2012 - The Japanese Society of Veterinary Science Japanese Veterinary Medical Association Conference Director's Award Development of an animal model of Hirschsprung's disease with a mutation in the endothelin receptor type B gene.
2012 - Japanese Association for Laboratory Animal Science. JALAS Maejima Award Development of an animal model of Hirschsprung's disease with a mutation in the endothelin receptor type B gene.
2010 - Japanese Association for Laboratory Animal Science. JALAS Maejima Award Genetic background of C57BL/6J mice is resistant to renal glomerulosclerosis

The Japanese Society of Nephrology ,  The Japanese Association of Laboratory Animal Medicine ,  The Japanese Society of Veterinary Science ,  The Japanese Society for Laboratory Animal Science ,  The Japanese Cancer Society ,  The Japanese College of Laboratory Animal Medicine ,  The Japanese Society for Animal Behaviour and Management ,  The Japanese Society for Alternatives to Animal Experiments. ,  The Japanese Association of Veterinary Nephrology and Urology ,  International Society of Nephrology