Research field (4)：
Food sciences
, Pharmaceuticals - chemistry and drug development
, Pharmacology
, Pharmaceuticals - health and biochemistry
Research keywords (6)：
薬物デザイン
, 生物薬剤学
, 薬物送達システム
, Drug Design
, Biopharmaceutics
, Drug Delivery System
Research theme for competitive and other funds (42)：
2023 - 2025 Development of covalent protein drug with unnatural amino acids
2016 - 2019 Preclinical and clinical study of influenza microneedle vaccine and analysis of immunity induction mechanism
2015 - 2017 Development of novel transdermal immunotherapy aimed at curing food allergies
2013 - 2016 Analysis of physicochemical characteristics of microneedle patch, and development of novel therapeutic approach for seborrheic keratosis treatment
2013 - 2015 Exploration of adjuvant for optimization of transcutaneous vaccine
2011 - 2012 Development of a novel transcutaneous vaccination device using a dissolving microneedle array.
2010 - 2012 Development of a tumor diagnosis system using novel immuno-PET/MRI probe
2008 - 2010 Construction of antibody-based molecular imaging techniques to analyze a development of tumor angiogenesis.
2005 - 2007 免疫担当細胞の体内動態制御に基づく癌治療の最適化
2005 - 2006 アポトーシス抵抗性を有する樹状細胞を用いた癌免疫療法の最適化
2004 - 2004 改変型アデノウイルスベクターを用いたin vivo胎盤毒性評価系の構築
2003 - 2004 Development of nanomedicine system based the control of intracellular pharmacokinetics.
2003 - 2004 高分子バイオコンジュゲート化アデノウイルスベクターの粒子設計とその評価
2001 - 2003 Development of intracellular controlled release system for optimization of gene therapy
2001 - 2003 Development of novel vaccine adjuvant for infectious disease
2001 - 2002 Development of Fiber-Mutant Adenovirus Vectors for targeting gene therapy
2001 - 2002 Enhancement of the specific activities of PEGylated proteins by a simple procedure using a reversible amino-protective reagent
Kenji Ishimoto, Yuma Konishi, Shuichi Otani, Soya Maeda, Yukio Ago, Nobumasa Hino, Masayuki Suzuki, Shinsaku Nakagawa. Suppressive effect of black tea polyphenol theaflavins in a mouse model of ovalbumin-induced food allergy. Journal of natural medicines. 2023. 77. 3. 604-609
Kotaro Sakamoto, Wararat Kittikulsuth, Eijiro Miyako, Akumwami Steeve, Rika Ishimura, Shinsaku Nakagawa, Yukio Ago, Akira Nishiyama. The VIPR2-selective antagonist KS-133 changes macrophage polarization and exerts potent anti-tumor effects as a single agent and in combination with an anti-PD-1 antibody. PloS one. 2023. 18. 7. e0286651
吾郷由希夫, 山田めゐ, 宮岡辰典, CHEN Lu, 石本憲司, 樋野展正, 中川晋作, 坂元孝太郎, 浅野智志. Development of mid-size molecule inhibitors of VIPR2 for the treatment of psychiatric disorders. 日本薬学会年会要旨集(Web). 2023. 143rd
高田理彩, 尾上遥南, 鈴木喬介, 石本憲司, 石本憲司, 大竹和正, 坂本健作, 吉岡靖雄, 中川晋作, 中川晋作, et al. Development of a next-generation ACE2-Fc formulation for SARS-CoV-2 mutant strains. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
石田莉子, 喜多絢海, 原田和生, 土井啓生, 池山直輝, 西浦崇史, 石本憲司, 石本憲司, 藤尾慈, 中川晋作, et al. Molecular mechanism of Ca-influx dependent modulation of the TET1 methylcytosine dioxygenase activity. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
