
	Chemical structure search How to Search	Import MOLfile format is only available (V3000 format is not available) Exact match Substructure search Superstructure search Substructure or superstructure search Similarity search

Details
Related links
Search

Co-authoring Researcher

Co-inventing Researcher

Researcher similar to the Researcher

Article similar to the Researcher

Patent similar to the Researcher

Research Project similar to the Researcher

Article(J-GLOBAL estimation)

Patent(J-GLOBAL estimation)

Rchr

J-GLOBAL ID：200901040010457432 Update date: Feb. 09, 2025

Okumura Toshikatsu

オクムラトシカツ | Okumura Toshikatsu

Clips

Affiliation and department：

Research field (1)： Gastroenterology

Research keywords (3)：神経消化器病学 , Neurogastroenterology , 総合診療

Research theme for competitive and other funds (26)：

2024 - 2027 脳内histamine神経系による腸管バリア制御機序の解明とleaky gut関連疾患への治療応用
2023 - 2026 中枢神経系を介した敗血症死阻止メカニズムの解明 -Ghrelinの関与ー
2022 - 2026 腹部手術後イレウスと術後せん妄に対する新規治療法の探究
2019 - 2022 Central mechanism of visceral sensation with special reference to brain orexin and its clinical application for irritable bowel syndrome
2018 - 2022 Exploring novel therapies on the basis of pathophysiological commonality between irritable bowel syndrome and metabolic syndrome

2014 - 2019 Understanding the adaptive brain function in relation to the alteration of posture-locomotor synergies

2014 - 2018 Role of brain orexin in the pathogenesis of irritable bowel syndrome

2014 - 2018 Roles of LPS, cytokine and peripheral CRF receptors on gastrointestinal function

2013 - 2018 Mechanisms of postural control operated by the basal ganglia, brainstem and spinal cord

2011 - 2013 The role and the mechanisms of orexin in modulating gastrointestinal function

2011 - 2012 Relationship between sleep-awake cycle and gastrointestinal motility

2010 - 2012 Anti-tumor action by PPARgamma ligands in pancreatic cancer: analysis of angigenesis-related genes expression

2009 - 2010 糖・脂質代謝研究に有用なin vitro小腸モデルの構築と臓器間相互作用の解析

2008 - 2010 ストレスキナーゼp38MAPKを介した抗癌剤耐性機構の解析と癌治療への応用

2008 - 2009 肝脂肪過剰蓄積を中枢へ伝達する迷走神経求心路刺激調節機構の解明と治療への応用

2008 - 2009 中枢性迷走神経刺激による肝臓で発現する遺伝子発現変化の網羅的解析

2005 - 2009 Neuronal mechanisms of initiation and selection of adaptive locomotor behaviors

2007 - 2008 Integrative control of psychomotor function and autonomic nervous system function by the basal ganglia

2006 - 2007 p38 MAPK signaling pathway-induced cell death in cancer chemotherapy

2006 - 2007 Molecular mechanism of the PPARγ ligand-induced growth arrest in GI cancers

2005 - 2006 Orexinergic systems responsible for the mechanisms of involved in the initiation and selection of emotional motor behaviors.

2004 - 2005 Involvement of p38 MAPK signaling pathway in cancer therapy

2004 - 2005 Inhibition of cell growth and cell invasion by PPAR gamma in GI cancers

2002 - 2003 Aproteasome-p27 system is involved in growth inhibition by PPARγ ligands in GI cancers

1999 - 2001 INTRINSIC ANTIMICROBIAL POLYPEPTIDE IN INFLAMMATROY BOWEL DISEASE

1999 - 2001 Role of a novel neurppeptide, orexin,in the central regulation of gastric acid secretion

Show all

Papers (290)：

Takuya Funayama, Tsukasa Nozu, Masatomo Ishioh, Sho Igarashi, Hiroki Tanaka, Chihiro Sumi, Takeshi Saito, Yasumichi Toki, Mayumi Hatayama, Masayo Yamamoto, et al. Splenectomy prevents brain orexin, ghrelin, or oxytocin but not GLP-1-induced improvement of intestinal barrier function in rats. Neurogastroenterology and motility. 2025. 37. 2. e14949
Kazuya Koyama, Hidetaka Iwamoto, Kenji Takahashi, Tetsuhiro Okada, Hidemasa Kawabata, Yohei Kitano, Hiroki Tanabe, Mikihiro Fujiya, Toshikatsu Okumura, Yusuke Mizukami. Cognitive and ataxic adverse events following entrectinib treatment in NTRK1 fusion gene-positive intrahepatic cholangiocarcinoma: a case report. Clinical journal of gastroenterology. 2025. 18. 1. 183-187
Yuya Sugiyama, Hiroaki Konishi, Tatsuya Dokoshi, Hiroki Tanaka, Yu Kobayashi, Takahiro Sasaki, Koji Yamamoto, Aki Sakatani, Keitaro Takahashi, Katsuyoshi Ando, et al. hsa_circ_0015388 Reduces Macrophage Derived Reactive Oxygen Species in Crohn's Disease. Inflammatory bowel diseases. 2025
Tsukasa Nozu, Saori Miyagishi, Masatomo Ishioh, Kaoru Takakusaki, Toshikatsu Okumura. The neurotensin receptor 1 agonist PD149163 alleviates visceral hypersensitivity and colonic hyperpermeability in rat irritable bowel syndrome model. Neurogastroenterology and motility. 2024. 36. 12. e14925
Nobuhiro Ueno, Seisuke Saito, Masahiro Sato, Yuya Sugiyama, Yu Kobayashi, Yuki Murakami, Kohjiro Sugimura, Takahiro Sasaki, Aki Sakatani, Keitaro Takahashi, et al. The clinical efficacy and safety of granulocyte and monocyte adsorptive apheresis in patients with Crohn's disease: A multicenter retrospective pilot study. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. 2024. 28. 3. 442-452

ｍore...

Education (2)：

1984 - 1988 Asahikawa Medical University Medical Related Research
1978 - 1984 Asahikawa Medical University School of Medicine

Professional career (1)：

(BLANK) (Asahikawa Medical University)

Work history (6)：

2022/04 - 現在 Asahikawa Medical University Vice President
2016/02 - 2024/03 Asahikawa Medical University Department of Medicine Professor
2002/12 - 2016/02 Asahikawa Medical University Department of General Medicine Professor
2000/04 - 2002/12 旭川医科大学内科学講座講師
1997/04 - 2000/04 Asahikawa Medical University

Show all

Committee career (3)：

2024/10 - 現在日本消化会病学会 IBS診療ガイドライン委員会 (第三版)委員長
2018/04 - 日本消化器病学会 IBS診療ガイドライン委員会 (第二版) 副委員長
2012/04 - 日本消化器病学会 IBS診療ガイドライン委員会委員

Awards (5)：

2006/10 - Hokkaidou Hokkaidou Ishikaishou
1997 - 第29回病態代謝研究会奨励賞
1997 - 第5回小野医学研究久木田研究奨励賞
1991 - 第18回日本実験潰病学会賞
1988 - 第13回世界消化器病学会優秀演題賞

Association Membership(s) (6)：

日本神経消化器病学会 , 日本内科学会 , 日本糖尿病学会 , 日本潰瘍学会 , 米国消化器病学会 , 日本消化器病学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page


	Free word	※Add the following synonyms, you can increase the number of hits.




		～