Rchr
J-GLOBAL ID:200901040167613799   Update date: Sep. 25, 2024

Uchiumi Fumiaki

ウチウミ フミアキ | Uchiumi Fumiaki
Research field  (1): Pharmaceuticals - health and biochemistry
Research theme for competitive and other funds  (6):
  • 2012 - 2016 Biological significance of the duplicated GGAA-motifs in the human TATA-less gene promoters
  • 2000 - 2001 ウイルス遺伝子転写抑制エレメントに結合する因子のcDNAクローニング
  • 1994 - 1996 Molecular mechanisms and function of apoptosis Faculty of Pharmaceutical Science
  • 1995 - 1995 アポトーシスを司るエンドヌクレアーゼの構造と機能
  • 1993 - 種々のヒト体細胞遺伝子プロモーター領域の解析
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Papers (73):
  • Matsushita T, Onishi A, Matsuyama T, Masuda T, Ogino Y, Kageyama M, Takahashi M, Uchiumi F. Rapid and efficient generation of mature retinal organoids derived from human 4 pluripotent stem cells via optimized pharmacological modulation of Sonic hedgehog, 5 activin A, and retinoic acid signal transduction. PLoS One. 2024. 19. 8. e0308743
  • Takenaka Y, Tanaka R, Kitabatake K, Uchiumi F, Aoki S, Kuramochi K, Tsukimoto M. Structure-Activity Relationship Analysis of Fluoxetine for Suppression of Inflammatory Cytokine Production. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2024. 47. 5. 946-954
  • Arakawa J, Kondoh H, Matsushita T, Ogino Y, Asai M, Tanuma SI, Uchiumi F. Induction of the human CDC45 gene promoter activity by natural compound trans-resveratrol. Mol Med Rep. 2024. 29. 6. 92
  • Yutaka Takihara, Ryuji Otani, Takuro Ishii, Shunsuke Takaoka, Yuki Nakano, Kaori Inoue, Steven Larsen, Yoko Ogino, Masashi Asai, Sei-ichi Tanuma and Fumiaki Uchiumi. Characterization of the human IDH1 gene promoter. AIMS Molecular Science. 2023. 10. 3. 186-204
  • Natsumi Ogawa, Shingo Nakajima, Kenya Tamada, Natsuki Yokoue, Haruki Tachibana, Miwa Okazawa, Takahiro Oyama, Hideaki Abe, Hiroaki Yamazaki, Atsushi Yoshimori, et al. Trimebutine suppresses Toll-like receptor 2/4/7/8/9 signaling pathways in macrophages. Archives of biochemistry and biophysics. 2021. 711. 109029-109029
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MISC (19):
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Books (25):
  • Bidirectional Gene Promoters-Transcription System and Chromosomal Structure, 1st ed.
    Elsevier, USA 2022 ISBN:9780128187876
  • Gene Expression (Ed. Fumiaki Uchiumi)
    IntechOPEN Limited (London) 2022 ISBN:9781803556215
  • Chapter 1 “Introductory Chapter: Gene Expression in Eukaryotic Cells” in "Gene Expression" (Ed. Fumiaki Uchiumi)
    IntechOPEN Limited (London) 2022 ISBN:9781803556222
  • Advances in Medicine and Biology, Vol. 159
    Nova Science Publishers, Inc., Hauppauge, NY 2020 ISBN:9781536171846
  • Gene Expression and Control (Ed. Fumiaki Uchiumi)
    IntechOPEN Limited (London) 2019 ISBN:9781789855173
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Lectures and oral presentations  (254):
  • 「ヒトIDH1及びCDC45遺伝子プロモーターの解析
    (2024年度日本生化学会関東支部例会 2024)
  • Molecular mechanism that controls expression of GGAA motif containing promoter-driven genes
    (BIT’s 13th World Gene Convention-2024 2024)
  • ヒトHDAC10遺伝子プロモーターの酪酸応答性の解析
    (日本薬学会第144年会 2024)
  • 宇宙放射線防護剤開発に向けた反転培養下での放射線細胞応答解析
    (東京理科大学総合研究院スペースシステム創造研究センター第5回宇宙シンポジウム 2024)
  • ヒト網膜オルガノイド迅速分化誘導方法の確立
    (第46回日本分子生物学会年会 2023)
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Education (3):
  • 1989 - 1993 The University of Tokyo Graduate School, Division of Medical Sciences
  • 1987 - 1989 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
  • 1983 - 1987 Tokyo University of Science Faculty of Science Chemistry
Professional career (2):
  • Ph.D (Medical Science) (The University of Tokyo)
  • Ph.D (Pharmaceutical Science) (Tokyo University of Science)
Committee career (1):
  • 2023/04/01 - 2025/03/31 日本基礎老化学会 評議員
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