Rchr
J-GLOBAL ID:200901041704207618   Update date: Sep. 16, 2024

Iwai Shigenori

イワイ シゲノリ | Iwai Shigenori
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.chem.es.osaka-u.ac.jp/bio/
Research field  (3): Molecular biology ,  Synthetic organic chemistry ,  Molecular biochemistry
Research theme for competitive and other funds  (25):
  • 2020 - 2023 Fluorescence detection of cellular ability of mismatch repair using synthetic DNA
  • 2016 - 2021 Higher-order regulatory mechanisms for DNA damage recognition in nucleotide excision repair
  • 2014 - 2016 Mechanisms and functions of i-RNase activity
  • 2013 - 2016 Alternative DNA repair pathways of DNA damage induced by topoisomerase inhibitor
  • 2011 - 2016 Cross-regulation of the maintenance and mutagenesis of genomic sequence and epigenetic information
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Papers (251):
  • Miyako Shiraishi, Noboru Nabeshima, Keiichiro Suzuki, Masatoshi Fujita, Shigenori Iwai. Endonuclease Q as a robust enhancer for nucleic acid amplification. Analytical Biochemistry. 2024. 692. 115569
  • Kazuki Matsubara, Shouta Ueda, Junpei Yamamoto, Shigenori Iwai, Narumi Aoki Shioi, Arato Takedachi, Isao Kuraoka. Structure-specific DNA endonuclease T7 endonuclease I cleaves DNA containing UV-induced DNA lesions. The Journal of Biochemistry. 2024. 176. 1. 35-42
  • Kazuma Mitsuoka, Jung In Kim, Aya Yoshida, Akane Matsumoto, Narumi Aoki-Shioi, Shigenori Iwai, Isao Kuraoka. Base preference for inosine 3′-riboendonuclease activity of human endonuclease V: implications for cleavage of poly-A tails containing inosine. Scientific Reports. 2024. 14. 14973
  • Shigenori Iwai, Yuta Hayashi, Tomohiro Baba, Yasutaka Kitagawa. Acceleration of hydrolytic ring opening of N7-alkylguanine by the terminal carbamoyl group of glycidamide. Chemical Communications. 2024. 60. 38. 5014-5017
  • Naoto Shimizu, Yusaku Hamada, Ryosuke Morozumi, Junpei Yamamoto, Shigenori Iwai, Kei-ichi Sugiyama, Hiroshi Ide, Masataka Tsuda. Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding. Journal of Biological Chemistry. 2023. 104988-104988
more...
MISC (33):
  • Kei Kunimasa, Yuya Bando, Miyako Shiraishi, Emi Aizawa, Kazumi Nishino, Motohiro Tamiya, Takoko Inoue, Hanako Kuhara, Hayato Kawachi, Kika Kuno, et al. Development CRISPR-Cas12-based rapid EGFR mutation detection kit. JOURNAL OF CLINICAL ONCOLOGY. 2020. 38. 15
  • Masayuki Kusakabe, Yuki Onishi, Haruto Tada, Fumika Kurihara, Kanako Kusao, Mari Furukawa, Shigenori Iwai, Masayuki Yokoi, Wataru Sakai, Kaoru Sugasawa. Mechanism and regulation of DNA damage recognition in nucleotide excision repair. Genes and environment : the official journal of the Japanese Environmental Mutagen Society. 2019. 41. 2-2
  • D. Yamada, H. M. Dokainish, T. Iwata, J. Yamamoto, T. Ishikawa, T. Todo, S. Iwai, E. D. Getzoff, K. Yura, A. Kitao, et al. Function conversion between CPD and (6-4) photolyases. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017. 46. S82-S82
  • D. Yamada, H. M. Dokainish, T. Iwata, J. Yamamoto, T. Ishikawa, T. Todo, S. Iwai, E. D. Getzoff, K. Yura, A. Kitao, et al. Function conversion between CPD and (6-4) photolyases. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017. 46. S276-S276
  • D. Yamada, T. Iwata, J. Yamamoto, T. Ishikawa, E. D. Getzoff, T. Todo, S. Iwai, H. Kandori. Asymmetrical functional conversion of (6-4) photolyase and CPD photolyase. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2015. 44. S66-S66
more...
Education (2):
  • 1982 - 1984 Osaka University
  • 1978 - 1982 Osaka University School of Pharmaceutical Sciences
Work history (4):
  • 2001 - 2003 東京大学大学院助教授
  • 1995 - 2001 生物分子工学研究所主任研究員
  • 1988 - 1995 Hokkaido University
  • 1984 - 1988 Hokkaido University
Association Membership(s) (3):
日本化学会 ,  日本分子生物学会 ,  日本薬学会
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