2020 - 2023 Development of microphysiological systems for evaluating inflammation
2019 - 2022 Development of human multicellular spheroidal blood-brain barrier models for drug development studies
2017 - 2020 The construction of a blood-brain barrier model using novel human iPS cell-derived endothelial progenitor cells
2017 - 2019 Development of cancer suicide gene therapy using RNA trans-splicing technology
2015 - 2018 Degradation of glycosaminoglycans in cerebral infarction
2015 - 2017 Development of a novel RNA trans-splicing molecule for cancer gene therapy targeting to cancer-type organic anion transporting polypeptide 1B3
2014 - 2016 Study on the exosomes as a biomarker to estimate in vivo function of human blood-brain barrier
2013 - 2016 Establishment of in vitro and in vivo models for human CES which promote rational development of ester-based prodrugs
2012 - 2015 Expression and functional characterization of cancer-type organic anion transporting polypeptide 1B3 in human lung and colon cancer
2012 - 2014 A challenge to construct human mini liver using temperature sensitive immortalized human liver cells
2009 - 2012 Creation of CYP3A- and P-glycoprotein-humanized mouse and its application to the study of drug metabolism and disposition
2010 - 2011 Characterization of "Ribavirin transportsome" in the small intestine
2009 - 2010 スティーブンス・ジョーンソン症候群モデルマウス創製の試み
2008 - 2009 Characterization of ribavirin uptake systems in hepatocytes and renal tubular cells
Ryohei Hirano, Akitomo Yokokawa, Tomomi Furihata, Hiromi Shibasaki. Plasma 6β-hydroxycortisol to cortisol ratio as a less-invasive cytochrome P450 3A phenotyping method. British journal of clinical pharmacology. 2023
Aya Yamagata, Rena Adachi, Akitomo Yokokawa, Tomomi Furihata, Hiromi Shibasaki. Quantification of fluticasone propionate in human plasma by LC-MS/MS and its application in the pharmacokinetic study of nasal spray at clinical doses. Drug metabolism and pharmacokinetics. 2023. 54. 100541-100541
Huiting Zhang, Dong-Hee Kang, Marie Piantino, Daisuke Tominaga, Takashi Fujimura, Noriyuki Nakatani, J Nicholas Taylor, Tomomi Furihata, Michiya Matsusaki, Satoshi Fujita. Rapid Quantification of Microvessels of Three-Dimensional Blood-Brain Barrier Model Using Optical Coherence Tomography and Deep Learning Algorithm. Biosensors. 2023. 13. 8
横川彰朋, 島崎隼人, 深江桃花, 五十嵐俊二, 秋山遥香, 降幡知巳, 柴崎浩美. Development of a Novel Method for Assessing CYP1A2 Activity Using Endogenous Melatonin Metabolism: Comparison with Caffeine Clearance to Establish an Assessment Method. 日本薬学会年会要旨集(Web). 2024. 144th
猪貝結実, 高田真希, 九原楓香, 横川彰朋, 降幡知巳, 柴崎浩美. Simultaneous determination of 6β-hydroxycortisol and cortisol in human nail by LC-MS/MS for evaluation of CYP3A activity. 日本薬学会年会要旨集(Web). 2023. 143rd
2019/04 - 現在 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
Awards (4)：
2015/11 - 日本薬物動態学会奨励賞
2013/11 - 千葉エリア産学官連携オープンフォーラム2013優秀発表賞
2009/11 - DMPK Editors’ Award for the Most Excellent Article in 2008
2004 - 日本薬学会関東支部会優秀発表賞
Association Membership(s) (8)：
International Brain Barrier Society
, International Society of Studies of Xenobiotics
, 日本分子生物学会
, 日本癌分子標的治療学会
, THE JAPANESE SOCIETY FOR NEUROCHEMISTRY
, THE JAPANESE PHARMACOLOGICAL SOCIETY
, THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS
, THE PHARMACEUTICAL SOCIETY OF JAPAN
