Rchr
J-GLOBAL ID:200901042365103073
Update date: Feb. 01, 2024
Naruse Chie
ナルセ チエ | Naruse Chie
Affiliation and department:
Homepage URL (1):
http://www.anim.med.kyoto-u.ac.jp/research/index.html
Research field (3):
Developmental biology
, Laboratory animal science
, Animals: biochemistry, physiology, behavioral science
Research keywords (5):
マウス
, 糖鎖
, 発生
, エピジェネティクス
, 疾患モデル動物
Research theme for competitive and other funds (20):
- 2021 - 2024 時期および組織特異的なプロテインノックダウンを可能とするデグロンシステムの開発
- 2021 - 2024 Analysis of galactose carbohydrates regulating homing and differentiation of HSC in the bone marrow niche
- 2020 - 2024 Development of degron system for cancer therapy
- 2018 - 2021 Establishment of a novel cancer therapy using degron system in mice
- 2017 - 2020 Functions of B4galt1 in the homing of hematopoietic stem cells.
- 2016 - 2019 Study on neurological disorder caused by ganglioside-deficiency and therapeutics by glycolipid supplement
- 2016 - 2019 Establishment of new mental disease model mouse by heterochromatin factor HP1 deficiency
- 2016 - 2019 Attempt to establish totipotent stem cells using degron system
- 2015 - 2018 Analysis of gut microbiota and gut immunity in the development of IgA nephropathy using its mouse model
- 2013 - 2016 Analysis of brain functions regulated by histone modification and development of psychiatric disorder animal models
- 2013 - 2016 The roles of histone modifications in the perinatal period.
- 2011 - 2012 生殖細胞の発生・分化においてヒストン修飾因子が果たす制御機構の解析
- 2010 - 2011 Analyses of mutant mice lacking histone modification factors.
- 2009 - 2010 始原生殖細胞の初期分化におけるHP1γとヒストン修飾の機能解析
- 2008 - 2009 Analyses of infertility of HP1γ mutant mice
- 2006 - 2007 生殖細胞のインプリンティングおよび減数分裂におけるHP1γの機能解明
- 2006 - 2007 EphA2/EphA4変異マウスを用いた腎嚢胞性疾患発症の分子メカニズムの解明
- 2005 - 2006 β4-ガラクトース転移酵素-I欠損によるIga腎症発症機構の解析
- 2003 - 2004 ORC4変異マウスを用いた個体レベルでの細胞周期研究
- 2002 - 2003 改良遺伝子トラップ法による新規発生制御遺伝子の単離と機能解析
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Papers (26):
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Heng Wei, Chie Naruse, Daisuke Takakura, Kazushi Sugihara, Xuchi Pan, Aki Ikeda, Nana Kawasaki, Masahide Asano. Beta-1,4-galactosyltransferase-3 deficiency suppresses the growth of immunogenic tumors in mice. Frontiers in immunology. 2023. 14. 1272537-1272537
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Chie Naruse, Kazushi Sugihara, Tatsuhiko Miyazaki, Xuchi Pan, Fumihiro Sugiyama, Masahide Asano. A degron system targeting endogenous PD-1 inhibits the growth of tumor cells in mice. NAR cancer. 2022. 4. 2. zcac019
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Mengnan Li, Shin-Ya Nishio, Chie Naruse, Meghan Riddell, Sabrina Sapski, Tatsuya Katsuno, Takao Hikita, Fatemeh Mizapourshafiyi, Fiona M Smith, Leanne T Cooper, et al. Digenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome. Nature communications. 2020. 11. 1. 1343-1343
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Chie Naruse, Kanae Abe, Toru Yoshihara, Tomoaki Kato, Takumi Nishiuchi, Masahide Asano. Heterochromatin protein 1γ deficiency decreases histone H3K27 methylation in mouse neurosphere neuronal genes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020. 34. 3. 3956-3968
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Soichiro Takagaki, Rieko Yamashita, Noriyoshi Hashimoto, Kazushi Sugihara, Kanako Kanari, Keisuke Tabata, Toshikazu Nishie, Shogo Oka, Masanori Miyanishi, Chie Naruse, et al. Galactosyl carbohydrate residues on hematopoietic stem/progenitor cells are essential for homing and engraftment to the bone marrow. Scientific reports. 2019. 9. 1. 7133-7133
more...
MISC (3):
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遺伝子トラップ法. 生物工学会誌. 2003. 81. 8. 351-354
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S Nakae, C Naruse-Nakajima, K Sudo, R Horai, M Asano, Y Iwakura. IL-1 alpha but not IL-1 beta, is required for contact-allergen-specific T cell activation during the sensitization phase in contact hypersensitivity. JOURNAL OF LEUKOCYTE BIOLOGY. 2001. 95-95
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NARUSE-NAKAJIMA Chie, ASANO Masahide, IWAKURA Yoichiro. Analysis of EphA2 receptor tyrosine kinase disrupted mice by gene trap retroviral insertion. 1998. 21. 602-602
Patents (1):
Education (3):
- 1995 - 2001 The University of Tokyo
- 1993 - 1995 The University of Tokyo Faculty of Science Department of Biological Sciences
- 1991 - 1993 The University of Tokyo College of Arts and Sciences
Professional career (1):
Work history (5):
- 2018/04 - 現在 Kyoto University Institute of Laboratory Animals, Graduate School of Medicine
- 2015/01 - 2018/03 Kyoto University Institute of Laboratory Animals, Graduate School of Medicine
- 2003/10 - 2014/12 Kanazawa University Advanced Science Research Center
- 2001 - 2003 : Kanazawa University
- 2003 - -: Kanazawa University
Committee career (2):
- 2020/07 - 現在 日本実験動物学会 評議員
- 2018/04 - 現在 日本実験動物学会 Experimental Animals編集委員
Awards (1):
Association Membership(s) (4):
日本分子生物学会
, JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE
, JAPANESE ASSOCIATION FOR EXPERIMENTAL ANIMAL TECHNOLOGISTS
, 日本エピジェネティクス研究会
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