Chihiro Koshimoto

Research keywords (2)：保全生物学 , 実験動物学

Research theme for competitive and other funds (23)：

2021 - 2027 外部検証推進のための人材の育成と活用
2022 - 2026 Development of novel animal models for late onset Alzheimer's disease and body fluid omics analysis
2022 - 2024 高浸透圧傷害克服による魚類と両生類の卵子の凍結保存
2019 - 2023 Research on establishment of information dissemination base to gain social understanding of animal experiment
2020 - 2022 Trial for cryopreservation of fish oocytes

2019 - 2022 Do sperm preselect the sex of Japanese spiny rats (Genus Tokudaia) which lost their Y chromosome?

2016 - 2021 外部検証のための人材育成

2017 - 2020 The establishment of diagnostic tool for causative microorganisms using laser capture microdissection

2017 - 2020 「奄美・琉球における遺産価値の高い深林棲絶滅危惧種に対応する保全技術開発」

2016 - 2019 Research on the way of information transmission to gain social understanding of animal experiments

2014 - 2019 The qualitative validation in the unique wild rodents origin bio-resource such as genus Apodemus, which contains Japanese endemic and European common species

2014 - 2017 A trial to overcome the injury caused by chilling/heat stress in oocytes/embryos by controlling temperature-sensitive channel activities

2013 - 2016 A novel diagnostic method of causative agents for infectious diseases using animal inoculation and genomic analysis

2011 - 2014 The improvement of the tolerance of mammalian oocytes to cryopreservation by inducing endogenous expression of water/cryoprotectant channels or by gating the channels

2011 - 2014 Development of the cryopreservation method for fish oocytes and ovaries

2011 - 2013 Construction of original research infrastructure to investigate life phenomenon of great diversity

2009 - 2011 The creation and application of lifestyle-related diseases in the hyperlipidemia mouse.

2008 - 2010 Cryopreservation of oocytes and embryos by inducing the expression of cryoprotectant channels.

2007 - 2009 Cryopreservation of laboratory fish oocytes

2007 - 2009 Utilization of the high pressure freezing as a gamete cryopreservation procedure for mammalian bio-resource maintenances

2005 - 2006 生理的溶液を用いた生殖細胞の高圧ガラス化凍結:究極の凍結保存法を目指して

2004 - 2006 The modulation of the tolerance of oocytes to cryopreservation by artificial expression of water channels -vertebrates and invertebrates-

2003 - 2004 Basic research for non-toxic cryopreservation of mammalian gamete without a use of membrane permeable cryoprotectants.

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Papers (64)：

Yuki IKAI, Goro A. NAGURA-KATO, Shinsuke H. SAKAMOTO, Akio SHINOHARA, Chihiro KOSHIMOTO. Optimization of inhaled anesthesia for <i>Octodon degus</i> using electroencephalography. Experimental Animals. 2025
Hiroko Ishiniwa, Tsukasa Okano, Daiji Endoh, Hideo Hirayama, Akira Yoshioka, Yasushi Yokohata, Junji Shindo, Chihiro Koshimoto, Akio Shinohara, Shinsuke H. Sakamoto, et al. Oxidative stress on the male reproductive organs of wild mice collected from an area contaminated by radioactive materials in Fukushima. Scientific Reports. 2024. 14. 1
Yoshinobu Uno, Kazumi Matsubara, Jun Inoue, Johji Inazawa, Akio Shinohara, Chihiro Koshimoto, Kenji Ichiyanagi, Yoichi Matsuda. Diversity and Evolution of Highly Repetitive DNA Sequences Constituting Chromosome Site-Specific Heterochromatin in Two Gerbillinae Species. Cytogenetic and Genome Research. 2023. 1-10
Rina Ukyo, Akio Shinohara, Chihiro Koshimoto, Goro A. Nagura-Kato, Seiji Ieiri, Yasuhiro Tsuzuki, Shinsuke H. Sakamoto. Long-term behavioral effects of social separation during early life in a social mammal, Octodon degus. Scientific Reports. 2023. 13. 1
Shinichiro Shirouzu, Naohiro Sugita, Narantsog Choijookhuu, Yu Yamaguma, Kanako Takeguchi, Takumi Ishizuka, Mio Tanaka, Fidya Fidya, Kengo Kai, Etsuo Chosa, et al. Pivotal role of High-Mobility Group Box 2 in ovarian folliculogenesis and fertility. Journal of ovarian research. 2022. 15. 1. 133-133

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MISC (55)：

緒方穂波, 前山賢太, 林扶充子, 仮屋博敬, 川辺敏晃, 名倉悟郎, 城ヶ原貴通, 篠原明男, 越本知大. 稀少固有種アマミトゲネズミの実験動物化に向けた飼育ストレス評価の試み. 九州実験動物雑誌. 2019. 35
Jogahara Takamichi, Koshimoto Chihiro, Yasuda Masatoshi, Kotaka Nobuhiko, Kuroiwa Asato. Recent research on Tokudaia IV -A bridge between conservation and life sicence-. Mammalian Science. 2018. 58. 1. 103-104
中村鉄平, 中村鉄平, 市居修, 入江隆夫, 篠原明雄, 孝口裕一, 越本知大, 長崎健一, 寸田祐嗣, ELEWA Yaser Hosny, et al. 雌性コットンラットの胸腺にみられる加齢性変化. 日本獣医学会学術集会講演要旨集. 2017. 160th. 309-309
Atsushi Yamashita, Yunosuke Matsuura, Yan Zhao, Takashi Iwakiri, Kazuaki Yamasaki, Chihiro Sugita, Chihiro Koshimoto, Kazuo Kitamura, Keiichi Kawai, Nagara Tamaki, et al. Alteration of Glycolysis Metabolite Levels and Impaired Hypoxic Response in Diabetic Atherosclerosis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017. 37
篠原明男, 稲留健人, 江藤毅, 加藤悟郎, 大久保慶信, 坂本信介, 越本知大. アカネズミおよびヒメネズミの消化管内微生物叢の比較. 日本哺乳類学会大会プログラム・講演要旨集. 2016. 2016. 147

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Education (2)：

- 1992 Kyoto University
- 1986 Kyoto University Faculty of Agriculture

Work history (16)：

2021/10 - 現在 University of Miyazaki Frontier Science Research Center
2018/04 - 現在 University of Miyazaki Faculty of Agriculture
2008/06 - 現在 - 宮崎大学フロンティア科学実験総合センター実験支援部門生物資源分野教授
2007/04 - 2008/05 University of Miyazaki Frontier Science Research Center
2003/10 - 2007/03 University of Miyazaki Frontier Science Research Center

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Committee career (35)：

2020/05 - 現在日本実験動物学会理事
2017/01 - 現在環境省トゲネズミ生息域外保全検討作業部会専門員
2016/05 - 現在日本実験動物学会広報・情報公開検討委員会
2016/05 - 現在日本実験動物学会外部検証委員会
2016/05 - 現在国立大学法人動物実験施設協議会検証委員会

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Awards (1)：

2020/04 - 文部科学省文部科学大臣表彰外部検証体制の構築と実施による適正な動物実験の普及啓発

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