Rchr
J-GLOBAL ID:200901043316073114
Update date: Mar. 05, 2025 Yokoyama Toshifumi
ヨコヤマ トシフミ | Yokoyama Toshifumi
Affiliation and department: Job title:
Assistant Professor
Homepage URL (1): http://www.ans.kobe-u.ac.jp/kenkyuuka/sigen/bunsi.html Research field (1):
Zoological sciences
Research keywords (8):
組織学
, マウス
, セルトリ細胞
, 遺伝学
, 性分化疾患
, 性分化
, Histology
, 組織細胞生物学
Research theme for competitive and other funds (18): - 2024 - 2027 鳥類特異的な飲水調節機構の解明~進化の過程で獲得した渇きに耐えるための秘策~
- 2022 - 2026 妊娠母体炎症が惹起する児の脳-身体の双方向性制御機能の破綻
- 2022 - 2025 Elucidation of mechanisms of generational toxicology of developmental neurotoxicity - Developmental program and epigenomic toxicity of pesticides
- 2024 - 2025 Elucidation of mechanisms of transgenerational effects of developmental neurotoxicity - Developmental program and epigenomic toxicity of pesticides
- 2021 - 2024 Developmental neurotoxicity of pesticides based on the transgenerational inheritance and localized neural progenitor and glial cells activity
- 2019 - 2022 殺虫剤の「生物学的モニタリン グに基づく適応的リスク評価法 」の開発と実践
- 2018 - 2022 腸内細菌叢と脳との双方向情報伝達機構の解明-ストレスによる肥満易発症の分子基盤
- 2017 - 2020 哺乳類の未分化生殖腺の雄性化を制御するY染色体のエピジェネティック修飾の解明
- 2016 - 2019 哺乳類性腺の性差構築と性特異的エピゲノム制御・維持機構の分子基盤の解明
- 2014 - 2018 脳が統合するエネルギー代謝調節機構-ストレスによる肥満易発症の分子機序-
- 2014 - 2017 生殖腺の性特異的分化に関わる細胞特異的エピジェネティック修飾の時空間的変化
- 2012 - 2015 生殖腺の性差構築とその破綻機構における細胞・組織特異的エピゲノム制御
- 2011 - 2014 Regulation mechanism of mammalian sex differentiation and disorders of sex development
- 2010 - 2014 周生期ストレスと生活習慣病発症機序に関する研究-脳と脂肪組織のクロストーク解析-
- 2006 - 2010 Cytoarchitectural changes of brain induced by alcohol exposure : effects on Notch signal pathway
- 2006 - 2010 Effects of maternal care on brain development : molecular mechanism of mother-infant interactions
- 2002 - 2006 Involvement of reward system in acquisition and maintenance of alcohol independence.
- 2002 - 2005 Effects of Maternal Deprivation on Brain Development in Rats
Show all
Papers (127): -
Sarika NUNOBIKI, Ayano YOSHIMOTO, Makiko ITO, Sakura YONOICHI, Yukako HARA, Yuya ISHIDA, Rinako MORISHITA, Youhei MANTANI, Toshifumi YOKOYAMA, Tetsushi HIRANO, et al. Effect of the neonicotinoid pesticide clothianidin at a no-observed-adverse-effect-level (NOAEL) dose on maternal behavior in pregnant mice and their female offspring. Journal of Veterinary Medical Science. 2025. 87. 4
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Ayano YOSHIMOTO, Sarika NUNOBIKI, Makiko ITO, Sakura YONOICHI, Yukako HARA, Yuya ISHIDA, Youhei MANTANI, Toshifumi YOKOYAMA, Tetsushi HIRANO, Yoshinori IKENAKA, et al. Effects of low-dose subchronic exposure to the phenylpyrazole insecticide fipronil in juvenile mice. Journal of Veterinary Medical Science. 2025. 87. 4
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Shota Murase, Youhei Mantani, Nobuhiko Ohno, Asaka Shimada, Satoki Nakanishi, Rinako Morishita, Toshifumi Yokoyama, Nobuhiko Hoshi. Regional differences in the ultrastructure of mucosal macrophages in the rat large intestine. Cell and tissue research. 2024
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Tetsushi Hirano, Shuji Ohno, Yoshinori Ikenaka, Kanoko Onaru, Shizuka Kubo, Yuka Miyata, Mizuki Maeda, Youhei Mantani, Toshifumi Yokoyama, Collins Nimako, et al. Quantification of the tissue distribution and accumulation of the neonicotinoid pesticide clothianidin and its metabolites in maternal and fetal mice. Toxicology and applied pharmacology. 2024. 116847-116847
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Yukako Hara, Asuka Shoda, Sakura Yonoichi, Yuya Ishida, Midori Murata, Mako Kimura, Makiko Ito, Sarika Nunobiki, Ayano Yoshimoto, Youhei Mantani, et al. No-observed-adverse-effect-level (NOAEL) clothianidin, a neonicotinoid pesticide, impairs hippocampal memory and motor learning associated with alteration of gene expression in cerebellum. The Journal of veterinary medical science. 2024
more... Books (6): - 獣医組織学 改訂第9版-第4章 血液及び骨髄(骨髄)
学窓社 2023
- 獣医組織学 改訂第9版-第19章 家禽の組織学(1.血液,2.骨髄)
学窓社 2023
- 獣医組織学 改訂第8版-第19章 家禽の組織学(1.血液,2.骨髄)
学窓社 2020
- 獣医組織学 改訂第8版-第4章 血液及び骨髄(骨髄)
学窓社 2020
- 獣医組織学 改訂第7版-第4章 血液及び骨髄(骨髄)
学窓社 2017
more... Lectures and oral presentations (299): -
Histological analysis of reproductive tract formation disorders in B6N-XYPOS mice
(APPW2025)
-
マウスにおけるフェニルピラゾール系農薬フィプロニルの胎子・新生子期曝露の次世代影響
(日本内分泌撹乱物質学会第26回研究発表会 2024)
-
ネオニコチノイド系農薬クロチアニジンの無毒性量(NOAEL)曝露による母性行動への継世代影響
(日本内分泌撹乱物質学会第26回研究発表会 2024)
-
クロチアニジン父性曝露による精子microRNAの発現変動と神経行動学的な次世代影響
(日本内分泌撹乱物質学会第26回研究発表会 2024)
-
「Developmental neurotoxicity of fetal and neonatal exposure to the phenylpyrazole pesticide fipronil in mice
(8th International Chemical Hazard Symposium 2024)
more... Education (1): - - 2003 Kobe University Graduate School of Science and Technology
Professional career (2): - 修士(農学) (神戸大学)
- 博士(農学) (神戸大学)
Work history (1): - Former Institution /Organization Kagawa University Faculty of Medicine School of Medicine Research Associate
Awards (1): - 2010/07 - 日本先天異常学会 第50回日本先天異常学会学術集会 優秀ポスター賞 Sry 導入XXマウスにおける雄性生殖腺の形態学的解析
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