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J-GLOBAL ID：200901044806396635   Update date: Mar. 24, 2025

KUWAHARA Masayasu

クワハラ マサヤス | KUWAHARA Masayasu
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Affiliation and department：
Nihon University College of Humanities and Sciences Department of Chemistry

About Nihon University College of Humanities and Sciences Department of Chemistry


Job title： Professor
Homepage URL  (2)： http://kuwaharaken.org/ ,  http://eng.kuwaharaken.org/
Research field  (4)： Biochemistry ,  Molecular biochemistry ,  Chemical biology ,  Analytical chemistry
Research keywords  (5)： Isothermal Signal Amplification ,  Molecular Probe ,  Xeno Nucleic Acid ,  Nucleic Acid Aptamer ,  Bioanalysis
Papers (95)：
  • Yilei Wang, Mohan Amarasiri, Wakana Oishi, Masayasu Kuwahara, Yuka Kataoka, Hiroki Kurita, Fumio Narita, Rong Chen, Qian Li, Daisuke Sano. Aptamer-based biosensors for wastewater surveillance of influenza virus, SARS-CoV-2, and norovirus: A comprehensive review. Water Research. 2025. 123484-123484
  • Masumi Taki, Masayasu Kuwahara, Chaohui Li, Naoko Tomoda, Naoyuki Miyashita, Tetsuo Kan, Jay Yang. ARCaDia: single-round screening of a DNA-type targeted covalent binder possessing a latent warhead. Chemical Communications. 2024. 60. 100. 14964-14967
  • Tomoko Wariishi, Yuka Kataoka, Tomoaki Nakamura, Yuuya Kasahara, Masataka Kuroda, Satoshi Obika, Masayasu Kuwahara. Lantern-type G-quadruplex fluorescent sensors for detecting divalent metal ions. Analytical Biochemistry. 2024. 690. 115525-115525
  • Hiroki Hayashi, Akihiro Enami, Hiroto Fujita, Shigeki Kuroiwa, Keishi Ohashi, Masayasu Kuwahara, Tetsuya Osaka, Toshiyuki Momma. Field-effect transistor biosensor with signal amplification by ternary initiation complexes for detection of wide-range RNA concentration. Talanta. 2024. 273. 125846-125846
  • Kunihiko Morihiro, Osamu Hasegawa, Yuuya Kasahara, Shohei Mori, Tatsuro Kasai, Masayasu Kuwahara, Satoshi Obika. Azobenzene-modified DNA aptamers evolved by capillary electrophoresis (CE)-SELEX method. Bioorganic and Medicinal Chemistry Letters. 2021. 31
ｍore...
Patents (49)：
  • EP3957733(Germany, United Kingdom, France)
  • No.7565572(Japan)
  • ZL202210227991.1(China)
  • No.7448239(Japan)
  • US11643660(USA)
ｍore...
Books (13)：
  • Handbook of chemical biology of nucleic acids (edited by Naoki Sugimoto)
    Springer, Singapore 2022 ISBN:9789811613135
  • CSJ current review: Evolving nucleic acid chemistry (edited by Chemical Society of Japan)
    Kagaku-Dojin Publishing Co., Inc. 2021 ISBN:9784759814019
  • Handbook for nucleic acid science (supervised by Japan Society of Nucleic Acids Chemistry, edited by Naoki Sugimoto)
    Kodansha Scientific, Ltd. 2020 ISBN:9784065207864
  • CSJ current review: Controlling biomolecular reactions (edited by Chemical Society of Japan)
    Kagaku-Dojin Publishing Co., Inc. 2020 ISBN:9784759813968
  • Synthesis technology of peptides, nucleic acids and sugar chains for medium molecule drug discovery (supervised by Kazuhiro Chiba)
    CMC Publishing CO., LTD. 2018 ISBN:9784781313207
ｍore...
Lectures and oral presentations  (25)：
  • Enhanced selectivity over topology and altered targeting by fluorescent G4 binder modifications
    (Asian 3 Roundtable on Nucleic Acids 2024 (A3RONA 2024), Nov 2, 2024 2024)
  • Fluorescent binders with enhanced selectivity for G-quadruplex topologies
    (Advances in Noncanonical Nucleic Acids (ANNA 2024), Oct 26, 2024 2024)
  • Halfway through the development of technology to create molecular recognition polymers that function in water
    (Supra FIBER International Summit for Nucleic Acids (S-FISNA) 2024)
  • Modified nucleic acid aptamer selections using polymerase variants and substrate analogs
    (Asian 3 Roundtable on Nucleic Acids 2023 (A3RONA 2023), Nov 11, 2023 2023)
  • Modified substrates and polymerase variants for functional xeno nucleic acid selections
    (FIBER International Summit for Nucleic Acids 2023 (FISNA2023) 2023)
ｍore...
Education (3)：
  • - 1999 Okayama National University Graduate School of Natural Science and Technology Doctoral Program
  • - 1996 Okayama National University Graduate School of Engineering Master Degree Program
  • - 1994 Okayama National University Faculty of Engineering Department of Biological Functions Engineering
Professional career (1)：
  • PhD (Okayama National University)
Work history (9)：
  • 2018/04 - 現在 Nihon University Department of Chemistry, College of Humanities and Sciences Professor
  • 2013/04 - 2018/03 Gunma University, National University Corporation Graduate School of Science and Technology Associate Professor
  • 2009/12 - 2013/03 Gunma University, National University Corporation Graduate School of Engineering Associate Professor
  • 2007/04 - 2009/11 Gunma University, National University Corporation Graduate School of Engineering Assistant Professor
  • 2004/10 - 2008/03 Japan Science and Technology Agency (JST) Strategic Basic Research Program (PRESTO) PRESTO Researcher (concurrent post)
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Awards (1)：
  • 2009/04 - Minister of Education, Culture, Sports, Science and Technology Commendation Young Scientists' Prize
Association Membership(s) (7)：
Japan Society of Nucleic Acids Chemistry (JSNAC) ,  Japan Society for Analytical Chemistry (JSAC) ,  International Society for Nucleosides, Nucleotides and Nucleic Acids (IS3NA) ,  American Chemical Society (ACS) ,  Forum on Biomolecular Chemistry (FBC) ,  Society of Polymer Science, Japan (SPSJ) ,  Chemical Society of Japan (CSJ)
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