Rchr
J-GLOBAL ID：200901045017985584
Update date: Jul. 17, 2024 Yano Yoshiaki
ヤノ ヨシアキ | Yano Yoshiaki
Research field (1)：
Pharmaceuticals - analytical and physicochemistry
Research keywords (1)：
生体膜の生物物理学
Research theme for competitive and other funds (16)： - 2019 - 2022 Effects of amino acid sequence and lipids on the structure and self-association of transmembrane helices
- 2019 - 2021 High resolution NMR structure determination of membrane proteins using novel phospholipid analogs
- 2018 - 2021 Development of a small-sized labeling method for membrane proteins and its application for heterooligomer analysis
- 2017 - 2019 Novel Phospholipid Analogs for NMR Structural Determination of Membrane Proteins
- 2016 - 2019 Development of helix-anchored planar membrane
- 2014 - 2016 Development of phospholipid analogs for stable solubilization of membrane proteins and application for high resolution NMR analysis
- 2013 - 2016 Association dynamics of transemrbane helices detected by single-molecle FRET
- 2012 - 2015 Application of novel labeling method for membrane proteins to aggregational analysis and its sophistication
- 2012 - 2014 Development of novel nano discs for structural analysis of membrane proteins
- 2011 - 2012 Analysis of structural change and ligand binding of membrane receptors by single molecule spectroscopy
- 2009 - 2011 Visualization and analysis of receptor oligomerization in living cells by using novel fluorescence labeling method
- 2009 - 2010 一分子蛍光計測による膜タンパク質構造形成過程の揺らぎ解析
- 2008 - 2009 Crosslinking and miniaturization of protein labeling method in living cells based on coiled-coil formation
- 2006 - 2007 モデル膜貫通へリックスを用いた膜タンパク質フォールディング駆動力の計測
- 2003 - 2004 膜タンパク構造形成原理の解明を目指したヘリックス間・ヘリックス-脂質間力の計測
- モデル膜貫通ヘリックスによる膜タンパク質フォールディング駆動力の解明
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Ruka Yamauchi, Kenichi Kawano, Yousuke Yamaoka, Aoi Taniguchi, Yoshiaki Yano, Kiyosei Takasu, Katsumi Matsuzaki. Development of Antimicrobial Peptide-Antibiotic Conjugates to Improve the Outer Membrane Permeability of Antibiotics Against Gram-Negative Bacteria. ACS infectious diseases. 2022
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Takumi Kaji, Yoshiaki Yano, Katsumi Matsuzaki. In-Cell FRET Indicates Magainin Peptide Induced Permeabilization of Bacterial Cell Membranes at Lower Peptide-to-Lipid Ratios Relevant to Liposomal Studies. ACS Infectious Diseases. 2021. 7. 10. 2941-2945
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Hayato Itaya, Kota Kasahara, Qilin Xie, Yoshiaki Yano, Katsumi Matsuzaki, Takuya Takahashi. All-Atom Molecular Dynamics Elucidating Molecular Mechanisms of Single-Transmembrane Model Peptide Dimerization in a Lipid Bilayer. ACS Omega. 2021. 6. 17. 11458-11465
- Yoshiaki Yano, Yuta Watanabe, Katsumi Matsuzaki. Thermodynamic and kinetic stabilities of transmembrane helix bundles as revealed by single-pair FRET analysis: Effects of the number of membrane-spanning segments and cholesterol. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2021. 1863. 3. 183532-183532
- Erika Azuma, Naoki Choda, Mayu Odaki, Yoshiaki Yano, Katsumi Matsuzaki. Improvement of Therapeutic Index by the Combination of Enhanced Peptide Cationicity and Proline Introduction. ACS Infectious Diseases. 2020. 6. 8. 2271-2278
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N. Fukada, Y. Yano, K. Matsuzaki. PEPTIDE-BASED LIPOSOME-CELL FUSION SYSTEM FOR CELLULAR DELIVERY OF LIPOSOMAL COMPONENTS. JOURNAL OF PEPTIDE SCIENCE. 2016. 22. S112-S112
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Naoya Itoh, Eri Takada, Yoshiaki Yano, Masaru Hoshino, Katsumi Matsuzaki. Relationship between Aggregation of Amyloid-beta Protein on Cells and Cytotoxicity. BIOPHYSICAL JOURNAL. 2016. 110. 3. 219A-219A
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N. Itoh, E. Takada, Y. Yano, M. Hoshino, K. Matsuzaki. Identification of toxic A beta aggregates and cross seeding between A beta 40 and A beta 42 on neuronal cells. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2015. 44. S246-S246
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Yuki Okada, Hiroshi Ueno, Yoshiaki Yano, Masaru Hoshino, Hikari Itoh-Watanabe, Akira Naito, Katsumi Matsuzaki. The Presence of Antiparallel Beta-Sheets in Toxic Fibrils Formed by ABeta on GM1 Clusters. BIOPHYSICAL JOURNAL. 2015. 108. 2. 547A-547A
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Yoshiaki Yano, Kotaro Kondo, Katsumi Matsuzaki. Single-Molecule FRET Detection of GXXXG-Mediated Transmembrane Helix-Helix Interactions. BIOPHYSICAL JOURNAL. 2015. 108. 2. 500A-500A
ｍore...- 新規蛍光標識法を用いた創薬ターゲット膜受容体のイメージング解析
ナノバイオ技術と最新創薬応用研究 、35-39、メディカルドゥ 2012
- 特異的蛍光ラベル法による生細胞での受容体イメージング
薬学分析科学の最前線, 170-171,じほう 2009
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生細胞におけるアミロイド前駆体タンパク質の会合状態解析
(2015)
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共有結合型コイルドコイルラベル法の確立とグリコフォリンAの会合状態解析
(日本薬学会第135年会 2015)
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Single-molecule FRET detection of GXXXG-mediated transmembrnae helical interactions
(Biophysical society 59th annual meeting 2015)
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The presence of antiparallel beta-sheets in toxic fibrils formed by abeta on GM1 clusters
(2015)
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マイクロアレイを用いたアミロイドbeta蛋白質による細胞死メカニズムの考察
(第36回生体膜と薬物の相互作用シンポジウム 2014)
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