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J-GLOBAL ID：200901045375969957 Update date: Jan. 10, 2025

Kuroda Reiko

クロダレイコ | Kuroda Reiko

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Affiliation and department：
Job title： Senior Research Professor / Distinguished Professor

Research field (8)： Developmental biology , Cell biology , Biochemistry , Functional solid-state chemistry , Inorganic and coordination chemistry , Bioorganic chemistry , Structural/physical organic chemistry , Basic physical chemistry

Research keywords (9)： suptramolecular chemistry , solid state chemistry , CD spectroscopy , snail handedness , chiromorphology , developmental biology , chiroptical spectroscopy , Instrumentation , chiral solid-state chemistry

Research theme for competitive and other funds (30)：

2021 - 2023 住血吸虫症の克服に向けて - 中間宿主の自然免疫機構をゲノム編集で解明
2017 - 2022 Developments of Thermomechanical Properties of Soft Crystals
2017 - 2019 Dynamic analyses of cell-fate determination and cell specification at the molecular level
2012 - 2015 Chirality amplification through unique crystallization - supersaturated solution, melt and crystal co grinding
2012 - 2015 Nonclassical control of chiral optical properties in chiral supramolecular organic fluorophore

2012 - 2014 Towards the creation of transgenic snails for the identification of the handedness determining gene

2010 - 2014 Emerging optical activity based on molecular parity violation hypothesis

2008 - 2012 Antitumor mechanism in molecular model with relation to fluctuation of tumor cell membranes and liposomes

2004 - 2010 カイロモルフォロジー:物質界・生物界における分子から分子集合体の構築

2009 - 2010 アミロイドーシス関連タンパク質の分子ダイナミクス

1999 - 2004 黒田カイロモルフォロジープロジェクト

1998 - 2000 Chasing chirality recognition reaction in the solid-state

1997 - 2000 DNA-ligand interactions studied through the chiral nature of DNA

1998 - 1999 Pattern and process of chiral evolution in snails.

1995 - 1995 有機金属化合物によるDNA塩基配列の認識

1995 - 1995 腫瘍をターゲットとした新規ランタノイド化合物の開発

1994 - 1995 Novel metal complex oligomer which forms triple helix with DNA

1994 - 1994 有機金属化合物によるDNA塩基配列の認識-機構の解明と新化合物の開発

1991 - 1993 The chirality of metal complexes recognized by DNA and its significance towards biological activities

1992 - 1992 新しい多機能金属錯体によるDNA鎖切断機構の解明

1991 - 1991 新しい多機能金属錯体によるDNA鎖切断機構の解明

1989 - 1990 Studies on Stereoselectivities on a Clay Surface by STM Method

1989 - 1990 Multi-Functional Metal Complexes with DNA Base-Sequence Selectivity

1989 - 1990 Development of Sugar Transformation System Using New Complex Catalysis

1987 - 1987 ras発癌遺伝子産物p21の構造と機能

1987 - 1987 核酸と金属錯体の分子レベルでみた相互作用

1986 - 1987 Multi-dimensional Metal Complexes as Separation-Reaction Media

キラル固体化学、固体状態測定用全偏光対応型分光計の開発、超分子構造による光学分割。巻貝の巻型決定遺伝子の同定と決定機構の解明

enantioselective solid-state reactions, optical resolution by spuramolecular crystal formation, solid-state CD spectroscopy and instrumentaition. identification of the snail handednes-determinin gene and the mechanism.

Solid-state chiral chemistry, Instrumentation of chiropotical spectroscopy, Optical resolution by supramolecular crystallization, Enantioselective solid-state reactions, Identification of L. stagnalis handedness determining single gene and the mechanism

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Papers (366)：

Reiko Kuorda. LR asymmetry in invertebrates: From molecules to organisms. Annual Review of Cell and Developmental Biology. 2024. 40. 97-117
Reiko Kuroda, Takunori Harada, Hiromi Takahashi. Fast and artifact-free circular dichroism measurement of solid-state structural changes. Chirality. 2024. 36. 1. 1-11
Clément Pinètre, François-Xavier Gendron, Reiko Kuroda, Ryusei Oketani, Christian Aupetit, Thierry Buffeteau, Gérard Coquerel. Use of Conglomerate Mixed Crystals to Deracemize a Stable Racemic-Compound-Forming System. Chemistry - A European Journal. 2023. 29. 27
Reiko Kuroda. Exploring the structural difference in homologous proteins that are crucial in organismal body handedness determination. Sogo-Kogaku,. 2022. 34. 38-45
Reiko Kuroda. Through the Looking-glass: From Molecules to Crystals and snails. The Carrollian. 2021. 35-36. 119-131

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MISC (237)：

秋元文, 蓮池英里香, 黒田玲子, 松川滉, 蛭田勇樹, 金澤秀子, 吉田亮. 固体円二色性測定で解明する温度応答性高分子ゲル内でのDNA立体構造制御. 日本分析化学会年会講演要旨集. 2017. 66th. 117
蓮池英里香, 秋元文, 黒田玲子, 松川滉, 蛭田勇樹, 金澤秀子, 吉田亮. 温度応答性PNIPAAmゲルの相転移を利用したDNAアプタマーの立体構造制御. 高分子ゲル研究討論会講演要旨集. 2017. 28th. 105-106
秋元文, 蓮池英里香, 黒田玲子, 松川滉, 蛭田勇樹, 金澤秀子, 吉田亮. 温度応答性ゲルの相転移を駆動力としたssDNAの立体構造制御. インテリジェント材料・システムシンポジウム講演要旨集. 2017. 26th. 19
秋元文, 蓮池英里香, 黒田玲子, 蛭田勇樹, 金澤秀子, 松川滉, 吉田亮. 温度応答性ゲルの相転移を駆動力としたDNAアプタマーの構造制御. 日本バイオマテリアル学会シンポジウム予稿集. 2016. 2016. 106
秋元文, 蓮池英里香, 黒田玲子, 蛭田勇樹, 金澤秀子, 吉田亮. PNIPAAmゲルの相転移を駆動力としたDNAアプタマー構造制御. 高分子学会予稿集(CD-ROM). 2016. 65. 2. ROMBUNNO.1W03

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Books (1)：

Chiral Luminescence: From Molecules to Materials and Devices
Edited by K. Akagi, Willey-VCH. Inc 2024

Education (3)：

1972 - 1975 The University of Tokyo Graduate School of Science Department of Chemistry, Ph.D. course
1970 - 1972 The University of Tokyo Graduate School of Science Department of Chemistry, M.Sc. course
1966 - 1970 Ochanomizu University Faculty of Science Division of Chemistry

Professional career (1)：

理学博士 (東京大学)

Work history (21)：

2024/04 - 現在 Chubu University Frontier Research Institute Senior Research Professor / Distinguished Professor
2012/04 - 現在 The University of Tokyo Professor Emeritus
2020/04 - 2024/03 Chubu University Frontier Research Institute Designated Professor
2012/04 - 2023/03 The University of Tokyo Science Interpreter Training Programme, Komaba Organization for Educational Excellence, Visiting Professor
2019/04 - 2020/03 Chubu University Research Institute of Science and Technology Designated Professor

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Awards (6)：

2013/03 - UNESCO-L'Oréal L'Oréal-Unesco Prize for Women in science Elucidating the molecular chirality that widely occur in nature, and contributing to a wide range of applied research including neurodegenerative diseases
2009/04 - Ministry of Education, Culture, Sports, Science and Technology Japan Prizes for Science and Technology, The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology Study on chirality measurement in the solid state
2004 - Foundation for Promotion of Matierial Science and Technology of Japan The Yamazaki Teiichi pりぜ Development of universal chiroptical spectrometers and their application to solid-state samples
2003 - Molecular Chirality Research Organization (MCRO) Molecular Chirality Award Elucidation of the mechanism of chirality geneeation in solid-state reactions and crystallization
1993/05 - Society for a Bright Future for Women Scientists Saruhashi Prize Research on the mechanism for identifying asymmetric left and right molecules and DNA base sequences

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