Rchr
J-GLOBAL ID：200901047461053860
Update date: Nov. 19, 2024
Iwasaki Hiroshi
イワサキ ヒロシ | Iwasaki Hiroshi
Affiliation and department：
Job title：
Professor
Research field (1)：
Molecular biology
Research theme for competitive and other funds (32)：
- 2022 - 2027 Molecular mechanism of DNA repair by homologous recombination
- 2018 - 2022 ATP依存性リコンビナーゼによるDNA鎖交換反応の統合的理解
- 2015 - 2020 Chromosome OS
- 2015 - 2020 Molecular Mechanism of homologous recombination-mediated DNA double strand break repair
- 2015 - 2017 Molecular mechanism of Cryptococcus liquefaciens N6 strain
- 2012 - 2016 Studies on temporospatial regulation of homologous recombination
- 2010 - 2016 Systematic understanding of genome adaptation
- 2010 - 2015 Molecular analysis of mating-type switching in fission yeast.
- 2011 - 2012 Bisexual reproduction in triploid planarians
- 2011 - 2012 Structure-function relationships of Rad51-Swi5-Sfr1 complex for homologous recombination
- 2009 - 2011 Molecular mechanism of genetic DNA rearrangements in fission yeast
- 2005 - 2009 Molecular mechanism of a recovery from stalled replication forks coupled with homologous recombination and its regulation
- 2007 - 2008 Molecular analysis of recombination mediators from fission yeast
- 2006 - 2008 分裂酵母の相同組換えにおけるFbh1ヘリケースの機能解析
- 2004 - 2006 Molecular mechanism of homologous recombinational repair in Schizosaccharomyces pombe
- 2001 - 2006 Molecular Mechanisms of Genome Homeostasis
- 2001 - 2005 Mechanisms of Formation and Resolution of Holliday junction in Recombination and Replication
- 2004 - 2004 分裂酵母の組換え修復機構を形成する遺伝子ネットワークの解析
- 2003 - 2003 分裂酵母のDNA二重鎖切断修復機構を形成する遺伝子ネットワークの解析
- 2002 - 2002 分裂酵母のDNA二重鎖切断修復機構を形成する遺伝子ネットワークの解析
- 2001 - 2001 分裂酵母のDNA二重鎖切断修復機構を形成する遺伝子ネットワークの解析
- 1998 - 2000 Repair Mechanisms of DNA Double Strand Breaks
- 1994 - 1996 Molecular mechanisms of branch migration and resolution of Holliday junctions
- 1995 - 1995 RecG蛋白質による相同組換え中間体ホリデ-構造の分岐点移動反応の分子機構
- 1995 - 1995 大腸菌RuvCエンドヌクレアーゼの構造と機能
- 1994 - 1994 大腸菌の相同組換えに関与する新しい遺伝子recHの解析
- 1994 - 1994 大腸菌RuvCエンドヌクレアーゼの構造と機能
- 1994 - 1994 組換え修復酵素の構造の機能
- 1993 - 1993 相同組換えの中間体解離酵素RuvCエンドヌクレアーゼの解析
- 1993 - 1993 組換え中間体Holliday構造に作用する組換え修復酵素の構造と機能
- 1992 - 1992 組換え中間体“Holliday構造"を切断するエンドヌクレアーゼRuvCの解析
- 1990 - 1992 Molecular Mechanisms of Radiation and Chemical Mutagenesis
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Papers (132)：
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Kentaro Ito, Takahisa Maki, Shuji Kanamaru, Masayuki Takahashi, Hiroshi Iwasaki. The Swi5-Sfr1 complex regulates Dmc1- and Rad51-driven DNA strand exchange proceeding through two distinct three-stranded intermediates by different mechanisms. Nucleic Acids Research. 2024
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Masayuki Takahashi, Kentaro Ito, Hiroshi Iwasaki, Bengt Norden. Linear dichroism reveals the perpendicular orientation of DNA bases in the RecA and Rad51 recombinase filaments: A possible mechanism for the strand exchange reaction. Chirality. 2024. 36. 4. e23664
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Maierdan Palihati, Hiroshi Iwasaki, Hideo Tsubouchi. Analysis of the indispensable RAD51 cofactor BRCA2 in Naganishia liquefaciens, a Basidiomycota yeast. Life science alliance. 2024. 7. 2
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Masayuki Takahashi, Axelle Renodon-Corniere, Tsutomu Mikawa, Naoyuki Kuwabara, Kentaro Ito, Dmitri Levitsky, Hiroshi Iwasaki. Human Rad51 Protein Requires Higher Concentrations of Calcium Ions for D-loop Formation Than for Oligonucleotide Strand Exchange. 2024
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Wei Lee, Hiroshi Iwasaki, Hideo Tsubouchi, Hung-Wen Li. Hop2-Mnd1 and Swi5-Sfr1 stimulate Dmc1 filament assembly using distinct mechanisms. Nucleic acids research. 2023. 51. 16. 8550-8562
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MISC (17)：
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Hiroshi Iwasaki, Kentaro Ito, Yasuhiro Tsutsui, Yumiko Kurokawa, Yasuto Murayama, Masayuki Takahashi. Genetic interactions of Rad51 with Swi5-Sfr1 and with Rad55-Rad57 protein complexes in Schizosaccharomyces pombe. GENES & GENETIC SYSTEMS. 2015. 90. 6. 388-388
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Yasuhiro Tsutsui, Kentaro Itoh, Yumiko Kurokawa, Hiroshi Iwasaki. Regulation of Rad51 recombinase by Fbh1 in fission yeast. GENES & GENETIC SYSTEMS. 2014. 89. 6. 324-324
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Kentaro Ito, Yasuhiro Tsutsui, Kota Mayanagi, Yumiko Kurokawa, Yuichi Kokabu, Mitsunori Ikeguchi, Fumiaki Yamao, Hiroshi Iwasaki. Molecular analysis of the Schizosaccharomyces pombe Rad51 recombinase mutant with a mutation of H315 residue. GENES & GENETIC SYSTEMS. 2012. 87. 6. 436-436
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Yong-Woon Han, Hiroaki Yokota, Takashi Hishida, Hiroshi Iwasaki, Masahito Hayashi, Hideo Shinagawa, Yoshie Harada. Biochemical Analysis of RuvA-RuvB Complex Formation During Branch Migration of Holliday Junction DNA. BIOPHYSICAL JOURNAL. 2010. 98. 3. 65A-65A
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Yumiko Kurokawa, Yasuhiro Tsutsui, Hiroshi Iwasaki, Fumiaki Yamao. Roles of fission yeast F-box helicase in regulation of homologous recombination. GENES & GENETIC SYSTEMS. 2009. 84. 6. 437-437
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Education (2)：
- - 1991 Osaka University Graduate School, Division of Medicine microbiology
- - 1991 Osaka University
Association Membership(s) (3)：
日本蛋白質科学会
, 日本分子生物学会
, 日本遺伝学会
