Rchr
J-GLOBAL ID：200901049241691176   Update date: Dec. 13, 2024

Rikinari HANAYAMA,

ハナヤマ リキナリ | Rikinari HANAYAMA,
Affiliation and department：
Kanazawa University, Professor, WPI Nano Life Science Institute (NanoLSI)

About Kanazawa University, Professor, WPI Nano Life Science Institute (NanoLSI)


Other affiliations (1)：
Homepage URL  (2)： http://immunology.w3.kanazawa-u.ac.jp ,  http://immunology.w3.kanazawa-u.ac.jp/index2.html
Research field  (3)： Medical biochemistry ,  Physiology ,  Immunology
Research keywords  (5)： Exosome ,  Extracellular Vesicle ,  Immunoregulation ,  Neurodegeneration ,  Tumor Progression
Research theme for competitive and other funds  (30)：
  • 2024 - 2029 Development of active targeting methods using designer exosomes
  • 2024 - 2028 Elucidation of bio-regulatory mechanisms by brain-derived exosomes
  • 2024 - 2027 Establishment of mass production and quality control technology for high quality exosome formulations
  • 2023 - 2027 Exosomes derived from intestinal bacteria and their prophylaxis in bronchial asthma caused by chemicals in the environment.
  • 2024 - 2026 Development of designer exosomes that induce cancer antigen-specific cellular immunity
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Papers (61)：
  • Hironori Kawahara, Rikinari Hanayama. Neurodegenerative disorder and fine particululate matter. Extracellular Fine Particles in press. 2024
  • Yifan Li, Kouyuki Hirayasu, Gen Hasegawa, Yosei Tomita, Yuko Hashikawa, Ryosuke Hiwa, Hisashi Arase, Rikinari Hanayama. Fibrinogen induces inflammatory responses via the immune activating receptor LILRA2. Frontiers in Immunology. 2024. 15. 1435236-1435236
  • Kyosuke Yanagawa, Akiko Kuma, Maho Hamasaki, Shunbun Kita, Tadashi Yamamuro, Kohei Nishino, Shuhei Nakamura, Hiroko Omori, Tatsuya Kaminishi, Satoshi Oikawa, et al. The Rubicon-WIPI axis regulates exosome biogenesis during ageing. Nature Cell Biology. 2024. 26. 9. 1558-1570
  • Yoshitaka Zaimoku, Kazuya Sakai, Noriaki Tsuji, Kazuyoshi Hosomichi, Shinya Yamada, Dung Cao Tran, Miku Kobayashi, Ayana Sugiyama, Kouyuki Hirayasu, Hiroki Mizumaki, et al. Haematopoietic regeneration by HLA-A*0206-deficient clones in severe aplastic anaemia without definitive immunosuppressive treatment. British Journal of Haematology. 2024
  • Yoshinobu Takakura, Rikinari Hanayama, Kazunari Akiyoshi, Shiroh Futaki, Kyoko Hida, Takanori Ichiki, Akiko Ishii-Watabe, Masahiko Kuroda, Kazushige Maki, Yasuo Miura, et al. Quality and Safety Considerations for Therapeutic Products Based on Extracellular Vesicles. Pharmaceutical Research. 2024. 41. 8. 1573-1594
ｍore...
MISC (24)：
  • Rikinari Hanayama, Takafumi Seto. Elucidation and Regulation of Biological Responses by Fine Particles. Journal of Japanese Society for Atmospheric Enivronment. 2025. 60. 1
  • Shota Imai, Tomoyoshi Yamano, Rikinari Hanayama. Immunoregulation by extracellular vesicles (Japanese). Journal of Clinical and Experimental Medicine. 2024. 291. 9. 668-672
  • Xiabing Lyu, Tomoyoshi Yamano, Rikinari Hanayama. Exosome-based Nucleic Acid Therapeutics (Japanese). Drug Delivery System. 2024. 39. 5. 346-353
  • Yoshihiro Araki, Hiroyuki Tsuchiya, Rikinari Hanayama. Potential clinical applications of microRNAs derived from osteosarcoma cells. (Japanese). Precision Medicine. 2024. 7. 4. 71-76
  • Kenji Goto, Takeshi Yoshida, Yayoi Inomata, Rikinari Hanayama, Akifumi Seto. Elucidation of biological responses to atmospheric particulates (Japanese). Seikagaku. 2023. 95. 2. 151-156
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Patents (8)：
  • Compounds for promoting the secretion of extracellular vesicles
  • Compositions for regulating CAR-T cell activation, hematopoietic stem cell proliferation, and iPS cell differentiation, and use thereof
  • Immunoregulatory method, nucleic acid for immunoregulation and use thereof 2
  • Immunoregulatory method, nucleic acid for immunoregulation and use thereof 1
  • Antigen-presenting extracellular vesicles
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Books (13)：
  • Extracellular Fine Particles
    Springer 2024
  • Experimental Medicine: Neurodegenerative diseases
    Yodosha 2023
  • Experimental Medicine: New Macrophage
    Yodosha 2022
  • Experimental Medicine: Biology of EVs
    Yodosha 2021
  • Experimental Medicine: New Generation Flow Cytometry
    Yodosha 2021
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Lectures and oral presentations  (126)：
  • Special Lecture, 10th Lung Cancer Bio-conference
    (Tokyo 2025)
  • Senri Life Science Seminar
    (Osaka 2025)
  • Keynote Lecture, The 43rd Annual Meeting of the Japanese Society of Aesthetic Dermatology
    (Osaka 2025)
  • 17th European meeting on glial cells in health and disease
    (Marseille, France 2025)
  • Graduate School Special Lecture, Hamamatsu University School of Medicine
    (Hamamatsu 2025)
ｍore...
Education (3)：
  • 2000 - 2004 Ph.D, Osaka University (Advisor: Prof. Shigekazu Nagata)
  • 1993 - 1999 MD, Osaka University
  • 1990 - 1993 Takatsuki High School
Professional career (1)：
  • MD, PhD (Osaka University)
Work history (12)：
  • 2019 - 現在 Coordinator, WISE Program for Nano-Precision Medicine, Science, and Technology, Kanazawa University
  • 2018 - 現在 JST CREST Investigator
  • 2017 - 現在 Professor, WPI Nano Life Science Institute, Kanazawa University
  • 2015 - 現在 Professor, Department of Immunology, Graduate School of Medical Sciences, Kanazawa University
  • 2015 - 2017 Program Officer, KAKENHI, MEXT
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Committee career (12)：
  • 2023 - 現在 Acting Member, Research Funding Subcommittee, Council for Science and Technology, MEXT
  • 2020 - 現在 JST FOREST Program Director Committee Member
  • 2019 - 現在 Advisor, FUJIFILM Wako
  • 2019 - 現在 Councilor, The Japanese Society for Immunology
  • 2019 - 現在 Councilor, The Japanese Biochemical Society
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Awards (10)：
  • 2021 - JB Reviewer Award
  • 2019 - Kanazawa University Meritorious Award
  • 2014 - Osaka University President's Commendation
  • 2013 - Osaka University President's Award
  • 2012 - Astellas Biomedical Award
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Association Membership(s) (5)：
International Society for Extracellular Vesicles ,  Japanese Society for Extracellular Vesicles ,  The Japanese Society of Drug Delivery System ,  The Japanese Society for Immunology ,  The Japanese Biochemical Society
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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