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J-GLOBAL ID:200901050662129939
Update date: Mar. 27, 2025
takaaki abe
アベ タカアキ | takaaki abe
Affiliation and department:
Tohoku University Graduate School of Biomedical Engineering Department of Biomedical Engineering Regenerative and Biomedical Engineering Medical Science
About Tohoku University Graduate School of Biomedical Engineering Department of Biomedical Engineering Regenerative and Biomedical Engineering Medical Science
2021 - 2024 A novel therapeutic strategy for pancreatic and biliary tract cancer by targeting the intestinal microbiota for anti-tumor immune activation
2021 - 2024 Development of a new renal therapy through Gut-renal axis
2020 - 2023 Drug discovery for Diabetic Nephropathy through altering gut microbiota community
2020 - 2023 The protective effects of new mitochondrial modulators on onset and progression of osteoarthritis
2015 - 2018 Application of new indole compounds to organ protection in the Cardiovascular surgery
2014 - 2017 Relation between 1-metyl adenosinea and rheumatoid arthritis
2014 - 2017 Development of novel drugs for CKD
2014 - 2016 Indole analog mitochonic acid-5 (MA-5) has novel therapeutic effects on kidney injury
2012 - 2015 Functional analysis and clinical application of the Ubiquitin - Proteasome pathway in the process of renal ischemia reperfusion injury.
2011 - 2015 Regulatory mechanism for ion transporters in renal tubules
2012 - 2014 Biomarkers for ischemia and renal faiure
2011 - 2014 Blockade of renal malignant cycle by transcriptional regulation of SLCO transporter
2009 - 2011 Elucidation of the mechanism of perioperative kidney injury and establishment of the new strategy of kidney protection in Cardiovascular surgery.
2009 - 2010 インスリン分泌と有機アニオントランスポーター
2008 - 2010 Development of in vivo evaluation system of human organic anion transpoter
2006 - 2009 Identification of regulatory factors for functional expression of ion channels to clarify the pathogenesis of hypertension
2007 - 2008 有機アニオントランスポーターモデルマウス
2006 - 2008 Neurovascular compression of the rostral ventrolateral medulla related to essential hypertension, MRI study
2006 - 2007 Clinical application of the origanic anion transporter family
2005 - 2007 Function and role for organic anion transporter expressed in gastrointestinal and breast cancer
2004 - 2005 Functional regulation and clinical application of the organic anion transporter LST family.
2003 - 2004 Cardiorenal association
2002 - 2003 胎盤絨毛細胞へのアニオントランスポーター遺伝子導入による胎児治療の試み
2002 - 2003 眼組織における有機アニオントランスポーターの発現と機能の解析
2002 - 2003 Molecular characterization of the organic anion transporter family
2002 - 2003 腸肝循環を担う新規ヒト有機アニオントランスポーター遺伝子の構造と機能の解明
2001 - 2003 A study of novel transporters resposible for Uptake of the anticancer drugs a new strategy to increase the efficacy of anticancer drugs
2001 - 2003 New Frontiers of Bile Acid Research -Act as a Transcriptional factor for Liver and Gastrointestinal cancers-
2001 - 2002 癌細胞膜における薬物輸送システムの解明は新たな化学療法開発に道を開く
2001 - 2002 Possible involvement of PKC anchoring protein in the modulation of voltage-dependent K^+ channels by endothelin
2001 - 2002 Identification of organic anion transporter LST-2 which expressed in the gastrointestinal cancers: clinical implication for anticancer drug delivery.
Yoshiyasu Tongu, Tomoko Kasahara, Yasutoshi Akiyama, Hsin-Jung Ho, Yotaro Matsumoto, Ryota Kujirai, Koichi Kikuchi, Koji Nata, Makoto Kanzaki, Kenshin Suzuki, et al. Hypoglycemia and hyperinsulinemia induced by phenolic uremic toxins in CKD and DKD patients. 2024
Toshihiro Sato, Ayaka Yagi, Minami Yamauchi, Masaki Kumondai, Yu Sato, Masafumi Kikuchi, Masamitsu Maekawa, Hiroaki Yamaguchi, Takaaki Abe, Nariyasu Mano. The Use of an Antioxidant Enables Accurate Evaluation of the Interaction of Curcumin on Organic Anion-Transporting Polypeptides 4C1 by Preventing Auto-Oxidation. International Journal of Molecular Sciences. 2024
鯨井涼太, 安部水輝, 平本航大, 渡辺匠, 鈴木千登世, 豊原敬文, 豊原敬文, 阿部高明, 阿部高明, 松本洋太郎, et al. Development of LC-MS/MS simultaneous quantitative method for biomarker candidate compounds aimed to realize a prognostic method for renal function in diabetic kidney disease. 日本薬学会年会要旨集(Web). 2024. 144th
小川裕美佳, 豊原敬文, 豊原敬文, 松橋徹郎, 及川善嗣, 渡邉駿, 菊地晃一, 鈴木健弘, 鈴木健弘, 呉繁夫, et al. Beneficial Effects of Mitochondrial-homing Drug on Pyruvate Dehydrogenase Complex Deficiency. 日本小児科学会雑誌. 2023. 127. 2