Rchr
J-GLOBAL ID：200901050777382727
Update date: Sep. 11, 2024
Goitsuka Ryo
ゴイツカ リヨウ | Goitsuka Ryo
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
https://www.ribs.tus.ac.jp/index.php/institute/labforres/goitsukalab/
Research field (3)：
Veterinary medicine
, Zoological sciences
, Laboratory animal science
Research keywords (1)：
Immunology, Allergy, Development
Research theme for competitive and other funds (35)：
- 2021 - 2024 Chronological impact of fetal immune memory on visceral adipose tissue inflammation
- 2016 - 2019 Research on spleen microenvironment supporting extramedullary hematopoiesis and its application to the expansion of hematopoietic stem cells
- 2015 - 2017 転写因子によるリプログラミングを軸とした脾臓微小環境形成機構の解明
- 2014 - 2016 Spleen mesenchymal cells incorporated into the pancreatic microenvironment
- 2013 - 2016 Phenotypical and functional characterization of mesenchymal stem cells in the spleen
- 2013 - 2015 免疫・造血ニッチとしての脾臓微小環境の形成ならびに再生の制御機構
- 2012 - 2014 The control mechanism of B cells activation due to pKnox1 homeodomain transcription factor
- 2011 - 2014 Molecular basis of myeloid leukemogenesis
- 2011 - 2013 Meis1 regulates epidermal stem cells and is required for skin tumorigenesis
- 2011 - 2012 Generation of artificial thymus using trans-differentiation potentials between skin and thymic epithelial cells
- 2009 - 2011 Transcription factor network involved in maintenance and regeneration of epithelial progenitor cells in the thymus
- 2009 - 2010 分化抑制解除による肥満細胞性白血病幹細胞の同定とその発生・維持機構の解明
- 2006 - 2007 Pathophysiological roles of basophils and mast cells in allergic inflammations
- 2005 - 2006 NK細胞活性化制御による腫瘍監視の増強
- 2004 - 2004 ナチュラルキラー細胞活性化制御に基づいた腫瘍抵抗性の増強
- 2004 - 2004 NK細胞活性化制御による腫瘍監視の増強
- 2002 - 2004 Corss-talk of signals between immunoreceptors and cytokine receptors for development of allergy
- 2000 - 2002 Anti-allergic therapy targeting to a mast cell-specific signaling protein
- 2001 - 2001 高頻度で相同組換えを起こすB細胞株を用いた多重遺伝子ファミリーの機能解析
- 1999 - 2001 Regulation of development of type I allergy by the signal transducer specific for the high-affinity IgE receptor
- 1998 - 2000 アレルギー炎症における好塩基球と肥満細胞の病態生理学的役割の解明
- 1998 - 2000 Pathophysiological roles of basophils and mast cells in allergic reactions
- 1998 - 1999 Notch関連分子によるニワトリ造血幹細胞自己復製制御機構
- 1996 - 1998 Development of molecular probes for genome-wide genotyping by restriction landmark genomic scanning (RLGS) method.
- 1992 - 1993 Clinical pathobiological studies on Sarcocystosis
- 1992 - 1993 Aberration of oncogenes and tumor suppressor genes in hematopocetic tumors in animals
- 1991 - 1993 Studies on the mechanisms of persistent infection and reactivation of animal viruses
- 1992 - 1992 ニワトリの免疫グロブリン抗原レセプター複合体を形成する分子の遺伝子クローニング
- 1991 - 1991 家畜の好酸球増多症におけるインターロイキン5の動態に関する研究
- 1990 - 1991 Basic and Clinical Studies on abnormal expression of cytokine receptors in animals
- 1990 - 1991 Clinico-Pathological Studies on Canine Babesiosis
- 1990 - 1990 ネコのインターロイキン2(1L-2)レセプターに関する研究
- 1989 - 1989 ウシおよびネコの白血病細胞の産生するサイトカインに関する研究
- 1988 - 1989 Basic and clinical studies on the immunopathogenesis of viral infection
- 1988 - 1989 Studies on canine erythrocyte insulin receptors
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Papers (70)：
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Keiko Fujisaki, Shogo Okazaki, Shuhei Ogawa, Miyama Takeda, Eiji Sugihara, Kenichi Imai, Seiya Mizuno, Satoru Takahashi, Ryo Goitsuka. B Cells of Early-life Origin Defined by RAG2-based Lymphoid Cell Tracking under Native Hematopoietic Conditions. Journal of immunology (Baltimore, Md. : 1950). 2024. 213. 1-10
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Atsuya Sawabe, Shogo Okazaki, Akira Nakamura, Ryo Goitsuka, Tomonori Kaifu. The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor. Journal of leukocyte biology. 2024
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Yuki Kugii, Yui Kuroki, Yasushi Hara, Ryo Goitsuka, Naoko Nakano. Lack of Herpes Virus Entry Mediator Signals in Thymocytes Impairs Conventional CD8 T Cell Selection and Promotes Memory-like CD8 T Cell Development. The Journal of Immunology. 2023
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Akihisa Oda, Shoko Furukawa, Masahiro Kitabatake, Noriko Ouji-Sageshima, Shota Sonobe, Kaoru Horiuchi, Yuto Nakajima, Kenichi Ogiwara, Ryo Goitsuka, Midori Shima, et al. The spleen is the major site for the development and expansion of inhibitor producing-cells in hemophilia A mice upon FVIII infusion developing high-titer inhibitor. Thrombosis research. 2023. 231. 144-151
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Yotaroh Sato, Miho Tsuyusaki, Hiromi Takahashi-Iwanaga, Rena Fujisawa, Atsushi Masamune, Shin Hamada, Ryotaro Matsumoto, Yu Tanaka, Yoichi Kakuta, Yumi Yamaguchi-Kabata, et al. Loss of CAPS2/Cadps2 leads to exocrine pancreatic cell injury and intracellular accumulation of secretory granules in mice. Frontiers in molecular biosciences. 2022. 9. 1040237-1040237
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MISC (30)：
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小田朗永, 後飯塚僚. 成体脾臓における髄外造血ニッチとその構成要素. 医学のあゆみ. 2018. 264. 3. 258-259
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鯉沼 真吾, 野村 理子, 小島 拓哉, 根岸 亮太, 竹内 公平, 瀬木 恵里, 田, 後飯塚 僚, 古市 貞一, 岩倉 洋一郎, et al. 膜輸送を介して突起伸展を促進するRhoファミリーGタンパク質TC10は末梢神経の軸索再生に働く. 生命科学系学会合同年次大会. 2017. 2017. 1205-1206
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Y. Tashiro, A. Murakami, T. Shimizu, R. Goitsuka, H. Kishimoto, T. Azuma. High-affinity IgM(+) memory B cells are deficient in terminal differentiation potential to secrete IgM antibodies by restimulation with (4-hydroxy-3-nitrophenyl) acetyl-chicken gamma-globulin. EUROPEAN JOURNAL OF IMMUNOLOGY. 2016. 46. 1147-1147
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後飯塚僚. 間葉系ストローマ細胞による造血制御とその応用. 家畜感染症学会誌. 2016. 5. 2. 69-74
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奥村 和弘, 佐藤 美穂, 斎藤 慈, 大澤 光次郎, 岩間 厚志, 廣瀬 哲史, 木南 凌, 後飯塚 僚, 中村 卓郎, 若林 雄一. Meis 1遺伝子の皮膚化学発がんにおける機能を明らかにする(Targeted disruption of Meis1 demonstrated a role for epidermal stem cells in skin carcinogenesis). 日本癌学会総会記事. 2012. 71回. 246-246
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Patents (2)：
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観察方法、測定方法、解析方法、定量方法、およびキット
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観察方法、測定方法、解析方法、定量方法、およびキット
Books (4)：
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獣医臨床のための免疫学
学窓社 2016 ISBN:9784873627533
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アレルギー疾患イラストレイテッド 第2版
メディカルレビュー社 2010
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BASH/SLAP-76ファミリーアダプター分子MISTによる免疫細胞機能制御
中外医学社 「Annual Review 免疫 2003」 2003
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アダプター分子MISTによる免疫細胞機能の制御
中山書店 「免疫 2003」 2003
Lectures and oral presentations (111)：
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The origin of natural IgM-producing cells assessed by the RAG2-based cell fate tracking system.
(第52回日本免疫学会学術集会 2024)
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Composition of the adult B-1 cell pool revealed by a novel RAG2 lineage tracing system.
(18th International Congress of Immunology 2023)
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時期特異的リンパ球系譜追跡システムを用いた成体B-1細胞プールの解析
(第32回学術集会Kyoto T Cell Conference 2023)
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Two distinct subsets of embryo-derived B cells in adulthood.
(第51回日本免疫学会学術集会 2022)
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Embryo-derived innate-like B cells expressing the J-chain in cardiac fat-associated lymphoid clusters.
(第51回日本免疫学会学術集会 2022)
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Professional career (1)：
- Ph.D. (The University of Tokyo)
Work history (5)：
- 2007/04 - Division of Development and Aging, Research Institute for Biological Sciences, Tokyo University of Sciences Professor
- 2006 - 2007 Division of Development and Aging, Research Institute for Biological Sciences, Tokyo University of Sciences Associate Professor
- 1997 - 2006 Division of Molecular biology, Research Institute for Biological Sciences, Tokyo University of Sciences Associate Professor
- 1995 - 1998 Japan Science and Technology Coorporation, Researcher
- 1987 - 1995 The University of Tokyo, Research Assistant
Committee career (19)：
- 2022/04/01 - 2024/03/31 日本獣医学会 評議委員
- 2021/04/01 - 2023/03/31 Kyoto T cell Conference 運営委員
- 2020/04/01 - 2022/03/31 日本獣医学会 評議委員
- 2019/04/01 - 2021/03/31 Kyoto T cell Conference 運営委員
- 2018/04/01 - 2020/03/31 日本獣医学会 評議委員
- 2018/04/01 - 2019/03/31 Kyoto T cell Conference 運営委員
- 2017/04/01 - 2018/03/31 Kyoto T cell Conference 運営委員
- 2016/04/01 - 2018/03/31 日本獣医学会 評議委員
- 2014/04/01 - 2016/03/31 日本獣医学会 評議委員
- 2011/04/01 - 2013/03/31 日本獣医学会 評議委員
- 2008/04/01 - 2010/03/31 日本獣医学会 評議委員
- 2006/04/01 - 2008/03/31 Discussion Committee
- 2006/04/01 - 2008/03/31 Discussion Committee
- 2004/04/01 - 2006/03/31 Disucussion Committee
- 2004/04/01 - 2006/03/31 Disucussion Committee
- 2002/04 - 2004/03 DIscussion Committee
- 2002/04 - 2004/03 DIscussion Committee
- 2000/04/01 - 2002/03/31 Discussion Committee
- 2000/04/01 - 2002/03/31 Discussion Committee
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Awards (1)：
- 2010/10/29 - 科学研究費補助金第一段審査委員表彰
Association Membership(s) (2)：
日本獣医学会
, Kyoto T cell Conference
