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J-GLOBAL ID：200901051469741623   Update date: Feb. 11, 2025

Saitoh Hiroshi

サイトウ ヒロシ | Saitoh Hiroshi
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Affiliation and department：
Health Sciences University of Hokkaido Faculty of Pharmaceutical Sciences Department of Pharmaceutics

About Health Sciences University of Hokkaido Faculty of Pharmaceutical Sciences Department of Pharmaceutics


Research field  (2)： Pharmacology ,  Pharmaceuticals - chemistry and drug development
Research keywords  (2)： 薬物の消化管吸収 ,  Drug Absorption
Research theme for competitive and other funds  (4)：
  • 構造修飾による薬物の吸収性の改善
  • 薬物の難吸収性に関与する消化管吸収抑制機構の解明
  • Study on the method to improve intestinal absorption by structural modification
  • Study on the mechanism which restrict drug absorption
Papers (40)：
  • Yuichi Ichimura, Natsumi Kudoh, Takashi Murabe, Takumi Akao, Sho Watanuki, Takanao Suzuki, Toshihide Saito, Masako Oda, Hiroshi Saitoh. Inhibitory effects of indoxyl sulfate and creatinine on the renal transport of meropenem and biapenem in rats. Drug Metabolism and Pharmacokinetics. 2021. 40. 100406-100406
  • Fuyo Takeda, Masako Oda, Masaru Terasaki, Atsuhito Kubota, Keita Asada, Yuichi Ichimura, Hiroyuki Kojima, Hiroshi Saitoh. Downregulated expression of organic anion transporting polypeptide (Oatp) 2b1 in the small intestine of rats with acute kidney injury. Drug Metabolism and Pharmacokinetics. 2021. 40. 100411-100411
  • Fuyo Takeda, Masako Oda, Masaru Terasaki, Yuichi Ichimura, Hiroyuki Kojima, Hiroshi Saitoh. Downregulated expression of intestinal P-glycoprotein in rats with cisplatin-induced acute kidney injury causes amplification of its transport capacity to maintain “gatekeeper” function. Toxicology and Applied Pharmacology. 2021. 423. 115570-115570
  • Shintarou Takayama, Masako Oda, Hiroshi Saitoh. Investigation of leftover hyperphosphatemia drugs in hemodialysis outpatients. Yakugaku Zasshi. 2021. 141. 3. 433-440
  • Makoto Takahashi, Sintarou Takayama, Hideyuki Suga, Shota Kadomura, Masakazu Kojima, Kazunari Iwao, Kiyotaka Takeda, Hideki Sato, Michiya Kobayashi, Hiroshi Saitoh. Factors Resulting Correlation and Differences in Renal Function Evaluation Index Using the Serum Cystatin C and Creatinine as Measured by an Enzymatic Method. YAKUGAKU ZASSHI. 2020. 140. 1. 81-90
ｍore...
MISC (79)：
  • Masako Oda, Yuuki Sekine, Akira Nakayama, Michiya Kobayashi, Hiroshi Saitoh. MODULATION OF THE INTESTINAL ABSORPTION OF ACEBUTOLOL, A P-GLYCOPROTEIN SUBSTRATE, BY ITS REPEATED PARENTERAL ADMINISTRATION TO SPONTANEOUSLY HYPERTENSIVE RATS. DRUG METABOLISM REVIEWS. 2008. 40. 221-221
  • Hiroshi Saitoh, Reiko Shigetaka, Masako Oda, Michiya Kobayashi. POTENT BILIARY EXCRETION OF INTRAVENOUSLY ADMINISTERED GLUCURONIDES IN RATS. DRUG METABOLISM REVIEWS. 2008. 40. 216-217
  • 岩尾 一生, カワイ トキエ ルシアナ, 小田 雅子, 中山 章, 小林 道也, 齊藤 浩司, 遠藤 泰. 30-P3-71 糖尿病用薬と種々健康食品の物理化学的相互作用に関する検討(相互作用,社会の期待に応える医療薬学を). 日本医療薬学会年会講演要旨集. 2007. 17. 369-369
  • 高橋 健太, 坂上 麻美, 関沢 祐一, 大江 利治, 西川 鑑, 荒木 鷹広, 小田 雅子, 小林 道也, 齊藤 浩司. 01P2-156 P-糖タンパク基質薬物の体内動態 : 性周期関連ホルモンの影響(薬物動態(TDM・投与設計等),医療薬学の扉は開かれた). 日本医療薬学会年会講演要旨集. 2006. 16. 554-554
  • 竹内 淳子, 小林 道也, 小田 雅子, 齋藤 浩司, 五十君 篤哉, 尾下 公人. ヒト幹細胞移植に対して免疫抑制剤のモニタリングを行った2症例. TDM研究. 2005. 22. 3. 236-237
ｍore...
Professional career (1)：
  • Ph.D.
Association Membership(s) (5)：
日本TDM学会 ,  American Association of Pharmaceutica Scientists ,  日本薬剤学会 ,  日本薬物動態学会 ,  日本薬学会
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