Rchr
J-GLOBAL ID：200901052884708344   Update date: Aug. 08, 2024

Ueno Yoshihito

ウエノ ヨシヒト | Ueno Yoshihito
Affiliation and department：
Gifu University Faculty of Applied Biological Sciences Molecular Life Science,The Food and Life Science program

About Gifu University Faculty of Applied Biological Sciences Molecular Life Science,The Food and Life Science program


Job title： Professor
Other affiliations (4)：
  • Gifu University
  • Gifu University  The United Graduate School of Agricultural Science 
  • Gifu University
  • 東海国立大学機構  One Medicine 創薬シーズ開発・育成研究教育拠点   教授
Homepage URL  (2)： http://www1.gifu-u.ac.jp/~biochem/ ,  http://www1.gifu-u.ac.jp/%7Ebiochem/
Research field  (3)： Molecular biochemistry ,  Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - chemistry and drug development
Research keywords  (14)： Organic Chemistry of Nucleic Acids ,  核酸有機化学 ,  miRNA ,  RNAi ,  ヌクレオチド ,  RNA ,  ヌクレオシド ,  核酸医薬 ,  核酸 ,  アンチセンス ,  siRNA ,  オリゴヌクレオチド ,  遺伝子 ,  DNA
Research theme for competitive and other funds  (22)：
  • 2020 - 2024 Basic study on essential understanding and innovative application of the lipid metabolism improvement peptide derived from food protein
  • 2017 - 2020 Fundamental study on the lipid lowering peptides derived from food proteins
  • 2014 - 2017 Discovery of Innovative lipid lowering peptides by targetting the bio-molecule and Creation of novel screening technology
  • 2016 - 2017 組織特異的送達能を有するコンジュゲートsiRNAの創成
  • 2013 - 2016 Development of the tumor marker detection method by RNA aptamer
Show all
Papers (180)：
  • Hitotaka Sato, Akash Chandela, Yoshihito Ueno. Synthesis and characterization of novel (S)-5'-C-aminopropyl-2'-fluorouridine modified oligonucleotides as therapeutic siRNAs. Bioorganic & medicinal chemistry. 2023. 87. 117317-117317
  • Yujun Zhou, Shuichi Sakamoto, Yoshihito Ueno. Antisense Gapmers with LNA-Wings and (S)-5'-C-Aminopropyl-2'-arabinofluoro-nucleosides Could Efficiently Suppress the Expression of KNTC2. Molecules (Basel, Switzerland). 2022. 27. 21
  • Akash Chandela, Hiroki Ueda, Yoshihito Ueno. Synthesis of 4′- C -(Aminoethyl)thymidine and 4′- C -[( N -Methyl)aminoethyl] Thymidine Nucleosides to Enhance DNA Stability. Current Protocols. 2022. 2. 9. e501
  • Yuki Katsuzaki, Ryo Tsukimura, Akash Chandela, Tokuhiro Chano, Yoshihito Ueno. 4′- <i>C</i> -Aminoethoxy-Modified DNAs Exhibit Increased Nuclease Resistance, Sustained RNase H Activity, and Inhibition of <i>KRAS</i> Gene Expression. Chemistry & Biodiversity. 2022. 19. 8. e202200125
  • Ryutaro Yoshikawa, Atsushi Maeda, Yoshihito Ueno, Hiroki Sakai, Shintaro Kimura, Tomohiro Sawadaishi, Satoru Kohgo, Kohei Yamada, Takashi Mori. Intraperitoneal administration of synthetic microRNA-214 elicits tumor suppression in an intraperitoneal dissemination mouse model of canine hemangiosarcoma. Veterinary research communications. 2022. 46. 2. 447-457
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MISC (55)：
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Patents (19)：
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Books (5)：
  • 人工核酸によるアンチジーン法への展開 三重らせん形成による遺伝子治療
    2003
  • ポリアミン修飾オリゴヌクレオチドの合成とアンチセンス, アンチジーン分子としての性質
    2003
  • Development of new radical reactions with a vinylsilyl group and their application to the synthesis of branched-chain sugar nucleosides
    2002
  • Development of new radical reactions with a vinylsilyl group and their application to the synthesis of branched-chain sugar nucleosides
    Recent Advances in Nucleosides:Chemistry and Chemotherapy 2002
  • ヌクレオペプチドの化学合成
    1995
Education (2)：
  • 1987 - 1992 東京工業大学大学院 総合理工学研究科 生命化学専攻
  • 1983 - 1987 Tokyo University of Science
Professional career (3)：
  • (BLANK) (Tokyo Institute of Technology)
  • 修士(理学) (東京工業大学)
  • 学士(理学) (東京理科大学)
Work history (5)：
  • 2013/04 - 現在 Gifu University
  • 2011/04 - 2013/03 Gifu University
  • 2001/04 - 2011/03 Gifu University Faculty of Engineering, Department of Biomolecular Science
  • 1993/06 - 2001/03 Hokkaido University Faculty of Pharmaceutical Sciences
  • 1992/04 - 1993/05 科学技術庁 (理化学研究所) 基礎科学特別研究員
Committee career (1)：
  • 2015/04 - 現在 日本核酸医薬学会 評議員
Association Membership(s) (4)：
日本核酸化学会 ,  日本核酸医薬学会 ,  日本農芸化学会 ,  日本化学会
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