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J-GLOBAL ID：200901053012751278
Update date: Mar. 12, 2025 Takahashi Fumi
Takahashi Fumi
- 2017 - 2020 臨床応用に向けたGSK-3活性化物質DIFの抗がん作用標的分子の同定
- 2013 - 2016 G1期阻害物質DIFの抗腫瘍薬としての臨床応用に向けた橋渡し研究
- 2010 - 2012 研究課題:細胞性粘菌由来分化誘導因DIFを用いたmPGES-1発現制御機構の解明
- 2009 - 2012 細胞性粘菌由来G1期阻害物質DIFの抗腫瘍薬としての臨床応用に向けた検討
- 2004 - 2007 微生物由来細胞分化誘導因子によるサイクリンD1分解機構の解明
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- Masaki Arioka, Wang Yi, Kazunobu Igawa, Shin Ishikane, Fumi Takahashi-Yanaga. Differentiation-inducing factor-1 inhibits EMT by proteasomal degradation of TAZ and YAP in cervical and colon cancer cell lines. European journal of pharmacology. 2024. 177184-177184
- Masaki Arioka, Koichi Miura, Ruzhe Han, Kazunobu Igawa, Fumi Takahashi-Yanaga, Toshiyuki Sasaguri. Mammalian target of differentiation-inducing factor-1 is mitochondrial malate dehydrogenase for activation of AMP-activated protein kinase and induction of mitochondrial fission. Life Sciences. 2024. 351. 122807-122807
- Takehiro Kishigami, Shin Ishikane, Masaki Arioka, Kazunobu Igawa, Yosuke Nishimura, Fumi Takahashi-Yanaga. 2,5-Dimethyl-celecoxib induces early termination of inflammatory responses by transient macrophage accumulation and inhibits the progression of cardiac remodeling in a mouse model of cryoinjury-induced myocardial infarction. Journal of Pharmacological Sciences. 2024. 154. 2. 97-107
- Masaki Arioka, Fumi Seto-Tetsuo, Takeru Inoue, Koichi Miura, Shin Ishikane, Kazunobu Igawa, Katsuhiko Tomooka, Fumi Takahashi-Yanaga, Toshiyuki Sasaguri. Differentiation-inducing factor-1 reduces lipopolysaccharide-induced vascular cell adhesion molecule-1 by suppressing mTORC1-S6K signaling in vascular endothelial cells. Life sciences. 2023. 335. 122278-122278
- Shin Ishikane, Masaki Arioka, Fumi Takahashi-Yanaga. Promising small molecule anti-fibrotic agents: Newly developed or repositioned drugs targeting myofibroblast transdifferentiation. Biochemical pharmacology. 2023. 214. 115663-115663
- Masaki Arioka, Fumi Takahashi-Yanaga, Masanori Sasaki, Tatsuya Yoshihara, Sachio Morimoto, Masato Hirata, Yoshihide Mori, Toshiyuki Sasaguri. Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis (vol 90, pg 397, 2014). BIOCHEMICAL PHARMACOLOGY. 2014. 91. 4. 552-553
- Ai Fujita, Fumi Takahashi, Sachio Morimoto, Toshiyuki Sasaguri. Celecoxib and 2,5-dimethyl-celecoxib inhibit cardiac hypertrophy induced by transverse aortic constriction in mice. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 157P-157P
- Tatsuya Yoshihara, Fumie Shiraishi, Hisatomi Arima, Fumi Takahashi-Yanaga, Hideyuki Ikematsu, Toshiyuki Sasaguri. Influence of ALDH2 genotype on vascular endothelial function after a long-term treatment with glyceryl trinitrate. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 133P-133P
- Masaki Arioka, Fumi Takahashi, Masanori Sasaki, Toshiyuki Sasaguri. Acceleration of bone regeneration by topical application of GSK-3 inhibitor. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 95P-95P
- Fumi Takahashi-Yanaga. Activator or inhibitor? GSK-3 as a new drug target. Biochemical Pharmacology. 2013. 86. 2. 191-199
- (BLANK) (Kyushu University)
- 2017/04 - 現在 University of Occupational and Environmental Health, Japan School of Medicine
- 2011/10 - 2017/03 九州大学大学院 医学研究院 講師
- 2007/04 - 2011/09 九州大学大学院 医学研究院臨床薬理学分野 助教
- 1995/03 - 2007/03 Kyushu University
- 1992 - 1995 University of Oxford
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