Aoki Shunji

Research field (1)： Molecular biochemistry

Research keywords (2)：天然薬物学 , Biological Organic Chemistry

Research theme for competitive and other funds (2)：

Papers (24)：

Dexin Kong, Shunji Aoki, Yoshihiro Sowa, Toshiyuki Sakai, Motomasa Kobayashi. Smenospongine, a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leukemia cells. Marine Drugs. 2008. 6. 3. 480-488
Naoyuki Kotoku, Atsushi Hiramatsu, Hiroaki Tsujita, Yoichi Hirakawa, Mami Sanagawa, Shunji Aoki, Motomasa Kobayashi. Structure-activity relationships study of bastadin 6, an anti-angiogenic brominated-tyrosine derived metabolite from marine sponge. ARCHIV DER PHARMAZIE. 2008. 341. 9. 568-577
Shunji Aoki, Yasuo Watanabe, Daiki Tanabe, Masayoshi Arai, Hideaki Suna, Katsushiro Miyamoto, Hiroshi Tsujibo, Kazutake Tsujikawa, Hiroshi Yamamoto, Motomasa Kobayashi. Structure-activity relationship and biological property of cortistatins, anti-angiogenic spongean steroidal alkaloids. Bioorganic and Medicinal Chemistry. 2007. 15. 21. 6758-6762
Taka-Aki Matsui, Yoshihiro Sowa, Hiroaki Murata, Koichi Takagi, Ryoko Nakanishi, Shunji Aoki, Masayuki Yoshikawa, Motomasa Kobayashi, Tomoya Sakabe, Toshikazu Kubo, et al. The plant alkaloid cryptolepine induces p21WAF1/CIP1 and cell cycle arrest in a human osteosarcoma cell line. International Journal of Oncology. 2007. 31. 4. 915-922
Hideaki Suna, Shunji Aoki, Andi Setiawan, Motomasa Kobayashi. Crambescidin 800, a pentacyclic guanidine alkaloid, protects a mouse hippocampal cell line against glutamate-induced oxidative stress. Journal of Natural Medicines. 2007. 61. 3. 288-295

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MISC (39)：

Yasuo Watanabe, Shunji Aoki, Daiki Tanabe, Andi Setiawan, Motomasa Kobayashi. Cortistatins E, F, G, and H, four novel steroidal alkaloids from marine sponge Corticium simplex. TETRAHEDRON. 2007. 63. 19. 4074-4079
Shunji Aoki, Seok Hwan Cho, Mayumi Ono, Takashi Kuwano, Shintaro Nakao, Michihiko Kuwano, Shinsaku Nakagawa, Jian Qing Gao, Tadanori Mayumi, Masabumi Shibuya, et al. Bastadin 6, a spongean brominated tyrosine derivative, inhibits tumor angiogenesis by inducing selective apoptosis to endothelial cells. Anti-Cancer Drugs. 2006. 17. 269-278
T Noguchi, XQ Ren, S Aoki, Y Igarashi, XF Che, Y Nakajima, H Takahashi, R Mitsuo, K Tsujikawa, T Sumizawa, et al. MRP1 mutated in the L-0 region transports SN-38 but not leukotriene C-4 or estradiol-17 (beta-D-glucuronate). BIOCHEMICAL PHARMACOLOGY. 2005. 70. 7. 1056-1065
H Wei, T Itoh, M Kinoshita, N Kotoku, S Aoki, M Kobayashi. Shimalactone A, a novel polyketide, from marine-derived fungus Emericella variecolor GF10. TETRAHEDRON. 2005. 61. 33. 8054-8058
N Kotoku, LW Cao, S Aoki, M Kobayashi. Absolute stereo-structure of kendarimide a, a novel MDR modulator, from a marine sponge. HETEROCYCLES. 2005. 65. 3. 563-578

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Works (2)：

Professional career (2)：

Association Membership(s) (4)：

ÇTMÇÒïTMéqïWìIé°ó√å§ãÜâÔÅ , 日本生薬学会 , 日本癌学会 , 日本薬学会

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