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J-GLOBAL ID：200901056970364270 Update date: Mar. 03, 2025

Arima Yasushi

アリマヤスシ | Arima Yasushi

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Affiliation and department：
Job title： Professor

Research field (3)： Applied molecular and cellular biology , Tumor biology , Anatomy

Research keywords (6)： inflammation and carcinogensis , Taurine , 細胞組織学微細形態 , 免疫組織細胞化学 , Cellular Histological Micromorphology , Immunocytochemistry

Research theme for competitive and other funds (20)：

2022 - 2027 Molecular mechanism and chemoprevention of cholangiocarcinoma induced by liver flukes in Thailand and China
2023 - 2026 放射線損傷をタウリンが緩和するシグナル伝達経路解明とがん治療有害事象緩和への応用
2022 - 2025 Mechanism of action of cancer chemopreventive agents and its application to neurodegenerative diseases: Focus on inflammation
2020 - 2023 放射線による細胞損傷をタウリンが緩和するシグナル伝達経路の解明
2019 - 2023 Mechanism of epigenetic aberration in inflammation-related carcinogenesis: molecular epidemiology by a comparison of risk factors between Japan and China

2019 - 2022 Roles of DAMP and autophagy in inflammation-related carcinogenesis and its application to cancer prevention

2019 - 2021 Can a dietary factor taurine suppress carcinogenesis?

2017 - 2020 A comparative molecular epidemiology study of carcinogenicity on the liver flube infection in the Xijiang (China) and Mekong river (Thailand)

2017 - 2020 Cancer-prevention by aspirin and the mechanism, from the viewpoint of inflammation-related DNA damage and cancer stem cell

2016 - 2019 Establishment of early diagnostic markers for nasopharyngeal carcinoma and experimental verification through fieldwork in southern China

2015 - 2018 Development of minimal-invasive and quantitative analytical method for nitrated DNA damage, and its application to risk assessment of inflammation-related carcinogenesis

2014 - 2017 Cancer risk assessment based on oxidative and nitrative DNA damage in murine lung exposed to Asian sand dust

2013 - 2016 Development of screening methods for early detection of nasopharyngeal carcinoma in southern China

2010 - 2012 A molecular epidemiological study to explore arsenic relation carcinogenesis and malignant progression in an arsenic endemic rural region in Shanxi province of China

2010 - 2012 Molecular epidemiology of nasopharyngeal carcinoma in southern Chinaand searching for early detection biomarkers

2009 - 2011 Cancer prevention study on the relationship of cancer stem cells biomarker and 8-nitroguanine in cancer tissues

2009 - 2011 Molecular epidemiological study on cholangio-carcinogenesis induced by liver fluke Opisthorchis viverrini in Thailand.

2007 - 2009 Molecular epidemiology study on carcinogenic mechanism of Epstein-Barr-associated nasopharyngeal carcinoma and modification by environmental factors in southern China

2006 - 2008 Molecular epidemiological study for bladder carcinogenesis induced by parasite in Egypt

1997 - 1998 虚血網膜における神経伝達物質の変化の検討:免疫組織化学法および免疫電子顕微鏡的研究

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Papers (159)：

Takaichi Miwa, Masaya Sato, Ning Ma, Masahiro Terasawa, Koji Suzuki. Rhamnan Sulfate from the Seaweed Monostroma nitidum May Improve Cognitive Impairment Caused by Hyperglycemia. 2025
Waleeporn Kaewlert, Chadamas Sakonsinsiri, Worachart Lert-Itthiporn, Panupong Mahalapbutr, Saba Ali, Thanyada Rungrotmongkol, Apinya Jusakul, Napat Armartmuntree, Chawalit Pairojkul, Guofei Feng, et al. Buparlisib and ponatinib inhibit aggressiveness of cholangiocarcinoma cells via suppression of IRS1-related pathway by targeting oxidative stress resistance. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024. 180. 117569-117569
Guifeng Wang, Keiichi Hiramoto, Ning Ma, Shiho Ohnishi, Akihiro Morita, Yifei Xu, Nobuji Yoshikawa, Yasuo Chinzei, Mariko Murata, Shosuke Kawanishi. Immunohistochemical analyses reveal FoxP3 expressions in spleen and colorectal cancer in mice treated with AOM/DSS, and their suppression by glycyrrhizin. PLOS ONE. 2024. 19. 8. e0307038-e0307038
Sharif Ahmed, Ning Ma, Jun Kawanokuchi, Keiya Matsuoka, Shinji Oikawa, Hatasu Kobayashi, Yusuke Hiraku, Mariko Murata. Taurine reduces microglia activation in the brain of aged senescence-accelerated mice by increasing the level of TREM2. Scientific reports. 2024. 14. 1. 7427-7427
Atsuo Fujito, Shota Tanaka, Keiichi Hiramoto, Ning Ma, Kazuya Ooi. The Mechanism of 5-Fluorouracil-Induced Hyperpigmentation in HRM-2 Hairless Mice: Focus on the Increase of Blood Vessels. Biological & pharmaceutical bulletin. 2024. 47. 1. 311-317

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MISC (228)：

川ノ口潤, 山下剛範, 松岡慶弥, 有馬寧. LPS誘導炎症モデルマウスにおけるタウリン・鍼刺激によるミクログリア抑制効果. タウリンリサーチ. 2024. 10. 1. 13-16
山下剛範, 加藤俊宏, 川ノ口潤, 伊藤崇志, 具然和, 有馬寧. タウリンによる放射線誘発性肺障害緩和の可能性. タウリンリサーチ. 2024. 10. 1. 20-23
岡野元彦, 何峰, 有馬寧, 小林果, 及川伸二, 西村廣明, 俵功, 村田真理子. タウリンによるヒト上咽頭癌細胞死へのp53およびBeclin 1の関与. タウリンリサーチ. 2024. 10. 1. 17-19
王桂鳳, 平本恵一, 有馬寧, 大西志保, 森田明宏, 徐軼菲, 吉川展司, 村田真理子, 鎮西康雄, 川西正祐. グリチルリチンは脾臓Tregおよび癌のFoxP3発現を減少させることにより、AOM/DSS処置マウスの大腸癌を抑制する(Glycyrrhizin inhibits colon cancer in AOM/DSS-treated mice by decreasing splenic Treg and cancerous FoxP3 expression). 日本癌学会総会記事. 2024. 83回. P-2049
山下剛範, 加藤俊宏, 具然和, 有馬寧. タウリン欠乏が放射線誘導性細胞損傷を引き起こす分子機構の解明. JART: 日本診療放射線技師会誌. 2023. 70. 10. 1155-1155

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Books (4)：

Arsenic
Nova Science Publishers, Inc. New York 2014
IMAGING ANATOMY
2014 ISBN:9784860034443
BIOMARKER
INTECH 2012
Taurine 5: Beginning the 21st Century
Kluwer Academic Plenum Publishers, New York 2003

Education (2)：

1990 - 1994 Mie University Graduate School of Medicine Anatomy and Histology
1979 - 1984 蘇州大学医学部医学部医学

Professional career (1)：

Ph. D (Mie University)

Work history (9)：

2020/04 - 現在鈴鹿医療科学大学・東洋医学研究所・所長
2008/04 - 現在 Suzuka University of Medical Science Faculty of Health Science Professor
2007/04 - 2008/03 Tokushima University Graduate School of Medical Science Department of Anatomy associate professor
1994/04 - 2007/03 Mie University Graduate School, Faculty of Medicine The Second Department of Anatomy Assistant
1989 - 1990 Mie University School of Medicine, research student

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Committee career (1)：

2012/04 - 現在 Taurine Research Executive Director

Awards (3)：

2021/03 - 鈴鹿医療科学大学学生授業評価高得点賞
2013/02 - 鈴鹿医療科学大学教育改善提案優秀賞
2007/03 - 徳島大学医学部ベストティーチャーオブザイヤー2008

Association Membership(s) (3)：

Japanese Journal of Taurine Research , The Japan China Medical Association , 日本癌学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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