Rchr
J-GLOBAL ID:200901058541934282
Update date: Sep. 28, 2024
Kobayashi Junya
コバヤシ ジュンヤ | Kobayashi Junya
Affiliation and department:
Job title:
Professor
Research field (4):
Cell biology
, Molecular biology
, Environmental effects of chemicals
, Environmental effects of radiation
Research keywords (5):
neurodegeneration
, oxidative stress
, Molecular Biology
, Cell Biology
, Radiation Biology
Research theme for competitive and other funds (20):
- 2022 - 2025 放射線増感と防護効果を兼ね備えたクルクミンアナログー新たな化学放射線療法の可能性
- 2020 - 2023 Functional Interaction between MRE11 and ATM in cytoplasmic stress responses
- 2018 - 2020 Effect of space radiation to vascular endothelial cell thorough micronuclei formation
- 2015 - 2019 A Novel Variation of Bacterial Peptidoglycan by New Acetylating Enzyme and Development of Caries Prevention
- 2015 - 2018 Regulation of radiation-induced DNA damage repair through chromatin remodeling
- 2014 - 2018 Role of NBS1 C-terminal domain in genomic stability
- 2014 - 2017 genome stability in germ-line stem cells to irradiation and exposure to chemicals
- 2012 - 2017 Role of non-homologous end joining in biological response under low dose-rate irradiation condition
- 2013 - 2015 Generation of ES cells to meseare DNA repair activity with reporter genes
- 2012 - 2015 Role of nucleolin in maintenance of genomic stability through chromatin remodeling
- 2011 - 2015 Roles of newly discovered NBS1 domains in ubiquitin signals and rejoining of double-strand breaks after irradiation
- 2009 - 2011 Role of nucleolus and related proteins for genomic stability
- 2005 - 2009 FUNCTIONAL ANALYSIS OF CANCER-SUSCEPTIBIE GENE, NBS1
- 2006 - 2007 ヒト放射線誘発がんの分子機構に関する研究
- 2006 - 2007 The role of BRCT domain in DNA damage response
- 2005 - 2005 長期的視点に立ったアジア地域の放射線科学研究基盤強化のための若手研究者の連携
- 2002 - 2005 Origin of radiation-induced genomic instability
- 2004 - 2004 放射線誘導DNA損傷応答の検知・認識機構の解析
- 2000 - 2004 Cancersusceptibility disease Nijmegen Breakage Syndrome and the function of underlying gene.
- 2000 - 2001 放射線照射による初期細胞応答反応におけるNBSI,ATMの相互作用の解析
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Papers (150):
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Takashi Oizumi, Tomoya Suzuki, Junya Kobayashi, Asako J Nakamura. Senescence-Associated Heterochromatin Foci Suppress γ-H2AX Focus Formation Induced by Radiation Exposure. International journal of molecular sciences. 2024. 25. 6
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Rikiya Imamura, Mizuki Saito, Mikio Shimada, Junya Kobayashi, Masamichi Ishiai, Yoshihisa Matsumoto. APTX acts in DNA double-strand break repair in a manner distinct from XRCC4. Journal of Radiation Research. 2023. 64. 3. 485-495
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Nobuhiro Morishima, Hiromitsu Ogata, Junji Magae, Yoshihiro Ito, Junya Kobayashi. Analysis method of cellular stress caused by intermediate dose-rate irradiation using a cell lysate array technique. Genes to Cells. 2023. 28. 288-306
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Mikio Shimada, Takumi Tokumiya, Tomoko Miyake, Kaima Tsukada, Norie Kanzaki, Hiromi Yanagihara, Junya Kobayashi, Yoshihisa Matsumoto. Implication of E3 ligase RAD18 in UV-induced mutagenesis in human induced pluripotent stem cells and neuronal progenitor cells. Journal of radiation research. 2023
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Hisayo Tsuchiya, Mikio Shimada, Kaima Tsukada, Qingmei Meng, Junya Kobayashi, Yoshihisa Matsumoto. THE ROLE OF DNA DOUBLE-STRAND BREAK REPAIR THROUGH NON-HOMOLOGOUS END JOINING IN THE DOSE-RATE EFFECT IN TERMS OF CLONOGENIC ABILITY. Radiation Protection Dosimetry. 2022. 198. 13-15. 990-997
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MISC (89):
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秋山(張)秋梅, 吉川幸宏, 趙Ting Yi, 山崎晃, 高雄雅, 小林純也, 冨田雅典, 鈴木雅雄. ヒトOGG1遺伝子高発現細胞の酸化ストレスに対する感受性と損傷の変化. 日本酸化ストレス学会学術集会プログラム・抄録集. 2018. 71st
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秋山 秋梅[張], 松井 亜子, 橋口 一成, 細木 彩夏, 小林 純也. 放射線発がんにおける酸化ストレス応答とミトコンドリアの相互作用 ヒトOXR1の放射線応答と細胞周期制御. 日本放射線影響学会大会講演要旨集. 2017. 60回. 91-91
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松井 亜子, 小林 純也, 橋口 一成, 安井 明, 秋山 秋梅[張]. Oxidation Resistance 1(OXR1)は放射線照射による細胞機構異常を防御している. 日本放射線影響学会大会講演要旨集. 2017. 60回. 117-117
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吉川幸宏, 山崎晃, 鈴木雅雄, 小林純也, 冨田雅典, 秋山(張)秋梅. 8-oxoG修復タンパクOGG1過剰発現の細胞影響. 日本放射線影響学会大会抄録(Web). 2017. 60th
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松井 亜子, 小林 純也, 橋口 一成, 鈴木 雅雄, 秋山 秋梅[張]. 放射線照射によるsuperoxideの蓄積が核ゲノム不安定性を促進する 細胞質におけるhOXR1による放射線防護機能. 日本放射線影響学会大会講演要旨集. 2016. 59回. 22-22
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Books (6):
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低線量リスクに関するコンセンサスと課題
放射線生物研究会(第55巻第2号:特別号) 2020
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DNA Repair Disorders
Springer 2019
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Radiation Medical Science
Iryokagakusya (Japan) 2016
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Etiology and Pathogenesis of Periodontal Disease
Springer (Berlin) 2010
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Genetic Variants in Periodontal Health and Disease
Springer (Berlin) 2009
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Lectures and oral presentations (26):
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市民公開講座「放射線とわたしたちの生活」
(2022年度国際医療福祉大学成田キャンパス公開講座 2022)
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低線量率放射線に対するヒト正常細胞の応答と酸化ストレス、ミトコンドリアとの関係
(第8回低線量放射線研究交流会 2022)
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低線量放射線影響研究と放射線生物学教育
(放射線生物学東京談話会(東京RBC) 2021)
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低線量放射線の生体影響の解明
(日本歯科放射線学会第1回秋季学術大会 2020)
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毛細血管拡張性運動失調症とATMキナーゼの役割
(第13回Quantum Medicine研究会 2020)
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Works (6):
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Analysis of biological effects under low dose rate of irradiation
2010 - 現在
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Role of nucleolar proteins in genome stability
2007 - 現在
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Analysis of AT-like disorders and the responsble genes
2006 - 現在
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Function of NBS1 and related genes in DNA damage and steress responses
1999 - 現在
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Fuction of WRN in DNA repair
2003 - 2010
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Education (3):
- 1991 - 1994 Hiroshima University Graduate School of Medicine
- 1989 - 1991 Kwansei Gakuin University Graduate School of Science
- 1985 - 1989 Kwansei Gakuin University School of Science
Professional career (2):
- PhD (Pharmaceutical Science) (Hiroshima University)
- MSc (Chemistry) (Kwansei Gakuin University)
Work history (7):
Committee career (5):
- 2020/06 - 現在 The Japanese Radiatin Researc Soociety vice chief director
- 2015/05 - 現在 Radiation Biology Reseach Communications Chief secretory
- 2005/04 - 現在 Journal of Radiation Research associate editor
- 2015/06 - 2020/06 The Japanese Radiatin Researc Soociety director
- 2001 - 2002 若手放射線生物学研究会 会長
Awards (2):
- 2003/10 - The Japan Radiation Research Society Young Award of The Japan Radiation Research Society
- 2002/09 - The Japan Radiation Research Society Annual meeting award of The Japan Radiation Research Society
Association Membership(s) (4):
The Japanese Biochemistry Society
, 日本癌学会
, The Molecular Biology Society of Japan
, The Japan Radation Research Society
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